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Chapter 5 - Hematolymphoid tumors

Published online by Cambridge University Press:  05 July 2016

Ophelia E. Dadzie
Affiliation:
Hillingdon Hospitals NHS Foundation Trust
Meera Mahalingam
Affiliation:
VA Consolidated Laboratories, New England
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Publisher: Cambridge University Press
Print publication year: 2000

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References

Primary Sources

Willemze, R, Jaffe, ES, Burg, G, et al. (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Swerdlow, SH, Campo, E, Harris, NL, et al. (2008). World Health Organization Classification of Tumors of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press.Google Scholar
Jaffe, ES (1999). Hematopathology: integration of morphologic features and biologic markers for diagnosis. Mod Pathol. Feb;12(2):109–15.Google Scholar
Wood, B (2006). 9-color and 10-color flow cytometry in the clinical laboratory. Arch Pathol Lab Med. May;130(5):680–90.CrossRefGoogle ScholarPubMed

Secondary Sources

Santucci, M, Biggeri, A, Feller, AC, Massi, D, Burg, G (2000). Efficacy of histologic criteria for diagnosing early mycosis fungoides: an EORTC cutaneous lymphoma study group investigation. European Organization for Research and Treatment of Cancer. Am J Surg Pathol. Jan;24(1):4050.Google Scholar
Diamandidou, E, Colome-Grimmer, M, Fayad, L, et al (1998). Transformation of mycosis fungoides/Sezary syndrome: clinical characteristics and prognosis. Blood. 92(4):1150–9.Google Scholar
Massone, C, Kodama, K, Kerl, H, Cerroni, L (2005). Histopathologic features of early (patch) lesions of mycosis fungoides: a morphologic study on 745 biopsy specimens from 427 patients. Am J Surg Pathol. Apr;29(4):550–60.CrossRefGoogle Scholar
Cerroni, L, Fink-Puches, R, El-Shabrawi-Caelen, L, et al (1999). Solitary skin lesions with histopathologic features of early mycosis fungoides. Am J Dermatopathol. Dec;21(6):518–24.Google Scholar
Toro, JR, Sander, CA, LeBoit, PE (1997). Persistent pigmented purpuric dermatitis and mycosis fungoides: simulant, precursor, or both? A study by light microscopy and molecular methods. Am J Dermatopathol. Apr;19(2):108–18.CrossRefGoogle ScholarPubMed
Hession, MT, Scheinman, PL (2010). Lymphomatoid allergic contact dermatitis mimicking cutaneous T cell lymphoma. Dermatitis. Jul-Aug;21(4):220.Google Scholar
Rodríguez Pinilla, SM, Roncador, G, Rodríguez-Peralto, JL, et al. (2009). Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma expresses follicular T-cell markers. Am J Surg Pathol. Jan;33(1):8190.CrossRefGoogle ScholarPubMed
Grogg, KL, Jung, S, Erickson, LA, McClure, RF, Dogan, A (2008). Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior. Mod Pathol. Jun;21(6):708–15.Google Scholar
Gerami, P, Rosen, S, Kuzel, T, Boone, SL, Guitart, J (2008). Folliculotropic mycosis fungoides: an aggressive variant of cutaneous T-cell lymphoma. Arch Dermatol. Jun;144(6):738–46.Google Scholar
Muniesa, C, Estrach, T, Pujol, RM, et al (2010). Folliculotropic mycosis fungoides: clinicopathologic features and outcome in a series of 20 cases. J Am Acad Dermatol. Mar;62(3):418–26.CrossRefGoogle Scholar
Mantaka, P, Helsing, P, Gjersvik, P, et al. (2013). Clinical and histopathologic features of folliculotropic mycosis fungoides: a Norwegian patient series. Acta Derm Venereol. May;93(3):325–9.CrossRefGoogle ScholarPubMed
Haghighi, B, Smoller, BR, LeBoit, PE, et al (2000). Pagetoid reticulosis (Woringer-Kolopp disease): an immunophenotypic, molecular, and clinicopathologic study. Mod Pathol. May;13(5):502–10.CrossRefGoogle ScholarPubMed
Cardoso, J, Duhra, P, Thway, Y, Calonje, E (2012). Lymphomatoid papulosis type D: a newly described variant easily confused with cutaneous aggressive CD8-positive cytotoxic T-cell lymphoma. Am J Dermatopathol. Oct;34(7):762–5.Google Scholar
Jacyk, WK, Grayson, W, Dinkel, JE, Requena, L (2007). Pagetoid reticulosis with CD30 positivity and cytotoxic/suppressor cells. J Cutan Pathol. Aug;34(8):644–7.CrossRefGoogle ScholarPubMed
