Skip to main content Accessibility help
×
Hostname: page-component-848d4c4894-8bljj Total loading time: 0 Render date: 2024-06-23T08:43:59.372Z Has data issue: false hasContentIssue false

Chapter 11 - Preoperative and postoperative hypertension

from Section 3 - Hypertension

Published online by Cambridge University Press:  05 September 2013

Michael F. Lubin
Affiliation:
Emory University, Atlanta
Thomas F. Dodson
Affiliation:
Emory University, Atlanta
Neil H. Winawer
Affiliation:
Emory University, Atlanta
Get access

Summary

Introduction

Hypertension affects an estimated 76 million persons in the USA, including one in three adults and more than 65% of individuals over age 65 years [1]. Thus, it is a very common disorder affecting many surgical patients. Hypertension often causes end-organ damage of the brain, heart, and kidneys, with important implications for surgical risk and perioperative management. Patients with chronic hypertension will often have perioperative episodes of hypertension that will require intervention. In addition, postoperative hypertension is common even without preexisting hypertension, especially in patients undergoing cardiac or carotid surgery. This chapter concentrates on the preoperative risk assessment and management of hypertensive patients and on the perioperative management of hypertension.

Hemodynamic response to anesthesia

A discussion of perioperative hypertension requires a basic understanding of the physiologic responses to anesthesia in normotensive and hypertensive patients. There are four main periods during anesthesia: induction, intubation, maintenance, and recovery periods. During induction, most patients' blood pressure falls. During laryngoscopy and intubation, the sympathetic nervous system is activated and blood pressure and heart rate rise. With deepening anesthesia, a decline in mean arterial pressure and heart rate occur due to the effects of pharmacologic agents, a decrease in sympathetic nervous system activity, and loss of the baroreceptor reflex. During recovery from anesthesia around the time of extubation, blood pressure and heart rate slowly increase in the first 15 minutes, and are accompanied by general arousal.

