Book contents
- Fetal Therapy
- Fetal Therapy
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Section 1: General Principles
- Section 2: Fetal Disease: Pathogenesis and Treatment
- Red Cell Alloimmunization
- Structural Heart Disease in the Fetus
- Chapter 12 Structural Heart Disease: Embryology
- Chapter 13 Structural Heart Disease: Genetic Influences
- Chapter 14 Deciphering the Mechanisms of Developmental Heart Disease: Research from Embryonic Knockout Mice
- Chapter 15 In Utero Intervention for Cardiac Disease
- Chapter 16 Fetal Cerebral Consequences of Structural Heart Disease: Can These Be Ameliorated?
- Fetal Dysrhythmias
- Manipulation of Fetal Amniotic Fluid Volume
- Fetal Infections
- Fetal Growth and Well-being
- Preterm Birth of the Singleton and Multiple Pregnancy
- Complications of Monochorionic Multiple Pregnancy: Twin-to-Twin Transfusion Syndrome
- Complications of Monochorionic Multiple Pregnancy: Fetal Growth Restriction in Monochorionic Twins
- Complications of Monochorionic Multiple Pregnancy: Twin Reversed Arterial Perfusion Sequence
- Complications of Monochorionic Multiple Pregnancy: Multifetal Reduction in Multiple Pregnancy
- Fetal Urinary Tract Obstruction
- Pleural Effusion and Pulmonary Pathology
- Surgical Correction of Neural Tube Anomalies
- Fetal Tumors
- Congenital Diaphragmatic Hernia
- Fetal Stem Cell Transplantation
- Gene Therapy
- Section III: The Future
- Index
- References
Chapter 15 - In Utero Intervention for Cardiac Disease
from Structural Heart Disease in the Fetus
Published online by Cambridge University Press: 21 October 2019
Book contents
- Fetal Therapy
- Fetal Therapy
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Section 1: General Principles
- Section 2: Fetal Disease: Pathogenesis and Treatment
- Red Cell Alloimmunization
- Structural Heart Disease in the Fetus
- Chapter 12 Structural Heart Disease: Embryology
- Chapter 13 Structural Heart Disease: Genetic Influences
- Chapter 14 Deciphering the Mechanisms of Developmental Heart Disease: Research from Embryonic Knockout Mice
- Chapter 15 In Utero Intervention for Cardiac Disease
- Chapter 16 Fetal Cerebral Consequences of Structural Heart Disease: Can These Be Ameliorated?
- Fetal Dysrhythmias
- Manipulation of Fetal Amniotic Fluid Volume
- Fetal Infections
- Fetal Growth and Well-being
- Preterm Birth of the Singleton and Multiple Pregnancy
- Complications of Monochorionic Multiple Pregnancy: Twin-to-Twin Transfusion Syndrome
- Complications of Monochorionic Multiple Pregnancy: Fetal Growth Restriction in Monochorionic Twins
- Complications of Monochorionic Multiple Pregnancy: Twin Reversed Arterial Perfusion Sequence
- Complications of Monochorionic Multiple Pregnancy: Multifetal Reduction in Multiple Pregnancy
- Fetal Urinary Tract Obstruction
- Pleural Effusion and Pulmonary Pathology
- Surgical Correction of Neural Tube Anomalies
- Fetal Tumors
- Congenital Diaphragmatic Hernia
- Fetal Stem Cell Transplantation
- Gene Therapy
- Section III: The Future
- Index
- References
Summary
Unlike other fetal therapies, cardiac interventions have not been tested by randomized controlled trials (RCT), such as the one to determine the optimal management of twin-to-twin transfusion syndrome (TTTS) [1]. Most reports of fetal cardiac interventions have no appropriate control subjects and have resulted in level three evidence at best, so their clinical value and generalizability to the fetal population with obstructive cardiac lesions remain uncertain.
- Type
- Chapter
- Information
- Fetal TherapyScientific Basis and Critical Appraisal of Clinical Benefits, pp. 146 - 156Publisher: Cambridge University PressPrint publication year: 2020
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