Mourtzinos, N, Puri, PK, Wang, G, Liu, ML (2010). CD4/CD8 double negative pagetoid reticulosis: a case report and literature review. J Cutan Pathol. Apr;37(4):491–6.Google Scholar
DeGregorio, R, Fenske, NA, Glass, LF (1995). Granulomatous slack skin: a possible precursor of Hodgkin's disease. J Am Acad Dermatol. Dec;33(6):1044–7.CrossRefGoogle ScholarPubMed
Kempf, W, Ostheeren-Michaelis, S, Paulli, M, et al (2008). Cutaneous Lymphoma Histopathology Task Force Group of the European Organization for Research and Treatment of Cancer. Granulomatous mycosis fungoides and granulomatous slack skin: a multicenter study of the Cutaneous Lymphoma Histopathology Task Force Group of the European Organization For Research and Treatment of Cancer (EORTC). Arch Dermatol. Dec;144(12):1609–17.CrossRefGoogle ScholarPubMed
Ikonomou, IM, Aamot, HV, Heim, S, Fosså, A, Delabie, J (2007). Granulomatous slack skin with a translocation t(3;9)(q12;p24). Am J Surg Pathol. May;31(5):803–6.CrossRefGoogle Scholar
Olsen, E, Vonderheid, E, Pimpinelli, N, et al (2007); ISCL/EORTC. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood. Sep 15;110(6):1713–22.Google Scholar
Jawed, SI, Myskowski, PL, Horwitz, S, Moskowitz, A, Querfeld, C (2014). Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome): part I. Diagnosis: clinical and histopathologic features and new molecular and biologic markers. J Am Acad Dermatol. Feb;70(2):205.Google Scholar
Kelemen, K, White, CR, Gatter, K, Braziel, RM, Fan, G (2010). Immunophenotypic correlation between skin biopsy and peripheral blood findings in mycosis fungoides. Am J Clin Pathol, 134:739–48.CrossRefGoogle ScholarPubMed
Jones, D, Dang, NH, Duvic, M, Washington, LT, Huh, YO (2001). Absence of CD26 expression is a useful marker for diagnosis of T-cell lymphoma in peripheral blood. Am J Clin Pathol, 115:885–92.CrossRefGoogle ScholarPubMed
Diamandidou, E, Colome-Grimmer, M, Fayad, L, et al (1998). Transformation of mycosis fungoides/Sezary syndrome: clinical characteristics and prognosis. Blood. 92(4):1150–9.Google Scholar
Blayney, DW, Jaffe, ES, Fisher, RI, et al. (1983). The human T-cell leukemia/lymphoma virus, lymphoma, lytic bone lesions, and hypercalcemia. Ann Intern Med. Feb;98(2):144–51.Google Scholar
Yamaguchi, T, Ohshima, K, Karube, K, et al. (2005). Clinicopathologic features of cutaneous lesions of adult T-cell leukaemia/lymphoma. Br J Dermatol. Jan;152(1):7681.Google Scholar
Bittencourt, AL, Barbosa, HS, Vieira, MD, Farré, L (2009). Adult T-cell leukemia/lymphoma (ATL) presenting in the skin: clinical, histologic and immunohistochemical features of 52 cases. Acta Oncol. 48(4):598604.Google Scholar
Karube, K, Aoki, R, Sugita, Y, et al. (2008). The relationship of FOXP3 expression and clinicopathologic characteristics in adult T-cell leukemia/lymphoma. Mod Pathol. May;21(5):617–25.Google Scholar
Karube, K, Suzumiya, J, Okamoto, M, et al. (2007). Adult T-cell lymphoma/leukemia with angioimmunoblastic T-cell lymphomalike features: Report of 11 cases. Am J Surg Pathol. Feb;31(2):216–23.Google Scholar
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Diamandidou, E, Colome-Grimmer, M, Fayad, L, et al (1998). Transformation of mycosis fungoides/Sezary syndrome: clinical characteristics and prognosis. Blood. 92(4):1150–9.CrossRefGoogle ScholarPubMed
Bekkenk, MW, Geelen, FA, van Voorst Vader, PC, et al (2000). Primary and secondary cutaneous CD30(+) lymphoproliferative disorders: a report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment. Blood. Jun 15;95(12):3653–61.Google Scholar
Velusamy, T, Kiel, MJ, Sahasrabuddhe, AA, et al (2014). A novel recurrent NPM1-TYK2 gene fusion in cutaneous CD30-positive lymphoproliferative disorders. Blood. Dec 11;124(25):3768–71.Google ScholarPubMed
Querfeld, C, Khan, I, Mahon, B, et al (2010). Primary cutaneous and systemic anaplastic large cell lymphoma: clinicopathologic aspects and therapeutic options. Oncology (Williston Park). Jun;24(7):574–87.Google Scholar
