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Chapter 7 - Head Trauma

Published online by Cambridge University Press:  23 August 2019

Alex Koyfman
Affiliation:
University of Texas Southwestern Medical Center
Brit Long
Affiliation:
San Antonio Military Medical Center
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Summary

Head trauma is a significant cause of death around the world, especially in patients 1–45 years old.15 Close to 80% of patients are managed in the emergency department (ED).1.2 Head injury not only causes initial primary injury, but it is associated with several secondary injuries.15

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Publisher: Cambridge University Press
Print publication year: 2019

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References

Faul, M, Xu, L, Wald, MM, et al. Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations and Deaths 2002–2006. Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control; 2010.Google Scholar
Wan-Tsu, WC, Badjatia, N. Neurotrauma. Emerg Med Clin N Am. 2014;32:889905.Google Scholar
Rutland-Brown, W, Langlois, JA, Thomas, KE, Xi, YL. Incidence of traumatic brain injury in the United States, 2003. J Head Trauma Rehabil. 2006;21:544.Google Scholar
Tagliaferri, F, Compagnone, C, Korsic, M, et al. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien). 2006;148:255.Google Scholar
Thurman, DJ, Alverson, C, Dunn, KA, et al. Traumatic brain injury in the United States: a public health perspective. J Head Trauma Rehabil. 1999;14:602.CrossRefGoogle ScholarPubMed
Oddo, M, Le Roux, PD. What is the etiology, pathogenesis and pathophysiology of elevated intracranial pressure? In: Neligan, P, Deutschman, CS, eds. The Evidenced Based Practice of Critical Care. Philadelphia: Elsevier Science; 2009.Google Scholar
Swadron, SP, LeRoux, P, Smith, WS, Weingart, SD. Emergency neurological life support: traumatic brain injury. Neurocrit Care. 2012;17:S112–121.Google Scholar
Barr, RM, Gean, AD, Le, TH. Craniofacial trauma. In: Brant, WE, Helms, CA, eds. Fundamentals of Diagnostic Radiology. Philadelphia: Lippincott, Williams & Wilkins; 2007, p. 69.Google Scholar
Gruen, P. Surgical management of head trauma. Neuroimag Clin N Am. 2002;12(2):339–43.Google Scholar
Smith, J, Tiandra, JJ, Clupie, GJA, Kaye, AH. Textbook of Surgery. Hoboken, NJ: Wiley-Blackwell; 2006, p. 446.Google Scholar
Bouma, GJ, Muizelaar, JP. Cerebral blood flow, cerebral blood volume, and cerebrovascular reactivity after severe head injury. J Neurotrauma. 1992;9(Suppl 1):S333.Google Scholar
Bouma, GJ, Muizelaar, JP, Bandoh, K, Marmarou, A. Blood pressure and intracranial pressure-volume dynamics in severe head injury: relationship with cerebral blood flow. J Neurosurg. 1992;77:15.Google Scholar
Carney, N, Totten, AM, O’Reilly, C, et al. Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery. 2017;80(1):615.Google Scholar
Stevens, RD, Huff, JS, Duckworth, J, et al. Emergency neurological life support: intracranial hypertension and herniation. Neurocrit Care. 2012;17(Suppl 1):S60–65.Google Scholar
Robertson, CS, Valadka, AB, Hannay, HJ, et al. Prevention of secondary ischemic insults after severe head injury. Crit Care Med. 1999;27:2086.Google Scholar
Howells, T, Elf, K, Jones, PA, et al. Pressure reactivity as a guide in the treatment of cerebral perfusion pressure in patients with brain trauma. J Neurosurg. 2005;102:311.CrossRefGoogle ScholarPubMed
Aarabi, B, Tofighi, B, Kufera, JA, et al. Predictors of outcome in civilian gunshot wounds to the head. J Neurosurg. 2014;120(5):1138–46.CrossRefGoogle ScholarPubMed
Magnuson, J, Leonessa, F, Ling, GS. Neuropathology of explosive blast traumatic brain injury. Curr Neurol Neurosci Rep. 2012;12(5):570–79.Google Scholar
