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Chapter 16 - Assisted Conception Techniques

from Section 3 - Reproductive Endocrinology and Infertility

Published online by Cambridge University Press:  24 November 2021

By
Antonios Makrigiannakis  and
Panagiotis Drakopoulos
Edited by
Tahir Mahmood ,
Charles Savona-Ventura ,
Ioannis Messinis  and
Sambit Mukhopadhyay
Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona-Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Failure to conceive following 12 months of unprotected intercourse is defined as infertility. Both male and female factors can lead to infertility. Various forms of assisted reproductive techniques with different success rates are available to manage both male and female infertility. In some clearly defined cases gestational surrogacy provides the only hope for a couple to have their own genetic children.

Keywords

IVFcontrolled ovarian stimulation (COS)IUIICSIsurrogacy
Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Gynaecology
 , pp. 135 - 138
Publisher: Cambridge University Press
Print publication year: 2021

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References

Zegers-Hochschild, F, Adamson, GD, Dyer, S, et al. The international glossary on infertility and fertility care, 2017. Fertil Steril 2017;108:393–406.Google Scholar
Jose-Miller, AB, Boyden, JW, Frey, KA. Infertility. Am Fam Physician 2007;75:849–856.Google ScholarPubMed
Group ECW. Intrauterine insemination. Hum Reprod Update 2009;15:265–277.CrossRefGoogle Scholar
Mankus, EB, Holden, AE, Seeker, PM, et al. Prewash total motile count is a poor predictor of live birth in intrauterine insemination cycles. Fertil Steril 2019;111:708–713.CrossRefGoogle ScholarPubMed
De Geyter, C, Calhaz-Jorge, C, Kupka, MS, et al. ART in Europe, 2014: results generated from European registries by ESHRE: the European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod 2018;33:1586–1601.CrossRefGoogle ScholarPubMed
Steptoe, PC, Edwards, RG. Birth after the reimplantation of a human embryo. Lancet 1978;2:366.CrossRefGoogle ScholarPubMed
Palermo, G, Joris, H, Devroey, P, Van Steirteghem, AC. Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 1992;340:17–18.Google Scholar
Trounson, AO, Leeton, JF, Wood, C, Webb, J, Wood, J. Pregnancies in humans by fertilization in vitro and embryo transfer in the controlled ovulatory cycle. Science 1981;212:681–682.CrossRefGoogle ScholarPubMed
Edwards, RG, Steptoe, PC, Purdy, JM. Establishing full-term human pregnancies using cleaving embryos grown in vitro. Br J Obstet Gynaecol 1980;87:737–756.CrossRefGoogle ScholarPubMed
Macklon, NS, Stouffer, RL, Giudice, LC, Fauser, BC. The science behind 25 years of ovarian stimulation for in vitro fertilization. Endocr Rev 2006;27:170–207.CrossRefGoogle ScholarPubMed
Gemzell, CA. Induction of ovulation with human pituitary gonadotrophins. Fertil Steril 1962;13:153–168.Google Scholar
Lunenfeld, B. Historical perspectives in gonadotrophin therapy. Hum Reprod Update 2004;10:453–467.CrossRefGoogle ScholarPubMed
Howles, CM. Genetic engineering of human FSH (Gonal-F). Hum Reprod Update 1996;2:172–191.Google Scholar
Porter, RN, Smith, W, Craft, IL, Abdulwahid, NA, Jacobs, HS. Induction of ovulation for in-vitro fertilisation using buserelin and gonadotropins. Lancet 1984;2:1284–1285.Google Scholar
Huirne, JA, Lambalk, CB. Gonadotropin-releasing-hormone-receptor antagonists. Lancet 2001;358:1793–1803.Google Scholar
Al-Inany, HG, Youssef, MA, Ayeleke, RO, et al. Gonadotrophin-releasing hormone antagonists for assisted reproductive technology. Cochrane Database Syst Rev 2016;4:CD001750.Google ScholarPubMed
Lambalk, CB, Banga, FR, Huirne, JA, et al. GnRH antagonist versus long agonist protocols in IVF: a systematic review and meta-analysis accounting for patient type. Hum Reprod Update 2017;23:560–579.CrossRefGoogle ScholarPubMed
Wong, KM, Mastenbroek, S, Repping, S. Cryopreservation of human embryos and its contribution to in vitro fertilization success rates. Fertil Steril 2014;102:19–26.CrossRefGoogle ScholarPubMed
Groenewoud, ER, Macklon, NS, Cohlen, BJ, et al. Cryo-thawed embryo transfer: natural versus artificial cycle: A non-inferiority trial (ANTARCTICA trial). BMC Women Health 2012;12:27.Google Scholar
Groenewoud, ER, Cantineau, AE, Kollen, BJ, Macklon, NS, Cohlen, BJ. What is the optimal means of preparing the endometrium in frozen-thawed embryo transfer cycles? A systematic review and meta-analysis. Hum Reprod Update 2013;19:458–470.Google Scholar
Maheshwari, A, McLernon, D, Bhattacharya, S. Cumulative live birth rate: time for a consensus? Hum Reprod 2015;30:2703–2707.Google ScholarPubMed
Franasiak, JM, Forman, EJ, Hong, KH, et al. The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening. Fertil Steril 2014;101:656–663 e1.Google Scholar
Mastenbroek, S, Twisk, M, van der Veen, F, Repping, S. Preimplantation genetic screening: a systematic review and meta-analysis of RCTs. Hum Reprod Update 2011;17:454–466.Google Scholar
Kang, HJ, Melnick, AP, Stewart, JD, Xu, K, Rosenwaks, Z. Preimplantation genetic screening: who benefits? Fertil Steril 2016;106:597–602.CrossRefGoogle ScholarPubMed
Tal, R, Seifer, DB. Ovarian reserve testing: a user’s guide. Am J Obstet Gynecol 2017;217:129–140.CrossRefGoogle ScholarPubMed
Broer, SL, Broekmans, FJ, Laven, JS, Fauser, BC. Anti-Mullerian hormone: ovarian reserve testing and its potential clinical implications. Hum Reprod Update 2014;20:688–701.Google Scholar
La Marca, A, Sighinolfi, G, Radi, D, et al. Anti-Mullerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART). Hum Reprod Update 2010;16:113–130.CrossRefGoogle ScholarPubMed
La Marca, A, Stabile, G, Artenisio, AC, Volpe, A. Serum anti-Mullerian hormone throughout the human menstrual cycle. Hum Reprod 2006;21:3103–3107.Google Scholar
Broekmans, FJ, de Ziegler, D, Howles, CM, et al. The antral follicle count: practical recommendations for better standardization. Fertil Steril 2010;94:1044–1051.Google Scholar
Weenen, C, Laven, JS, Von Bergh, AR, et al. Anti-Mullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod 2004;10:77–83.CrossRefGoogle ScholarPubMed
Melnick, AP, Rosenwaks, Z. Oocyte donation: insights gleaned and future challenges. Fertil Steril 2018;110:988–993.Google Scholar
Brinsden, PR. Gestational surrogacy. Hum Reprod Update 2003;9:483–491.CrossRefGoogle ScholarPubMed

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