Book contents
- Frontmatter
- Introduction
- Part I Medicine and Disease: An Overview
- Part II Changing Concepts of Health and Disease
- Part III Medical Specialties and Disease Prevention
- Part IV Measuring Health
- Part V The History of Human Disease in the World Outside Asia
- Part VI The History of Human Disease in Asia
- Part VII The Geography of Human Disease
- Part VIII Major Human Diseases Past and Present
- VIII.1 Acquired Immune Deficiency Syndrome (AIDS)
- VIII.2 African Trypanosomiasis (Sleeping Sickness)
- VIII.3 Ainhum
- VIII.4 Alzheimer’s Disease
- VIII.5 Amebic Dysentery
- VIII.6 Anemia
- VIII.7 Anorexia Nervosa
- VIII.8 Anthrax
- VIII.9 Apoplexy and Stroke
- VIII.10 Arboviruses
- VIII.11 Arenaviruses
- VIII.12 Arthritis (Rheumatoid)
- VIII.13 Ascariasis
- VIII.14 Bacillary Dysentery
- VIII.15 Beriberi
- VIII.16 Black Death
- VIII.17 Black and Brown Lung Disease
- VIII.18 Bleeding Disorders
- VIII.19 Botulism
- VIII.20 Brucellosis
- VIII.21 Bubonic Plague
- VIII.22 Carrión’s Disease
- VIII.23 Catarrh
- VIII.24 Cestode Infections
- VIII.25 Chagas’ Disease
- VIII.26 Chlorosis
- VIII.27 Cholera
- VIII.28 Cirrhosis
- VIII.29 Clonorchiasis
- VIII.30 Croup
- VIII.31 Cystic Fibrosis
- VIII.32 Cytomegalovirus Infection
- VIII.33 Dengue
- VIII.34 Diabetes
- VIII.35 Diarrheal Diseases (Acute)
- VIII.36 Diphtheria
- VIII.37 Down Syndrome
- VIII.38 Dracunculiasis
- VIII.39 Dropsy
- VIII.40 Dysentery
- VIII.41 Dyspepsia
- VIII.42 Ebola Virus Disease
- VIII.43 Echinococcosis (Hydatidosis)
- VIII.44 Eclampsia
- VIII.45 Emphysema
- VIII.46 Encephalitis Lethargica
- VIII.47 Enterobiasis
- VIII.48 Epilepsy
- VIII.49 Ergotism
- VIII.50 Erysipelas
- VIII.51 Fascioliasis
- VIII.52 Fasciolopsiasis
- VIII.53 Favism
- VIII.54 Filariasis
- VIII.55 Fungus Infections (Mycoses)
- VIII.56 Fungus Poisoning
- VIII.57 Gallstones (Cholelithiasis)
- VIII.58 Gangrene
- VIII.59 Giardiasis
- VIII.60 Glomerulonephritis (Bright’s Disease)
- VIII.61 Goiter
- VIII.62 Gonorrhea
- VIII.63 Gout
- VIII.64 Herpes Simplex
- VIII.65 Herpesviruses
- VIII.66 Histoplasmosis
- VIII.67 Hookworm Disease
- VIII.68 Huntington’s Disease (Chorea)
- VIII.69 Hypertension
- VIII.70 Infectious Hepatitis
- VIII.71 Infectious Mononucleosis
- VIII.72 Inflammatory Bowel Disease
- VIII.73 Influenza
- VIII.74 Japanese B Encephalitis
- VIII.75 Lactose Intolerance and Malabsorption
- VIII.76 Lassa Fever
- VIII.77 Lead Poisoning
- VIII.78 Legionnaires’ Disease
- VIII.79 Leishmaniasis
- VIII.80 Leprosy
- VIII.81 Leptospirosis
- VIII.82 Leukemia
- VIII.83 Lupus Erythematosus
- VIII.84 Lyme Borreliosis (Lyme Disease)
- VIII.85 Malaria
- VIII.86 Marburg Virus Disease
- VIII.87 Mastoiditis
- VIII.88 Measles
- VIII.89 Meningitis
- VIII.90 Milk Sickness (Tremetol Poisoning)
- VIII.91 Multiple Sclerosis
- VIII.92 Mumps
- VIII.93 Muscular Dystrophy
- VIII.94 Myasthenia Gravis
- VIII.95 Nematode Infections
- VIII.96 Onchocerciasis
- VIII.97 Ophthalmia (Conjunctivitis and Trachoma)
- VIII.98 Osteoarthritis
- VIII.99 Osteoporosis
- VIII.100 Paget’s Disease of Bone
- VIII.101 Paragonimiasis
- VIII.102 Parkinson’s Disease
- VIII.103 Pellagra
- VIII.104 Periodontal Disease (Pyorrhea)
- VIII.105 Pica
- VIII.106 Pinta