Chestnut, RM, Marshall, LF, Klauber, MR, et al. The role of secondary brain injury in determining outcome from severe head injury. J Trauma. 1993;34(2):216–22.Google Scholar
Marmarou, A, Anderson, RL, Ward, JD, et al. Impact of ICP instability and hypotension on outcome in patients with severe head trauma. J Neurosurg. 1991;75(Suppl):S59–66.CrossRefGoogle Scholar
McHugh, GS, Engel, DC, Butcher, I, et al. Prognostic value of secondary insults in traumatic brain injury: results from the IMPACT study. J Neurotrauma. 2007;24:287.Google Scholar
Harhangi, BS, Kompanje, EJ, Leebeek, FW, Maas, AI. Coagulation disorders after traumatic brain injury. Acta Neurochir (Wien). 2008;150:165.Google Scholar
Perkins, ZB, Wittenberg, MD, Nevin, D, et al. The relationship between head injury severity and hemodynamic response to tracheal intubation. J Trauma Acute Care Surg. 2013;74:1074.Google Scholar
Bucher, J, Koyfman, A. Intubation of the neurologically injured patient. JEM. 2015;49(6):920–27.Google Scholar
Chang, EF, Meeker, M, Holland, MC. Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period. Neurosurgery. 2006;58:647.CrossRefGoogle ScholarPubMed
Oertel, M, Kelly, DF, McArthur, D, et al. Progressive hemorrhage after head trauma: predictors and consequences of the evolving injury. J Neurosurg. 2002;96:109.Google Scholar
Narayan, RK, Maas, AI, Servadei, F, et al. Progression of traumatic intracerebral hemorrhage: a prospective observational study. J Neurotrauma. 2008;25:629.Google Scholar
Weingart, SD, Levitan, RM. Preoxygenation and prevention of desaturation during emergency airway management. Ann Emerg Med. 2012;59:165–175.e1.Google Scholar
Dixon, BJ, Dixon, JB, Carden, JR, et al. Preoxygenation is more effective in the 25 degrees head-up position than in the supine position in severely obese patients: a randomized controlled study. Anesthesiology. 2005;102:1110–15, discussion 1115A.Google Scholar
Robinson, N, Clancy, M. In patients with head injury undergoing rapid sequence intubation, does pretreatment with intravenous lignocaine/lidocaine lead to an improved neurological outcome? A review of the literature. Emerg Med J. 2001;18(6):453–57.CrossRefGoogle Scholar
Ugur, B, Ogurlu, M, Gezer, E, et al. Effects of esmolol, lidocaine and fentanyl on haemodynamic responses to endotracheal intubation: a comparative study. Clin Drug Invest. 2007;27: 269–77.Google Scholar
Seder, DB, Riker, RR, Jagoda, A, Smith, WS, Weingart, SD. Emergency neurological life support: airway, ventilation, and sedation. Neurocrit Care. 2010;17:S4–20.Google Scholar
Cohen, L, Athaide, V, Wickham, ME, et al. The effect of ketamine on intracranial and cerebral perfusion pressure and health outcomes: a systematic review. Ann Emerg Med. 2015;65:4351.CrossRefGoogle ScholarPubMed
Moss, E, Powell, D, Gibson, RM, McDowall, DG. Effect of etomidate on intracranial pressure and cerebral perfusion pressure. Br J Anaesth. 1979;51:347–52.Google Scholar
Rossaint, J, Rossaint, R, Weis, J, et al. Propofol: neuroprotection in an in vitro model of traumatic brain injury. Crit Care. 2009;13:R61.Google Scholar
Hug, CC Jr, McLeskey, CH, Nahrwold, ML, et al. Hemodynamic effects of propofol: data from over 25,000 patients. Anesth Analg. 1993;77:S21–29.Google Scholar
Kovarik, WD, Mayberg, TS, Lam, AM, et al. Succinylcholine does not change intracranial pressure, cerebral blood flow velocity, or the electroencephalogram in patients with neurologic injury. Anesth Analg. 1994;78:469–73.Google Scholar
Brown, MM, Parr, MJ, Manara, AR. The effect of suxamethonium on intracranial pressure and cerebral perfusion pressure in patients with severe head injuries following blunt trauma. Eur J Anaesthesiol. 1996;13:474–77.Google Scholar
Koenig, KL. Rapid-sequence intubation of head trauma patients: prevention of fasciculations with pancuronium versus minidose succinylcholine. Ann Emerg Med. 1992;21:929–32.Google Scholar