Werner, B, Massone, C, Kerl, H, Cerroni, L (2008). Large CD30-positive cells in benign, atypical lymphoid infiltrates of the skin. J Cutan Pathol. Dec;35(12):1100–7.Google Scholar
Kempf, W (2006). CD30+ lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators. J Cutan Pathol. Feb;33 Suppl 1:5870.CrossRefGoogle ScholarPubMed
Sharma, V, Xu, G, Petronic-Rosic, V, Gerami, P (2007). Clinicopathologic challenge. Regional lymphomatoid papulosis, type A. Int J Dermatol. Sep;46(9):905–9.Google Scholar
Cardoso, J, Duhra, P, Thway, Y, Calonje, E (2012). Lymphomatoid papulosis type D: a newly described variant easily confused with cutaneous aggressive CD8-positive cytotoxic T-cell lymphoma. Am J Dermatopathol. Oct;34(7):762–5.CrossRefGoogle Scholar
Kempf, W, Kazakov, DV, Schärer, L, et al (2013). Angioinvasive lymphomatoid papulosis: a new variant simulating aggressive lymphomas. Am J Surg Pathol. Jan;37(1):113.CrossRefGoogle ScholarPubMed
Plaza, JA, Feldman, AL, Magro, C (2013). Cutaneous CD30-positive lymphoproliferative disorders with CD8 expression: a clinicopathologic study of 21 cases. J Cutan Pathol. Feb;40(2):236–47.CrossRefGoogle ScholarPubMed
Kumar, S, Krenacs, L, Medeiros, J, et al (1998). Subcutaneous panniculitic T-cell lymphoma is a tumor of cytotoxic T lymphocytes. Hum Pathol. Apr;29(4):397403.Google Scholar
Hoque, SR, Child, FJ, Whittaker, SJ, et al (2003). Subcutaneous panniculitis-like T-cell lymphoma: a clinicopathological, immunophenotypic and molecular analysis of six patients. Br J Dermatol. Mar;148(3):516–25.Google Scholar
Kong, YY, Dai, B, Kong, JC, et al. (2008). Subcutaneous panniculitis-like T-cell lymphoma: a clinicopathologic, immunophenotypic, and molecular study of 22 Asian cases according to WHO-EORTC classification. Am J Surg Pathol. Oct;32(10):1495–502.CrossRefGoogle ScholarPubMed
Willemze, R, Jansen, PM, Cerroni, L, et al (2008). EORTC Cutaneous Lymphoma Group. Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC Cutaneous Lymphoma Group Study of 83 cases. Blood. Jan 15;111(2):838–45Google Scholar
Jones, D, Vega, F, Sarris, AH, Medeiros, LJ (2002). CD4-CD8-”Double-negative” cutaneous T-cell lymphomas share common histologic features and an aggressive clinical course. Am J Surg Pathol. Feb;26(2):225–31.Google Scholar
Rodríguez-Pinilla, SM, Ortiz-Romero, PL, Monsalvez, V, et al (2013). TCR-γ expression in primary cutaneous T-cell lymphomas. Am J Surg Pathol. Mar;37(3):375–84.Google Scholar
Berti, E, Cerri, A, Cavicchini, S, et al. (1991). Primary cutaneous gamma/delta T-cell lymphoma presenting as disseminated pagetoid reticulosis. J Invest Dermatol. May;96(5):718–23.CrossRefGoogle ScholarPubMed
Toro, JR, Liewehr, DJ, Pabby, N, et al (2003). Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphoma. Blood. May 1;101(9):3407–12.CrossRefGoogle ScholarPubMed
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Berti, E, Tomasini, D, Vermeer, MH, et al (1999). Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas. A distinct clinicopathologic entity with an aggressive clinical behavior. Am J Pathol. Aug;155(2):483–92.Google Scholar
Robson, A, Assaf, C, Bagot, M, et al (2014). Aggressive Epidermotropic Cutaneous CD8+ Lymphoma: A cutaneous lymphoma with distinct clinical and pathologic features. Report of an EORTC Cutaneous Lymphoma Task Force Workshop. Histopathology. Jan 18. doi: 10.1111/his.12371. [Epub ahead of print].Google Scholar
Marzano, AV, Ghislanzoni, M, Gianelli, U, et al (2005). Fatal CD8+ epidermotropic cytotoxic primary cutaneous T-cell lymphoma with multiorgan involvement. Dermatology. 211(3):281–5.Google Scholar
Petrella, T, Maubec, E, Cornillet-Lefebvre, P, et al (2007). Indolent CD8-positive lymphoid proliferation of the ear: a distinct primary cutaneous T-cell lymphoma? Am J Surg Pathol. Dec;31(12):1887–92.Google Scholar
Beltraminelli, H, Müllegger, R, Cerroni, L (2010). Indolent CD8+ lymphoid proliferation of the ear: a phenotypic variant of the small-medium pleomorphic cutaneous T-cell lymphoma? J Cutan Pathol. Jan;37(1):81–4.Google Scholar