Type
Chapter
Information
Medical Management of the Surgical Patient
A Textbook of Perioperative Medicine
, pp. 119 - 132
Publisher: Cambridge University Press
Print publication year: 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Roger, VL, Go, AS, Lloyd-Jose, DM et al. Heart disease and stroke statistics – 2011 update: a report from the American Heart Association. Circulation 2011; 123: e18–209.CrossRefGoogle ScholarPubMed
Wolfsthal, SD.Is blood pressure control necessary before surgery?Med Clin North Am 1993; 77: 349–63.CrossRefGoogle ScholarPubMed
Prys-Roberts, C, Greene, LT, Meloche, R et al. Studies of anaesthesia in relation to hypertension. II. Haemodynamic consequences of induction and endotracheal intubation. Br J Anaesth 1971; 43: 531–47.CrossRefGoogle ScholarPubMed
Prys-Roberts, C, Meloche, R, Foex, P.Studies of anaesthesia in relation to hypertension. I. Cardiovascular responses of treated and untreated patients. Br J Anaesth 1971; 43: 122–37.CrossRefGoogle ScholarPubMed
Charlson, ME, MacKenzie, CR, Gold, JP et al. The preoperative and intraoperative hemodynamic predictors of postoperative myocardial infarction or ischemia in patients undergoing noncardiac surgery. Ann Surg 1989; 210: 637–48.CrossRefGoogle ScholarPubMed
Slogoff, S, Keats, AS.Does perioperative myocardial ischemia lead to postoperative myocardial infarction?Anesthesiology 1985; 62: 107–14.CrossRefGoogle ScholarPubMed
Raby, KE, Barry, J, Creager, MA et al. Detection and significance of intraoperative and postoperative myocardial ischemia in peripheral vascular surgery. J Am Med Assoc 1992; 268: 222–7.CrossRefGoogle ScholarPubMed
Hollenberg, M, Mangano, DT, Browner, WS et al. Predictors of postoperative myocardial ischemia in patients undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. J Am Med Assoc 1992; 268: 205–9.CrossRefGoogle Scholar
Mangano, DT, Browner, WS, Hollenberg, M et al. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. N Engl J Med 1990; 323: 1781–8.CrossRefGoogle Scholar
Goldman, L, Caldera, DL.Risks of general anesthesia and elective operation in the hypertensive patient. Anesthesiology 1979; 50: 285–92.CrossRefGoogle ScholarPubMed
Goldman, L, Caldera, DL, Nussbaum, SR et al. Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med 1977; 297: 845–50.CrossRefGoogle ScholarPubMed
Detsky, AS, Abrams, HB, McLaughlin, JR et al. Predicting cardiac complications in patients undergoing non-cardiac surgery. J Gen Intern Med 1986; 1: 211–19.CrossRefGoogle ScholarPubMed
Lee, TH, Marcantonio, ER, Mangione, CM et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation 1999; 100: 1043–9.CrossRefGoogle ScholarPubMed
Browner, WS, Li, J, Mangano, DT.In-hospital and long-term mortality in male veterans following noncardiac surgery. The Study of Perioperative Ischemia Research Group. J Am Med Assoc 1992; 268: 228–32.CrossRefGoogle Scholar
Goldman, L, Caldera, DL, Southwick, FS et al. Cardiac risk factors and complications in non-cardiac surgery. Medicine (Baltimore) 1978; 57: 357–70.CrossRefGoogle ScholarPubMed
Charlson, ME, MacKenzie, CR, Gold, JP et al. Risk for postoperative congestive heart failure. Surg Gynecol Obstet 1991; 172: 95–104.Google ScholarPubMed
Landesberg, G, Einav, S, Christopherson, R et al. Perioperative ischemia and cardiac complications in major vascular surgery: importance of the preoperative twelve-lead electrocardiogram. J Vasc Surg 1997; 26: 570–8.CrossRefGoogle ScholarPubMed
Porhomayon, J, El-Solh, A, Chhangani, S et al. The management of surgical patients with obstructive sleep apnea. Lung 2011; 189(5): 359–67.CrossRefGoogle ScholarPubMed
Edwards, R.Thyroid and parathyroid disease. Int Anesth Clin 1997; 35: 62.CrossRefGoogle ScholarPubMed
Sellevold, OF, Raeder, J, Stenseth, R.Undiagnosed phaeochromocytoma in the perioperative period. Case reports. Acta Anaesthesiol Scand 1985; 29: 474–9.CrossRefGoogle ScholarPubMed
Chen, H, Sippel, RS, O'Dorisio, et al. The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors. Pancreas 2010; 39: 775–83.CrossRefGoogle ScholarPubMed
The Seventh Report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. J Am Med Assoc 2003; 289: 2560–72.
Casadei, B, Abuzeid, H.Is there a strong rationale for deferring elective surgery in patients with poorly controlled hypertension. J Hypertens 2005; 23: 19–22.CrossRefGoogle Scholar
Weksler, N, Klein, M, Szendro, G et al. The dilemma of immediate preoperative hypertension: to treat and operate, or to postpone surgery?J Clinc Anesth 2003; 15: 179–83.CrossRefGoogle ScholarPubMed
Psaty, BM, Smith, NL, Siscovick, DS et al. Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis. J Am Med Assoc 1997; 277: 739–45.CrossRefGoogle ScholarPubMed
