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Chapter 2 - Viral Hepatitis

from Section 2 - Infections in Pregnancy

Published online by Cambridge University Press:  11 October 2019

Adel Elkady
Affiliation:
Police Force Hospital, Cairo
Prabha Sinha
Affiliation:
Oman Medical College, Oman
Soad Ali Zaki Hassan
Affiliation:
Alexandria University
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Summary

Viruses are small, non-living parasites, which cannot replicate outside a host cell.

Viruses are grouped according to their genetic material: DNA or RNA.

DNA viruses are mostly double-stranded while RNA viruses are single-stranded.

A virus injects its genetic information into a host cell and then takes control of the cell’s machinery. This process enables the virus to make copies of its DNA or RNA and make the viral proteins inside the host cell. A virus can quickly make multiple copies of itself in one cell, release these copies to infect new host cells and make even more copies. In this way, a virus can replicate very quickly inside a host.

Type
Chapter
Information
Infections in Pregnancy
An Evidence-Based Approach
, pp. 9 - 17
Publisher: Cambridge University Press
Print publication year: 2019

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References

Thompson, N. Differentiating RNA & DNA Viruses. Sciencing. sciencing.com/differentiating-rna-dna-viruses-4853.html.Google Scholar
World Health Organization. WHO Global Hepatitis Report 2017. www.who.int/hepatitis/publications/global-hepatitis-report2017/en/.Google Scholar
World Health Organization. WHO Hepatitis A Fact Sheet July 2017. www.who.int/topics/hepatitis/factsheets/en/.Google Scholar
Lemon, SM. Type A viral hepatitis: epidemiology, diagnosis, and prevention. Clin Chem. 1997; 43(8 Pt 2): 1494–9.CrossRefGoogle ScholarPubMed
World Health Organization. Hepatitis A. Wkly Epidemiol Rec. 2000; 75(5): 3844.Google Scholar
McDuffie, RS, Bader, T. Fetal meconium peritonitis after maternal hepatitis A. Am J Obstet Gynecol. 1999; 180(4): 1031–2.CrossRefGoogle ScholarPubMed
Dandi, N, Shouval, D, Stein, ZC, Ackerman, Z. Breast milk hepatitis A virus in nursing mother with acute hepatitis A infection. Breastfeed Med. 2012; 7: 313–15.Google Scholar
Fawaz, R, Baumann, U, Ekong U, et al. Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. www.naspghan.org/files/documents/pdfs/position-papers/Guideline_for_the_Evaluation_of_Cholestatic.23.pdf.Google Scholar
Daudi, N, Shouval, D, Stein-Zamir, C, Ackerman, Z, Cara, L. Breastmilk hepatitis A virus RNA in nursing mothers with acute hepatitis A virus infection. Breastfeed Med. 2012; 7: 313–15.CrossRefGoogle ScholarPubMed
Fiore, AE, Wasley, A, Bell, BP. Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP0. MMWR Recomm Rep. 2006 19 May. 55(RR-7): 123.Google Scholar
Chaudhry, SA, Koren, G. Hepatitis A infection during pregnancy. Can Fam Physician. 2015 Nov; 61(11): 963–4.Google Scholar
Kao, JH, Chan, DS. Global control of hepatitis B virus infection. Lancet Infect Dis. 2002; 2(7): 395403.CrossRefGoogle ScholarPubMed
Euler, GL, Wooten, KG, Bahghman, AL, William, WW. Hepatitis B surface antigen prevalence among pregnant women in urban areas: implications for testing, reporting and preventing perinatal transmission. Paediatrics. 2003; 111(5 Pt 2): 1192–7.CrossRefGoogle ScholarPubMed
World Health Organization. Hepatitis B key facts. www.who.int/news-room/fact-sheets/detail/hepatitis-b.Google Scholar
Sookoian, S. Liver disease in pregnancy: acute viral hepatitis. Ann Hepatol. 2006; 5: 231.Google Scholar