Beltraminelli, H, Leinweber, B, Kerl, H, Cerroni, L (2009). Primary cutaneous CD4+ small-/medium-sized pleomorphic T-cell lymphoma: a cutaneous nodular proliferation of pleomorphic T lymphocytes of undetermined significance? A study of 136 cases. Am J Dermatopathol. Jun;31(4):317–22.Google Scholar
Grogg, KL, Jung, S, Erickson, LA, McClure, RF, Dogan, A (2008). Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior. Mod Pathol. Jun;21(6):708–15.CrossRefGoogle ScholarPubMed
Cetinözman, F, Jansen, PM, Willemze, R (2012). Expression of programmed death-1 in primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma, cutaneous pseudo-T-cell lymphoma, and other types of cutaneous T-cell lymphoma. Am J Surg Pathol. Jan;36(1):109–16.Google Scholar
Rodríguez Pinilla, SM, Roncador, G, Rodríguez-Peralto, JL, et al (2009). Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma expresses follicular T-cell markers. Am J Surg Pathol. Jan;33(1):8190.Google Scholar
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.CrossRefGoogle ScholarPubMed
Swerdlow, SH, Campo, E, Harris, NL, et al (2008). World Health Organization Classification of Tumors of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press. pp. 285–8.Google Scholar
Takata, K, Hong, ME, Sitthinamsuwan, P, et al (2015). Primary cutaneous NK/T-cell lymphoma, nasal type and CD56-positive peripheral T-cell lymphoma: a cellular lineage and clinicopathologic study of 60 patients from Asia. Am J Surg Pathol. Jan;39(1):112.Google Scholar
Choi, YL, Park, JH, Namkung, JH, et al (2009). Extranodal NK/T-cell lymphoma with cutaneous involvement: ‘nasal’ vs. ‘nasal-type’ subgroups: a retrospective study of 18 patients. Br J Dermatol. Feb;160(2):333–7.Google Scholar
Liao, JB, Chuang, SS, Chen, HC, et al (2010). Clinicopathologic analysis of cutaneous lymphoma in Taiwan: a high frequency of extranodal natural killer/T-cell lymphoma, nasal type, with an extremely poor prognosis. Arch Pathol Lab Med. Jul;134(7):9961002.Google Scholar
Sitthinamsuwan, P, Pongpruttipan, T, Chularojmontri, L,et al. (2010). Extranodal NK/T cell lymphoma, nasal type, presenting with primary cutaneous lesion mimicking granulomatous panniculitis: a case report and review of literature. J Med Assoc Thai. Aug;93(8):1001–7.Google Scholar
Willemze, R, Jaffe, ES, Burg, G, et al. (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Kreisel, F (2011). Case Study Interpretation–Houston: Case 1. Phenytoin-induced ‘‘pseudolymphoma.’Cytometry B Clin Cytom. Jul-Aug;80(4):255–7.Google Scholar
Choi, TS, Doh, KS, Kim, SH, et al. (2003). Clinicopathologic and genotypic aspects of anticonvulsant-induced pseudolymphoma syndrome. Br J Dermatol. Apr;148(4):730–6.Google Scholar
Harris, DW, Ostlere, L, Buckley, C, et al (1992). Phenytoin-induced pseudolymphoma. A report of a case and review of the literature. Br J Dermatol. Oct;127(4):403–6.Google Scholar
Ramsay, B, Dahl, MC, Malcolm, AJ, Wilson-Jones, E (1990). Acral pseudolymphomatous angiokeratoma of children. Arch Dermatol. Nov;126(11):1524–5.CrossRefGoogle ScholarPubMed
Dayrit, JF, Wang, WL, Goh, SG, Ramdial, PK, Lazar, AJ, Calonje, E (2011). T-cell-rich angiomatoid polypoid pseudolymphoma of the skin: a clinicopathologic study of 17 cases and a proposed nomenclature. J Cutan Pathol. Jun;38(6):475–82.Google Scholar
Kaddu, S, Cerroni, L, Pilatti, A, Soyer, HP, Kerl, H (1994). Acral pseudolymphomatous angiokeratoma. A variant of the cutaneous pseudolymphomas. Am J Dermatopathol. Apr;16(2):130–3.CrossRefGoogle ScholarPubMed
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Morales, AV, Arber, DA, Seo, K, et al (2008). Evaluation of B-cell clonality using the BIOMED-2 PCR method effectively distinguishes cutaneous B-cell lymphoma from benign lymphoid infiltrates. Am J Dermatopathol. Oct;30(5):425–30.Google Scholar
Geyer, JT, Ferry, JA, Longtine, JA, et al (2010). Characteristics of cutaneous marginal zone lymphomas with marked plasmacytic differentiation and a T cell-rich background. Am J Clin Pathol. Jan;133(1):5969.Google Scholar
Ritter, JH, Wick, MR, Adesokan, PN, et al (1997). Assessment of clonality in cutaneous lymphoid infiltrates by polymerase chain reaction analysis of immunoglobulin heavy chain gene rearrangement. Am J Clin Pathol. Jul;108(1):60–8.Google Scholar