- VIII.107 Plague of Athens
- VIII.108 Pneumocystis Pneumonia (Interstitial Plasma Cell Pneumonia, Pneumocystosis)
- VIII.109 Pneumonia
- VIII.110 Poliomyelitis
- VIII.111 Protein-Energy Malnutrition
- VIII.112 Protozoan Infections
- VIII.113 Puerperal Fever
- VIII.114 Q Fever
- VIII.115 Rabies
- VIII.116 Relapsing Fever
- VIII.117 Rheumatic Fever and Rheumatic Heart Disease
- VIII.118 Rickets and Osteomalacia
- VIII.119 Rickettsial Diseases
- VIII.120 Rocky Mountain Spotted Fever and the Spotted Fever Group Diseases
- VIII.121 Rubella
- VIII.122 St. Anthony’s Fire
- VIII.123 Scarlet Fever
- VIII.124 Schistosomiasis
- VIII.125 Scrofula (Scrophula)
- VIII.126 Scurvy
- VIII.127 Sickle-Cell Anemia
- VIII.128 Smallpox
- VIII.129 Streptococcal Diseases
- VIII.130 Strongyloidiasis
- VIII.131 Sudden Infant Death Syndrome
- VIII.132 Sudden Unexplained Death Syndrome (Asian)
- VIII.133 Sweating Sickness
- VIII.134 Syphilis
- VIII.135 Syphilis, Nonvenereal
- VIII.136 Tapeworm
- VIII.137 Tay-Sachs Disease
- VIII.138 Tetanus
- VIII.139 Tetanus, Neonatal
- VIII.140 Tetany
- VIII.141 Toxoplasmosis
- VIII.142 Trematode Infections
- VIII.143 Trench Fever
- VIII.144 The Treponematoses
- VIII.145 Trichinosis
- VIII.146 Trichuriasis
- VIII.147 Tuberculosis
- VIII.148 Tularemia
- VIII.149 Typhoid Fever
- VIII.150 Typhomalarial Fever
- VIII.151 Typhus, Epidemic
- VIII.152 Typhus, Murine
- VIII.153 Typhus, Scrub (Tsutsugamushi)
- VIII.154 Urolithiasis (Renal and Urinary Bladder Stone Disease)
- VIII.155 Varicella Zoster
- VIII.156 Whooping Cough
- VIII.157 Yaws
- VIII.158 Yellow Fever
- Indexes
- References
VIII.6 - Anemia
from Part VIII - Major Human Diseases Past and Present
Published online by Cambridge University Press: 28 March 2008
- Frontmatter
- Introduction
- Part I Medicine and Disease: An Overview
- Part II Changing Concepts of Health and Disease
- Part III Medical Specialties and Disease Prevention
- Part IV Measuring Health
- Part V The History of Human Disease in the World Outside Asia
- Part VI The History of Human Disease in Asia
- Part VII The Geography of Human Disease
- Part VIII Major Human Diseases Past and Present
- VIII.1 Acquired Immune Deficiency Syndrome (AIDS)
- VIII.2 African Trypanosomiasis (Sleeping Sickness)
- VIII.3 Ainhum
- VIII.4 Alzheimer’s Disease
- VIII.5 Amebic Dysentery
- VIII.6 Anemia
- VIII.7 Anorexia Nervosa
- VIII.8 Anthrax
- VIII.9 Apoplexy and Stroke
- VIII.10 Arboviruses
- VIII.11 Arenaviruses
- VIII.12 Arthritis (Rheumatoid)
- VIII.13 Ascariasis
- VIII.14 Bacillary Dysentery
- VIII.15 Beriberi
- VIII.16 Black Death
- VIII.17 Black and Brown Lung Disease
- VIII.18 Bleeding Disorders
- VIII.19 Botulism
- VIII.20 Brucellosis
- VIII.21 Bubonic Plague
- VIII.22 Carrión’s Disease
- VIII.23 Catarrh
- VIII.24 Cestode Infections
- VIII.25 Chagas’ Disease
- VIII.26 Chlorosis
- VIII.27 Cholera
- VIII.28 Cirrhosis
- VIII.29 Clonorchiasis
- VIII.30 Croup
- VIII.31 Cystic Fibrosis
- VIII.32 Cytomegalovirus Infection
- VIII.33 Dengue
- VIII.34 Diabetes
- VIII.35 Diarrheal Diseases (Acute)
- VIII.36 Diphtheria
- VIII.37 Down Syndrome
- VIII.38 Dracunculiasis
- VIII.39 Dropsy
- VIII.40 Dysentery
- VIII.41 Dyspepsia
- VIII.42 Ebola Virus Disease
