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Primidone

Published online by Cambridge University Press:  04 August 2010

Philip N. Patsalos
Affiliation:
Chalfont Centre for Epilepsy, Buckinghamshire, UK
Blaise F. D. Bourgeois
Affiliation:
Harvard Medical School, Boston
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Publisher: Cambridge University Press
Print publication year: 2010

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References

Kuhnz, W, Koch, S, Helge, H, Nau, H. Primidone and phenobarbital during lactation period in epileptic women: total and free drug serum levels in the nursed infants and their effects on neonatal behavior. Developmental Pharmacology and Therapeutics 1988; 11: 147–154.CrossRefGoogle ScholarPubMed
Leppik, IE, Cloyd, JC, Miller, K. Development of tolerance to the side effects of primidone. Therapeutic Drug Monitoring 1984; 6: 189–191.CrossRefGoogle ScholarPubMed
Mattson, RH, Cramer, JA, Collins, JF, Smith, DB, Delgado-Escueta, AV, Browne, TR, Williamson, PD, Treiman, DM, McNamara, JO, McCutchen, CB. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. New England Journal of Medicine 1985; 313: 145–151.CrossRefGoogle ScholarPubMed
Nau, H, Rating, D, Hauser, I, Jäger, E, Koch, S, Helge, H. Placental transfer and pharmacokinetics of primidone and its metabolites phenobarbital, PEMA and hydroxyphenobarbital in neonates and infants of epileptic mothers. European Journal of Clinical Pharmacology 1980; 18: 31–42.CrossRefGoogle ScholarPubMed
Patsalos, PN. Anti-epileptic drug interactions. A clinical guide. Clarius Press: Guildford, UK; 2005.Google Scholar
Sapin, JI, Riviello, JJ, Grover, WD. Efficacy of primidone for seizure control in neonates and young infants. Pediatric Neurology 1988; 4: 292–295.CrossRefGoogle ScholarPubMed
Heijst, AN, Jong, W, Seldenrijk, R, Dijk, A. Coma and crystalluria: a massive primidone intoxication treated with haemoperfusion. Journal of Toxicology and Clinical Toxicology 1983; 20: 307–318.Google ScholarPubMed

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