de Leval, L, Harris, NL, Longtine, J, Ferry, JA, Duncan, LM (2001). Cutaneous B-cell lymphomas of follicular and marginal zone types: use of Bcl-6, CD10, Bcl-2, and CD21 in differential diagnosis and classification. Am J Surg Pathol. Jun;25(6):732–41.Google Scholar
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Santucci, M, Pimpinelli, N, Arganini, L (1991). Primary cutaneous B-cell lymphoma: a unique type of low-grade lymphoma. Clinicopathologic and immunologic study of 83 cases. Cancer. May 1;67(9):2311–26.Google Scholar
Morales, AV, Arber, DA, Seo, K, et al (2008). Evaluation of B-cell clonality using the BIOMED-2 PCR method effectively distinguishes cutaneous B-cell lymphoma from benign lymphoid infiltrates. Am J Dermatopathol. Oct;30(5):425–30.CrossRefGoogle ScholarPubMed
Kempf, W, Kazakov, DV, Rütten, A, et al (2014). Primary cutaneous follicle center lymphoma with diffuse CD30 expression: a report of 4 cases of a rare variant. J Am Acad Dermatol. Sep;71(3):548–54.Google Scholar
Ritter, JH, Wick, MR, Adesokan, PN, et al. (1997). Assessment of clonality in cutaneous lymphoid infiltrates by polymerase chain reaction analysis of immunoglobulin heavy chain gene rearrangement. Am J Clin Pathol. Jul;108(1):60–8.Google Scholar
de Leval, L, Harris, NL, Longtine, J, Ferry, JA, Duncan, LM (2001). Cutaneous B-cell lymphomas of follicular and marginal zone types: use of Bcl-6, CD10, Bcl-2, and CD21 in differential diagnosis and classification. Am J Surg Pathol. Jun;25(6):732–41.CrossRefGoogle ScholarPubMed
Abdul-Wahab, A, Tang, SY, Robson, A, et al (2014). Chromosomal anomalies in primary cutaneous follicle center cell lymphoma do not portend a poor prognosis. J Am Acad Dermatol. Jun;70(6):1010–20.Google Scholar
Demirkesen, C, Tüzüner, N, Esen, T, Lebe, B, Ozkal, S (2011). The expression of IgM is helpful in the differentiation of primary cutaneous diffuse large B cell lymphoma and follicle center lymphoma. Leuk Res. Sep;35(9):1269–72.Google Scholar
Clarke, LE, Bayerl, MG, Ehmann, WC, Helm, KF (2003). Cutaneous B-cell lymphoma with loss of CD20 immunoreactivity after rituximab therapy. J Cutan Pathol. Aug;30(7):459–62.Google Scholar
Willemze, R, Meijer, CJ, Sentis, HJ, et al (1987). Primary cutaneous large cell lymphomas of follicular center cell origin. A clinical follow-up study of nineteen patients. J Am Acad Dermatol. Mar;16(3 Pt 1):518–26.Google Scholar
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.Google Scholar
Vermeer, MH, Geelen, FA, van Haselen, CW, et al (1996). Primary cutaneous large B-cell lymphomas of the legs. A distinct type of cutaneous B-cell lymphoma with an intermediate prognosis. Dutch Cutaneous Lymphoma Working Group. Arch Dermatol. Nov;132(11):1304–8.CrossRefGoogle ScholarPubMed
Plaza, JA, Kacerovska, D, Sangueza, M, et al (2014). Can cutaneous low-grade B-cell lymphoma transform into primary cutaneous diffuse large B-cell lymphoma? An immunohistochemical study of 82 cases. Am J Dermatopathol. Jun;36(6):478–82.CrossRefGoogle ScholarPubMed
Wiesner, T, Streubel, B, Huber, D, et al (2005). Genetic aberrations in primary cutaneous large B-cell lymphoma: a fluorescence in situ hybridization study of 25 cases. Am J Surg Pathol. May;29(5):666–73.Google Scholar
Hallermann, C, Kaune, KM, Gesk, S, et al (2004). Molecular cytogenetic analysis of chromosomal breakpoints in the IGH, MYC, BCL6, and MALT1 gene loci in primary cutaneous B-cell lymphomas. J Invest Dermatol. Jul;123(1):213–19.Google Scholar
Pham-Ledard, A, Prochazkova-Carlotti, M, Andrique, L, et al (2014). Multiple genetic alterations in primary cutaneous large B-cell lymphoma, leg type support a common lymphomagenesis with activated B-cell-like diffuse large B-cell lymphoma. Mod Pathol. Mar;27(3):402–11.Google Scholar
Hristov, AC (2012). Primary cutaneous diffuse large B-cell lymphoma, leg type: diagnostic considerations. Arch Pathol Lab Med. Aug;136(8):876–81.Google Scholar