Yusuf, S, Sleight, P, Pogue, J et al. Effects of an angiotensin-converting enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 2000; 342: 145–53.Google ScholarPubMed
Houston, MC.Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome. Am Heart J 1981; 102: 415–30.CrossRefGoogle ScholarPubMed
Hart, GR, Anderson, RJ.Withdrawal syndromes and the cessation of antihypertensive therapy. Arch Intern Med 1981; 141: 1125–7.CrossRefGoogle ScholarPubMed
Shammash, JB, Trost, JC, Gold, JM et al. Perioperative beta-blocker withdrawal and mortality in vascular surgical patients. Am Heart J 2001; 141: 148–53.CrossRefGoogle ScholarPubMed
Prys-Roberts, C.Interactions of anaesthesia and high preoperative doses of beta-receptor antagonists. Acta Anaesthesiol Scand Suppl 1982; 76: 47–53.CrossRefGoogle Scholar
Prys-Roberts, C, Foex, P, Biro, GP et al. Studies of anaesthesia in relation to hypertension. V. Adrenergic beta-receptor blockade. Br J Anaesth 1973; 45: 671–81.CrossRefGoogle ScholarPubMed
Pasternack, PF, Grossi, EA, Baumann, FG et al. Beta blockade to decrease silent myocardial ischemia during peripheral vascular surgery. Am J Surg 1989; 158: 113–16.CrossRefGoogle ScholarPubMed
Wallace, AW.Clonidine and modification of perioperative outcome. Curr Opin Anaesthesiol 2006; 19: 411–17.CrossRefGoogle ScholarPubMed
Wallace, AW, Galindez, D, Salahieh, A et al. Effect of clonidine on cardiovascular morbidity and mortality after noncardiac surgery. Anesthesiology 2004; 101: 284–93.CrossRefGoogle ScholarPubMed
Bernstein, JS.Transdermal clonidine therapy for the perioperative period. Anesthesiology 1986; 65: 451.CrossRefGoogle ScholarPubMed
Johnston, RV, Nicholas, DA, Lawson, NW et al. The use of rectal clonidine in the perioperative period. Anesthesiology 1986; 64: 288–90.CrossRefGoogle ScholarPubMed
Coriat, P, Richer, C, Douraki, T et al. Influence of chronic angiotensin-converting enzyme inhibition on anesthetic induction. Anesthesiology 1994; 81: 299–307.CrossRefGoogle ScholarPubMed
Comfere, T, Sprung, J, Kumar, MM et al. Angiotensin system inhibitors in a general surgical population. Anesth Analg 2005; 100: 636–44.CrossRefGoogle Scholar
Bertrand, M, Godet, G, Meersschaert, K et al. Should the angiotensin II antagonists be discontinued before surgery?Anesth Analg 2001; 92: 26–30.CrossRefGoogle ScholarPubMed
Kehterpal, S, Khodaparast, O, Shanks, A et al. Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery. J Cardiothorac Vasc Anesth 2008; 22: 180–6.CrossRefGoogle Scholar
Pigott, DW, Nagle, C, Allman, K et al. Effect of omitting regular ACE inhibitor medication before cardiac surgery on haemodynamic variables and vasoactive drug requirements. Br J Anaesth 1999; 83: 715–20.CrossRefGoogle ScholarPubMed
Chauvin, M, Deriaz, H, Viars, P.Continuous i.v. infusion of labetalol for postoperative hypertension. Haemodynamic effects and plasma kinetics. Br J Anaesth 1987; 59: 1250–6.CrossRefGoogle ScholarPubMed
Cosentino, F, Vidt, DG, Orlowski, JP et al. The safety of cumulative doses of labetalol in perioperative hypertension. Cleve Clin J Med 1989; 56: 371–6.CrossRefGoogle ScholarPubMed
Cruise, CJ, Skrobik, Y, Webster, RE et al. Intravenous labetalol versus sodium nitroprusside for treatment of hypertension postcoronary bypass surgery. Anesthesiology 1989; 71: 835–9.CrossRefGoogle ScholarPubMed
Dimich, I, Lingham, R, Gabrielson, G et al. Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. J Clin Anesth 1989; 1: 201–6.CrossRefGoogle ScholarPubMed
Geniton, DJ.A comparison of the hemodynamic effects of labetalol and sodium nitroprusside in patients undergoing carotid endarterectomy. AANA J 1990; 58: 281–7.Google ScholarPubMed
Kross, RA, Ferri, E, Leung, D et al. A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. Anesth Analg 2000; 91: 904–9.CrossRefGoogle Scholar
Leslie, JB, Kalayjian, RW, Sirgo, MA et al. Intravenous labetalol for treatment of postoperative hypertension. Anesthesiology 1987; 67: 413–16.CrossRefGoogle ScholarPubMed
Malsch, E, Katonah, J, Gratz, I et al. The effectiveness of labetalol in treating post-operative hypertension. Nurse Anesth 1991; 2: 65–71.Google Scholar
Muzzi DA Black, S, Losasso, TJ et al. Labetalol and esmolol in the control of hypertension after intracranial surgery. Anesth Analg 1990; 70: 68–71.Google Scholar
Orlowski, JP, Shiesley, D, Vidt, DG et al. Labetalol to control blood pressure after cerebrovascular surgery. Crit Care Med 1988; 16: 765–8.CrossRefGoogle ScholarPubMed
Orlowski, JP, Vidt, DG, Walker, S et al. The hemodynamic effects of intravenous labetalol for postoperative hypertension. Cleve Clin J Med 1989; 56: 29–34.CrossRefGoogle ScholarPubMed