Otterspoor, LC, Kalkman, CJ, Cremer, OL. Update on the propofol infusion syndrome in ICU management of patients with head injury. Curr Opin Anaesthesiol. 2008;21:544.Google Scholar
Jakob, SM, Ruokonen, E, Grounds, RM, et al. Dexmedetomidine vs. midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA. 2012;307:1151–60.Google Scholar
Weingart, S. EMCrit: Podcast 78 – Increased intra-cranial pressure (ICP) and herniation, aka brain code. Available at: http://emcrit.org/podcasts/high-icp-herniation/. Accessed November 16, 2016.Google Scholar
Berry, C, Ley, EJ, Bukur, M, et al. Redefining hypotension in traumatic brain injury. Injury. 2012;43(11):1833–37.CrossRefGoogle ScholarPubMed
Brenner, M, Stein, DM, Hu, PF, et al. Traditional systolic blood pressure targets underestimate hypotension-induced secondary brain injury. J Trauma Acute Care Surg. 2012;72(5):1135–39.Google Scholar
Butcher, I, Murray, GD, McHugh, GS, et al. Multivariable prognostic analysis in traumatic brain injury: results from the IMPACT study. J Neurotrauma. 2007;24(2):329–37.Google Scholar
ATLS Subcommittee; American College of Surgeons’ Committee on Trauma; International ATLS working group. Advanced trauma life support (ATLS®): the ninth edition. J Trauma Acute Care Surg. 2013;74(5):1363–66.Google Scholar
Hadley, MN, Walters, BC, Grabb, PA, et al. Blood pressure management after acute spinal cord injury. Neurosurgery. 2002;50:S58–62.Google Scholar
Guidelines for the management of acute cervical spine and spinal cord injuries: Available at: www.aans.org/en/Education%20and%20Meetings/*/media/Files/Education%20and%20Meetingf/Clinical%20Guidelines/TraumaGuidelines.ashx. 2007. Accessed May, 2016.Google Scholar
Boone, MD, Oren-Grinberg, A, Robinson, TM, et al. Mannitol or hypertonic saline in the setting of traumatic brain injury: what have we learned? Surg Neurol Int. 2015;6:177.Google Scholar
Freshman, S, Battistella, F, Matteucci, M, et al. Hypertonic saline (7.5%) versus mannitol: a comparison for treatment of acute head injuries. J Trauma. 1993;35(3):344–48.Google Scholar
Thenuwara, K, Todd, MM, Brian, JE. Effect of mannitol and furosemide on plasma osmolality and brain water. Anesthesiology. 2002;96(2):416–21.Google Scholar
Wang, LC, Papangelou, A, Lin, C, et al. Comparison of equivolume, equiosmolar solutions of mannitol and hypertonic saline with or without furosemide on brain water content in normal rats. Anesthesiology. 2013;118(4):903–13.Google Scholar
Scalfani, M, Dhar, R, Zazulia, A, et al. Effect of osmotic agents on regional blood flow in traumatic brain injury. J Crit Care. 2012;27(5):526.e7–1.Google Scholar
Battison, C, Andrews, PJ, Graham, C, Petty, T. Randomized, controlled trial on the effect of a 20% mannitol solution and a 7.5% saline/6% dextran solution on increased intracranial pressure after brain injury. Crit Care Med. 2005;33:196.Google Scholar
Vialet, R, Albanèse, J, Thomachot, L, et al. Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 mL/kg 7.5% saline is more effective than 2 mL/kg 20% mannitol. Crit Care Med. 2003;31:1683.Google Scholar
Muizelaar, JP, Wei, EP, Kontos, HA, et al. Mannitol causes compensatory cerebral vasoconstriction and vasodilation in response to blood viscosity changes. J Neurosurg. 1983;59(5):822–28.Google Scholar
Palma, L, Bruni, G, Fiaschi, A, et al. Passage of mannitol into the brain around gliomas: a potential cause of rebound phenomenon. A study on 21 patients. J Neurosurg Sci. 2006;50(3):6366.Google Scholar
Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, et al. Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J Neurotrauma. 2007;24(Suppl 1);S37.Google Scholar
Narayan, RK, Kishore, PR, Becker, DP, et al. Intracranial pressure: to monitor or not to monitor? J Neurosurg. 1982;56(56):650–59.Google Scholar