Clarke, LE, Bayerl, MG, Ehmann, WC, Helm, KF (2003). Cutaneous B-cell lymphoma with loss of CD20 immunoreactivity after rituximab therapy. J Cutan Pathol. Aug;30(7):459–62.Google Scholar
Harris, NL, Jaffe, ES, Stein, H, et al (1994). A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood. Sep 1;84(5):1361–92.Google Scholar
Stein, H, Warnke, RA, Chan, WC, et al (2008). Diffuse large B-cell lymphoma, not otherwise specified. Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, pp. 233–7.Google Scholar
Lu, CS, Chen, JH, Huang, TC, et al (2015). Diffuse large B-cell lymphoma: sites of extranodal involvement are a stronger prognostic indicator than number of extranodal sites in the rituximab era. Leuk Lymphoma. Jan 14:19.Google Scholar
Ferreri, AJ, Campo, E, Seymour, JF, et al (2004). International Extranodal Lymphoma Study Group (IELSG). Intravascular lymphoma: clinical presentation, natural history, management and prognostic factors in a series of 38 cases, with special emphasis on the ‘cutaneous variant’. Br J Haematol. Oct;127(2):173–83.Google Scholar
Oyama, T, Yamamoto, K, Asano, N, et al (2007). Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients. Clin Cancer Res. Sep 1;13(17):5124–32.Google Scholar
Nakamura, S, Jaffe, E, Swerdlow, SH (2008). EBV positive diffuse large B-cell lymphoma of the elderly. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, pp. 233–7.Google Scholar
Willemze, R, Jaffe, ES, Burg, G, et al (2005). WHO-EORTC classification for cutaneous lymphomas. Blood. May 15;105(10):3768–85.CrossRefGoogle ScholarPubMed
Santucci, M, Pimpinelli, N, Arganini, L (1991). Primary cutaneous B-cell lymphoma: a unique type of low-grade lymphoma. Clinicopathologic and immunologic study of 83 cases. Cancer. May 1;67(9):2311–26.Google Scholar
Robak, E, Robak, T (2007). Skin lesions in chronic lymphocytic leukemia. Leuk Lymphoma. May;48(5):855–65.Google Scholar
Cerroni, L, Zenahlik, P, Höfler, G (1996). Specific cutaneous infiltrates of B-cell chronic lymphocytic leukemia: a clinicopathologic and prognostic study of 42 patients. Am J Surg Pathol. Aug;20(8):1000–10.Google Scholar
Duong, T, Grange, F, Auffret, N, et al. (2010). Cutaneous Richter's syndrome, prognosis, and clinical, histologic and immunohistologic patterns: report of four cases and review of the literature. Dermatology. 220(3):226–33CrossRefGoogle ScholarPubMed
Borowitz, MJ, Chan, JKC (2008). B lymphoblastic leukaemia/lymphoma, not otherwise specified. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, pp. 168–70.Google Scholar
Sander, CA, Jaffe, ES, Gebhardt, FC, Yano, T, Medeiros, LJ (1992). Mediastinal lymphoblastic lymphoma with an immature B-cell immunophenotype. Am J Surg Pathol. Mar;16(3):300–5.CrossRefGoogle ScholarPubMed
Lin, P, Jones, D, Dorfman, DM, Medeiros, LJ (2000). Precursor B-cell lymphoblastic lymphoma: a predominantly extranodal tumor with low propensity for leukemic involvement. Am J Surg Pathol. Nov;24(11):1480–90.Google Scholar
Vezzoli, P, Novara, F, Fanoni, D, et al (2012). Three cases of primary cutaneous lymphoblastic lymphoma: microarray-based comparative genomic hybridization and gene expression profiling studies with review of literature. Leuk Lymphoma. Oct;53(10):1978–87.Google Scholar
Maitra, A, McKenna, RW, Weinberg, AG, Schneider, NR, Kroft, SH (2001). Precursor B-cell lymphoblastic lymphoma. A study of nine cases lacking blood and bone marrow involvement and review of the literature. Am J Clin Pathol. Jun;115(6):868–75.Google Scholar
Pileri, SA, Orazi, A, Falini, B (2008). Myeloid sarcoma. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, pp. 140141.Google Scholar
Pileri, SA, Ascani, S, Cox, MC, et al (2007). Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia. Feb;21(2):340–50.Google Scholar
Alexiev, BA, Wang, W, Ning, Y, et al (2007). Myeloid sarcomas: a histologic, immunohistochemical, and cytogenetic study. Diagn Pathol. Oct 31;2:42.Google Scholar
Raphael, J, Valent, A, Hanna, C, et al (2014). Myeloid sarcoma of the nasopharynx mimicking an aggressive lymphoma. Head Neck Pathol. Jun;8(2):234–8.Google Scholar