Prys-Roberts, C, Dagnino, J.Continuous i.v. infusion of labetalol for postoperative hypertension. Br J Anaesth 1988; 60: 600.CrossRefGoogle ScholarPubMed
Singh, PP, Dimich, I, Sampson, I et al. A comparison of esmolol and labetalol for the treatment of perioperative hypertension in geriatric ambulatory surgical patients. Can J Anaesth 1992; 39: 559–62.CrossRefGoogle ScholarPubMed
McCauley, J, Murray, J, Jordan, M et al. Labetalol-induced hyperkalemia in renal transplant recipients. Am J Nephrol 2002; 22: 347–51.CrossRefGoogle ScholarPubMed
Hamad, A, Salameh, M, Zihlif, M et al. Life-threatening hyperkalemia after intravenous labetalol injection for hypertensive emergency in a hemodialysis patient. Am J Nephrol 2001; 21: 241–4.CrossRefGoogle Scholar
Gibson, BE, Black, S, Maass, L et al. Esmolol for the control of hypertension after neurologic surgery. Clin Pharmacol Ther 1988; 44: 650–3.CrossRefGoogle ScholarPubMed
Gray, RJ, Bateman, TM, Czer, LS et al. Comparison of esmolol and nitroprusside for acute post-cardiac surgical hypertension. Am J Cardiol 1987; 59: 887–91.CrossRefGoogle ScholarPubMed
Murphy, MB, Murray, C, Shorten, GD.Fenoldopam: a selective peripheral dopamine-receptor agonist for the treatment of severe hypertension. N Engl J Med 2001; 345: 1548–57.CrossRefGoogle ScholarPubMed
Shusterman, NH, Elliott, WJ, White, WB.Fenoldopam, but not nitroprusside, improves renal function in severely hypertensive patients with impaired renal function. Am J Med 1993; 95: 161–8.CrossRefGoogle Scholar
Elliott, WJ, Weber, RR, Nelson, KS et al. Renal and hemodynamic effects of intravenous fenoldopam versus nitroprusside in severe hypertension. Circulation 1990; 81: 970–7.CrossRefGoogle ScholarPubMed
Goldberg, ME, Clark, S, Joseph, J et al. Nicardipine versus placebo for the treatment of postoperative hypertension. Am Heart J 1990; 119: 446–50.CrossRefGoogle ScholarPubMed
IV Nicardipine Study Group. Efficacy and safety of intravenous nicardipine in the control of postoperative hypertension. Chest 1991; 99: 393–8.CrossRefGoogle Scholar
Halpern, NA, Alicea, M, Krakoff, LR et al. Postoperative hypertension: a prospective, placebo-controlled, randomized, double-blind trial, with intravenous nicardipine hydrochloride. Angiology 1990; 41: 992–1004.Google ScholarPubMed
Halpern, NA, Sladen, RN, Goldberg, JS et al. Nicardipine infusion for postoperative hypertension after surgery of the head and neck. Crit Care Med 1990; 18: 950–5.CrossRefGoogle ScholarPubMed
van Wezel, HB, Koolen, JJ, Visser, CA et al. Antihypertensive and anti-ischemic effects of nicardipine and nitroprusside in patients undergoing coronary artery bypass grafting. Am J Cardiol 1989; 64: 22H–27H.CrossRefGoogle ScholarPubMed
Vincent, JL, Berlot, G, Preiser, JC et al. Intravenous nicardipine in the treatment of postoperative arterial hypertension. J Cardiothorac Vasc Anesth 1997; 11: 160–4.CrossRefGoogle ScholarPubMed
Nguyen, HM, Ma, K, Pham, DQ.Clevidipine for the treatment of severe hypertension in adults. Clin Ther 2010; 32: 11–23.CrossRefGoogle ScholarPubMed
Grossman, E, Messerli, FH, Grodzicki, T et al. Should a moratorium be placed on sublingual nifedipine capsules given for hypertensive emergencies and pseudo-emergencies?J Am Med Assoc 1996; 276: 1328–31.CrossRefGoogle Scholar
Varon, J, Marik, PE.Perioperative hypertension management. Vasc Health Risk Manage 2008; 4: 615–27.CrossRefGoogle ScholarPubMed
Magee, LA, Cham, C, Waterman, EJ et al. Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. Br Med J 2003; 327: 955–65.CrossRefGoogle ScholarPubMed
Basali, A, Mascha, EJ, Kalfas, I et al. Relation between perioperative hypertension and intracranial hemorrhage after craniotomy. Anesthesiology 2000; 93: 48–54.CrossRefGoogle ScholarPubMed
Tohmo, H, Karanko, M.Enalaprilat controls postoperative hypertension while maintaining cardiac function and systemic oxygenation after neurosurgery. Intens Care Med 1995; 21: 651–6.CrossRefGoogle ScholarPubMed
Bekker, A, Didehvar, S, Kim, S et al. Efficacy of clevidipine in controlling postoperative hypertension in neurosurgical patients: initial single-center experience. J Neurosurg Anesth 2010; 22: 330–5.CrossRefGoogle Scholar
Stonham, MD, Thompson, JP.Arterial pressure management and carotid endarterectomy. Br J Anaesth 2009; 102; 442–52.CrossRefGoogle Scholar
Dorman, T, Thompson, DA, Breslow, MJ et al. Nicardipine versus nitroprusside for breakthrough hypertension following carotid endarterectomy. J Clin Anesth 2001; 13: 281–7.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×