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Chapter 8 - Primary Amenorrhoea and Delayed Puberty

Published online by Cambridge University Press:  28 January 2023

By
Elizabeth Burt  and
Ephia Yasmin
Edited by
Naomi S. Crouch  and
Cara E. Williams
Naomi S. Crouch
Affiliation:
St Michael's Hospital, Bristol
Cara E. Williams
Affiliation:
Liverpool Women's Hospital
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Summary

Female puberty, driven by the hypothalamic–pituitary–ovarian axis (HPO), sees numerous alterations in the body secondary to the rise in oestradiol concentration. Whilst the onset, tempo and sequence will vary between individuals, delay in initiation of events or arrest during the process warrants medical attention. Pubertal transition requires not only an intact HPO axis but also functional reproductive organs.

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Chapter
Information
Paediatric and Adolescent Gynaecology for the MRCOG , pp. 57 - 66
Publisher: Cambridge University Press
Print publication year: 2023

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