Ojha, SS, Kothari, KS, Naik, LP, Fernandes, GC, Rangwala, S, Agnihotri, MA (2012). Dysplastic megakaryocytes and eosinophilic precursors in the diagnosis of myeloid sarcoma on lymph node fine-needle aspiration cytology: a case series. Acta Cytol. 56(3):325–9.Google Scholar
Sano, F, Tasaka, T, Nishimura, H, et al (2008). A peculiar case of acute myeloid leukemia mimicking plasmacytoid dendritic precursor cell leukemia. J Clin Exp Hematop. Nov;48(2):65–9.Google Scholar
Facchetti, F, Jones, DM, Petrella, T (2008). Blastic plasmacytoid dendritic cell neoplasm. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, pp. 145–7.Google Scholar
Paluri, R, Nabell, L, Borak, S, Peker, D (2014). Unique presentation of blastic plasmacytoid dendritic cell neoplasm: a single-center experience and literature review. Hematol Oncol. May 21, doi: 10.1002/hon.2147. [Epub ahead of print].CrossRefGoogle Scholar
Petrella, T, Bagot, M, Willemze, R, et al (2005). Blastic NK-cell lymphomas (agranular CD4+CD56+ hematodermic neoplasms): a review. Am J Clin Pathol. May;123(5):662–75.Google Scholar
Jacob, MC, Chaperot, L, Mossuz, P, et al (2003). CD4+ CD56+ lineage negative malignancies: a new entity developed from malignant early plasmacytoid dendritic cells. Haematologica. Aug;88(8):941–55.Google Scholar
Jegalian, AG, Facchetti, F, Jaffe, ES (2009). Plasmacytoid dendritic cells: physiologic roles and pathologic states. Adv Anat Pathol. Nov;16(6):392404.Google Scholar
Herling, M, Jones, D (2007). CD4+/CD56+ hematodermic tumor: the features of an evolving entity and its relationship to dendritic cells. Am J Clin Pathol. May;127(5):687700.Google Scholar
Jardin, F, Ruminy, P, Parmentier, F, et al (2011). TET2 and TP53 mutations are frequently observed in blastic plasmacytoid dendritic cell neoplasm. Br J Haematol. May;153(3):413–16.Google Scholar
Horny, H, Metcalfe, DD, Bennett, JM, et al (2008). Mastocytosis. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, pp. 5463.Google Scholar
Valent, P, Akin, C, Escribano, L et al (2007). Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria. Eur J Clin Invest. Jun;37(6):435–53.Google Scholar
Kiszewski, AE, Alvarez-Mendoza, A, Ríos-Barrera, VA, Hernández-Pando, R, Ruiz-Maldonado, R (2007). Mastocytosis in children: clinicopathologic study based on 35 cases. Histol Histopathol. May;22(5):535–9.Google Scholar
Wolff, K, Komar, M, Petzelbauer, P (2001). Clinical and histopathologic aspects of cutaneous mastocytosis. Leuk Res. Jul;25(7):519–28.CrossRefGoogle ScholarPubMed
Lanternier, F, Cohen-Akenine, A, Palmerini, F, et al (2008). AFIRMM network. Phenotypic and genotypic characteristics of mastocytosis according to the age of onset. PLoS One. Apr 9;3(4):e1906.Google Scholar
Berezowska, S, Flaig, MJ, Ruëff, F, et al (2014). Adult-onset mastocytosis in the skin is highly suggestive of systemic mastocytosis. Mod Pathol. Jan;27(1):1929.CrossRefGoogle ScholarPubMed
Jaffe, R, Weiss, LM, Facchetti, F (2008). Tumors derived from Langerhans cells. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, 358–60.Google Scholar
Favara, BE, Feller, AC, Pauli, M, et al (1997). Contemporary classification of histiocytic disorders. The WHO Committee on Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol. Sep;29(3):157–66.Google Scholar
Querings, K, Starz, H, Balda, BR (2006). Clinical spectrum of cutaneous Langerhans’ cell histiocytosis mimicking various diseases. Acta Derm Venereol. 86(1):3943.CrossRefGoogle ScholarPubMed
Sholl, LM, Hornick, JL, Pinkus, JL, Pinkus, GS, Padera, RF (2007). Immunohistochemical analysis of langerin in langerhans cell histiocytosis and pulmonary inflammatory and infectious diseases. Am J Surg Pathol. Jun;31(6):947–52.CrossRefGoogle ScholarPubMed
Badalian-Very, G, Vergilio, JA, Degar, BA, et al (2010). Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. Sep 16;116(11):1919–23.Google Scholar
Lau, SK, Chu, PG, Weiss, LM (2008). Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders. Am J Surg Pathol. Apr;32(4):615–19.CrossRefGoogle ScholarPubMed