Jonas, MM. Hepatitis B and pregnancy: an underestimated issue. Liver Int. 2009(suppl 1): 133.CrossRefGoogle Scholar
World Health Organization. WHO Hepatitis B Factsheet July 2017. www.who.int/topics/hepatitis/factsheets/en/.Google Scholar
Visvanathan, K, Dusheiko, G, Giles, M et al. Managing HBV in pregnancy. Prevention, prophylaxis, treatment and follow-up: position paper produced by Australian, UK and New Zealand key opinion leaders. Gut. 2016; 65(2): 340–50.Google Scholar
Antiretroviral Pregnancy Registry. www.apregistry.com.Google Scholar
Munderi, P, Wilkes, H, Tumukunde, D et al. Pregnancy and outcomes among women on triple-drug antiretroviral therapy (ART) in the DART trial (poster WEPEB261). Presented at the Fifth IAS Conference on HIV Pathogenesis, Treatment and Prevention, Cape Town, South Africa, 19–22 July 2009.Google Scholar
Liaw, YF, Leung, N, Guan, R et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2005 update. Liver Int. 2005; 25: 472.CrossRefGoogle ScholarPubMed
Chang, MS, Gavini, S, Andrade, PC, McNabb-Baltar, J. Caesarean section to prevent transmission of hepatitis B: a meta-analysis. Can J Gastroenterol Hepatol. 2014; 28: 439.Google Scholar
Yang, M, Qin, Q, Fang, Q, Jiang, LX, Nie, SF. Cesarean section to prevent mother-to-child transmission of hepatitis B virus in China: a meta-analysis. BMC Pregnancy Childbirth. 2017; 17: 303.Google Scholar
Maheshwari, A, Ray, S, Thuluvath, PJ. Acute hepatitis C. Lancet. 2008; 372(9635): 321–32.Google Scholar
Simmonds, P. Viral heterogeneity of the hepatitis C virus. J Hepatol. 1999; 31(suppl 1): 5460.Google Scholar
Roberts, EA, Yeung, L. Maternal-infant transmission of hepatitis C virus infection. Hepatology. 2002; 36(5 suppl 1): S106–13.Google ScholarPubMed
American College of Obstetricians and Gynecologists. Hepatitis B and Hepatitis C in Pregnancy. FAQ093, November 2013. www.acog.org/Patients/FAQs/Hepatitis-B-and-Hepatitis-C-in-Pregnancy?IsMobileSet=false.Google Scholar
Centers for Disease Control and Prevention. Testing Recommendations for Hepatitis C Virus Infection. 2014. www.cdc.gov/hepatitis/hcv/guidelinesc.htm.Google Scholar
Prasad, MR, Honegger, JR. Hepatitis C virus in pregnancy. Am J Perinatol. 2013; 30(2): 10.1055/s–0033–1334459.Google Scholar
Royal College of Midwives, 2008. Hepatitis C, Position Statement. London: Royal College of Midwives.Google Scholar
Gupta, E, Bajpai, M, Choudhary, A. Hepatitis C virus: screening, diagnosis, and interpretation of laboratory assays. Asian J Transfus Sci. 2014; 8(1): 1925.Google ScholarPubMed
Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report, 2013. www.cdc.gov/mmwr/pdf/wk/mm62e0507a2.pdf.Google Scholar
World Health Organization. Hepatitis D 23 July 2018 Key facts. www.who.int/news-room/fact-sheets/detail/hepatitis-d.Google Scholar
Wedemeyer, H, Manns, MP Epidemiology, pathogenesis and management of hepatitis D: update and challenges ahead. Nat Rev Gastroenterol Hepatol. 2010; 7(1): 3140.CrossRefGoogle ScholarPubMed
World Health Organization. WHO Hepatitis D Fact Sheet July 2017. www.who.int/mediacentre/factsheets/hepatitis-d/en/.Google Scholar
Chaudhry, SA, Verma, N, Koren, GNV. Hepatitis E infection during pregnancy. Can Fam Physician. 2015; 61(7): 607–8.Google ScholarPubMed
WHO Hepatitis E Fact Sheet July 2017. www.who.int/mediacentre/factsheets/fs280/en/.Google Scholar
Patra, S, Kumar, A, Trivedi, SS, Puri, M, Sarin, SK. Maternal and foetal outcomes in pregnant women with acute hepatitis E virus infection. Ann Intern Med. 2007; 147(1): 2833.Google Scholar

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