Potgieter, DW, Kippin, A, Ngu, F, McKean, C. Can accurate ultrasonographic measurement of the optic nerve sheath diameter (a non-invasive measure of intracranial pressure) be taught to novice operators in a single training session? Anaesth Intensive Care. 2011;39(1):95100.CrossRefGoogle Scholar
Sekhon, MS, McBeth, P, Zou, J, et al. Association between optic nerve sheath diameter and mortality in patients with severe traumatic brain injury. Neurocrit Care. 2014;21(2):245–52.Google Scholar
Hassen, GW, Bruck, I, Donahue, J, et al. Accuracy of optic nerve sheath diameter measurement by emergency physicians using bedside ultrasound. J Emerg Med. 2015;48(4):450–57.Google Scholar
Cooper, DJ, Rosenfeld, JV, Murray, L, et al. Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med. 2011;364(16):1493–502.Google Scholar
Honeybul, S, Ho, KM, Lind, CR. What can be learned from the DECRA study. World Neurosurg. 2013;79(1):159–61.Google Scholar
Fehlings, MG, Vaccaro, A, Wilson, JR, et al. Early versus delayed decompression for traumatic cervical spinal cord injury: results of the surgical timing in acute spinal cord injury study (STASCIS). PLoS One. 2012;7(2):e32037.Google Scholar
Hutchinson, PJ, Kolias, AG, Timofeev, IS, et al. Trial of decompressive craniectomy for traumatic intracranial hypertension. N Engl J Med. 2016;375(12):1119–30.Google Scholar
Bullock, MR, Chestnut, R, Ghajar, J, et al. Guidelines for the surgical management of traumatic brain injury. Neurosurgery. 2006;58(Suppl):S2–1–3.Google Scholar
Morgenstern, LB, Hemphill, JC 3rd, Anderson, C, et al. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010;41:2108.Google Scholar
Manno, EM, Atkinson, JL, Fulgham, JR, et al. Emerging medical and surgical management strategies in the evaluation and treatment of intracerebral hemorrhage. Mayo Clin Proc. 2005;80:420.Google Scholar
Eller, T, Busse, J, Dittrich, M, et al. Dabigatran, rivaroxaban, apixaban, argatroban and fondaparinux and their effects on coagulation POC and platelet function tests. Clin Chem Lab Med. 2014;52:835.Google Scholar
Dickneite, G, Hoffman, M. Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence? Thromb Haemost. 2014;111:189.Google Scholar
Baharoglu, MI, Cordonnier, C, Al-Shahi Salman, R, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial. Lancet. 2016;387(10038):2605–13.Google Scholar
Inaba, K, Menaker, J, Branco, BC, et al. A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis. J Trauma Acute Care Surg. 2013;74(3):766–71, discussion: 771–73.Google Scholar
Torbic, H, Forni, A, Anger, KE, et al. Use of antiepileptics for seizure prophylaxis after traumatic brain injury. Am J Heal Pharm. 2013;70(9):759–66.Google Scholar
Morrison, JJ, Dubose, JJ, Rasmussen, TE, Midwinter, MJ. Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) study. Arch Surg. 2012;147(2):113–19.Google Scholar
Perel, P, Al-Shahi Salman, R, Kawahara, T, et al. CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury – a nested randomised, placebo-controlled trial. Health Technol Assess. 2012;16(13):iiixii, 1–54.Google Scholar
Roberts, I, Shakur, H, Coats, T, et al. The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health Technol Assess. 2013;17(10):179.Google Scholar
Dewan, Y, Komolafe, EO, Mejía-Mantilla, JH, et al. CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial. Trials. 2012;13:87.Google Scholar
Sydenham, E, Roberts, I, Alderson, P. Hypothermia for traumatic head injury. Cochrane Database Syst Rev, 2009;(2):CD00104.Google Scholar
Peterson, K, Carson, S, Carney, N. Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis. J Neurotrauma. 2008;25(1):6271.CrossRefGoogle ScholarPubMed
Roberts, I, Sydenham, E. Barbiturates for acute traumatic brain injury. Cochrane Database Syst Rev. 2012;(12):CD000033.Google Scholar

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