Freyer, DR, Kennedy, R, Bostrom, BC, Kohut, G, Dehner, LP (1996). Juvenile xanthogranuloma: forms of systemic disease and their clinical implications. J Pediatr. Aug;129(2):227–37.Google Scholar
Dehner, LP (2003). Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations. Am J Surg Pathol. May;27(5):579–93.Google Scholar
Fenot, M, Stalder, JF, Barbarot, S (2014). Juvenile xanthogranulomas are highly prevalent but transient in young children with neurofibromatosis type 1. J Am Acad Dermatol. Aug;71(2):389–90.Google Scholar
Price, HN, Zaenglein, AL (2007). Diagnosis and management of benign lumps and bumps in childhood. Curr Opin Pediatr. Aug;19(4):420–4.Google Scholar
Cham, E, Siegel, D, Ruben, BS (2010). Cutaneous xanthogranulomas, hepatosplenomegaly, anemia, and thrombocytopenia as presenting signs of juvenile myelomonocytic leukemia. Am J Clin Dermatol. 11(1):6771.Google Scholar
Barrow, MV, Holubar, K (1969). Multicentric reticulohistiocytosis: a review of 33 patients. Medicine 48(4): 287305.Google Scholar
Tajirian, AL, Malik, MK, Robinson-Bostom, L, Lally, EV (2006). Multicentric reticulohistiocytosis. Clin Dermatol. Nov–Dec;24(6):486–92.Google Scholar
Mun, JH, Ko, HC, Kim, MB (2012). Multicentric reticulohistiocytosis masquerading as dermatomyositis: similar and different features. J Dermatol. Jan;39(1):104–7.CrossRefGoogle ScholarPubMed
Munoz-Santos, C, Sàbat, M, Sáez, A, Gratacós, J, Luelmo, J. (2007). Multicentric reticulohistiocytosis-mimicking dermatomyositis. Dermatology 214(3):268–71.CrossRefGoogle ScholarPubMed
Ortiz-Hidalgo, C, Cuesta-Mejías, TC, Ochoa-Ochoa, C, Valenzuela-Espinosa, A, Toussaint-Caire, S (2003). [Rosai-Dorfman disease limited to the skin. Four case reports]. Gac Med Mex. Jan–Feb;139(1):16.Google Scholar
Eisen, RN, Buckley, PJ, Rosai, J (1990). Immunophenotypic characterization of sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease). Semin Diagn Pathol. Feb;7(1):7482.Google Scholar
Foucar, E, Rosai, J, Dorfman, RF (1984). Sinus histiocytosis with massive lymphadenopathy. An analysis of 14 deaths occurring in a patient registry. Cancer. Nov 1;54(9):1834–40.Google Scholar
O'Malley, DP, Duong, A, Barry, TS, et al (2010). Co-occurrence of Langerhans cell histiocytosis and Rosai–Dorfman disease: possible relationship of two histiocytic disorders in rare cases. Mod Pathol. Dec;23(12):1616–23.Google Scholar
Wang, RF, Han, W, Qi, L, Shan, LH, Wang, ZC, Wang, LF (2015). Extranodal follicular dendritic cell sarcoma: A clinicopathologic report of four cases and a literature review. Oncol Lett. Jan;9(1):391–8.Google Scholar
Kazakov, DV, Morrisson, C, Plaza, JA, Michal, M, Suster, S (2005). Sarcoma arising in hyaline-vascular castleman disease of skin and subcutis. Am J Dermatopathol. Aug;27(4):327–32.Google Scholar
Orii, T, Takeda, H, Kawata, S, Maeda, K, Yamakawa, M (2010) Differential immunophenotypic analysis of dendritic cell tumors. J Clin Pathol. Jun;63(6):497503Google Scholar
Pillay, K, Solomon, R, Daubenton, JD, Sinclair-Smith, CC (2004). Interdigitating dendritic cell sarcoma: a report of four paediatric cases and review of the literature. Histopathology. Mar;44(3):283–91.Google Scholar
Vasef, MA, Zaatari, GS, Chan, WC, Sun, NC, Weiss, LM, Brynes, RK (1995). Dendritic cell tumors associated with low-grade B-cell malignancies. Report of three cases. Am J Clin Pathol. Dec;104(6):696701.Google Scholar
Pileri, SA, Grogan, TM, Harris, NL, et al (2002). Tumors of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology. Jul;41(1):129.Google Scholar
Nakamura, S, Hara, K, Suchi, T, et al (1988). Interdigitating cell sarcoma. A morphologic, immunohistologic, and enzyme-histochemical study. Cancer. Feb 1;61(3):562–8.Google Scholar
Weiss, LM, Chan, JKC, Fletcher, CDM (2008). Other rare dendritic cell tumors. In Swerdlow, SH, Campo, E, Harris, NL et al. WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. 4th Edn. France: IARC Lyon, 365.Google Scholar
Rezk, SA, Spagnolo, DV, Brynes, RK, Weiss, LM (2008). Indeterminate cell tumor: a rare dendritic neoplasm. Am J Surg Pathol. Dec;32(12):1868–76.Google Scholar

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