- VIII.43 Echinococcosis (Hydatidosis)
- VIII.44 Eclampsia
- VIII.45 Emphysema
- VIII.46 Encephalitis Lethargica
- VIII.47 Enterobiasis
- VIII.48 Epilepsy
- VIII.49 Ergotism
- VIII.50 Erysipelas
- VIII.51 Fascioliasis
- VIII.52 Fasciolopsiasis
- VIII.53 Favism
- VIII.54 Filariasis
- VIII.55 Fungus Infections (Mycoses)
- VIII.56 Fungus Poisoning
- VIII.57 Gallstones (Cholelithiasis)
- VIII.58 Gangrene
- VIII.59 Giardiasis
- VIII.60 Glomerulonephritis (Bright’s Disease)
- VIII.61 Goiter
- VIII.62 Gonorrhea
- VIII.63 Gout
- VIII.64 Herpes Simplex
- VIII.65 Herpesviruses
- VIII.66 Histoplasmosis
- VIII.67 Hookworm Disease
- VIII.68 Huntington’s Disease (Chorea)
- VIII.69 Hypertension
- VIII.70 Infectious Hepatitis
- VIII.71 Infectious Mononucleosis
- VIII.72 Inflammatory Bowel Disease
- VIII.73 Influenza
- VIII.74 Japanese B Encephalitis
- VIII.75 Lactose Intolerance and Malabsorption
- VIII.76 Lassa Fever
- VIII.77 Lead Poisoning
- VIII.78 Legionnaires’ Disease
- VIII.79 Leishmaniasis
- VIII.80 Leprosy
- VIII.81 Leptospirosis
- VIII.82 Leukemia
- VIII.83 Lupus Erythematosus
- VIII.84 Lyme Borreliosis (Lyme Disease)
- VIII.85 Malaria
- VIII.86 Marburg Virus Disease
- VIII.87 Mastoiditis
- VIII.88 Measles
- VIII.89 Meningitis
- VIII.90 Milk Sickness (Tremetol Poisoning)
- VIII.91 Multiple Sclerosis
- VIII.92 Mumps
- VIII.93 Muscular Dystrophy
- VIII.94 Myasthenia Gravis
- VIII.95 Nematode Infections
- VIII.96 Onchocerciasis
- VIII.97 Ophthalmia (Conjunctivitis and Trachoma)
- VIII.98 Osteoarthritis
- VIII.99 Osteoporosis
- VIII.100 Paget’s Disease of Bone
- VIII.101 Paragonimiasis
- VIII.102 Parkinson’s Disease
- VIII.103 Pellagra
- VIII.104 Periodontal Disease (Pyorrhea)
- VIII.105 Pica
- VIII.106 Pinta
- VIII.107 Plague of Athens
- VIII.108 Pneumocystis Pneumonia (Interstitial Plasma Cell Pneumonia, Pneumocystosis)
- VIII.109 Pneumonia
- VIII.110 Poliomyelitis
- VIII.111 Protein-Energy Malnutrition
- VIII.112 Protozoan Infections
- VIII.113 Puerperal Fever
- VIII.114 Q Fever
- VIII.115 Rabies
- VIII.116 Relapsing Fever
- VIII.117 Rheumatic Fever and Rheumatic Heart Disease
- VIII.118 Rickets and Osteomalacia
- VIII.119 Rickettsial Diseases
- VIII.120 Rocky Mountain Spotted Fever and the Spotted Fever Group Diseases
- VIII.121 Rubella
- VIII.122 St. Anthony’s Fire
- VIII.123 Scarlet Fever
- VIII.124 Schistosomiasis
- VIII.125 Scrofula (Scrophula)
- VIII.126 Scurvy
- VIII.127 Sickle-Cell Anemia
- VIII.128 Smallpox
- VIII.129 Streptococcal Diseases
- VIII.130 Strongyloidiasis
- VIII.131 Sudden Infant Death Syndrome
- VIII.132 Sudden Unexplained Death Syndrome (Asian)
- VIII.133 Sweating Sickness
- VIII.134 Syphilis
- VIII.135 Syphilis, Nonvenereal
- VIII.136 Tapeworm
- VIII.137 Tay-Sachs Disease
- VIII.138 Tetanus
- VIII.139 Tetanus, Neonatal
- VIII.140 Tetany
- VIII.141 Toxoplasmosis
- VIII.142 Trematode Infections
- VIII.143 Trench Fever
- VIII.144 The Treponematoses
- VIII.145 Trichinosis
- VIII.146 Trichuriasis
- VIII.147 Tuberculosis
- VIII.148 Tularemia
- VIII.149 Typhoid Fever
- VIII.150 Typhomalarial Fever
- VIII.151 Typhus, Epidemic
- VIII.152 Typhus, Murine
- VIII.153 Typhus, Scrub (Tsutsugamushi)
- VIII.154 Urolithiasis (Renal and Urinary Bladder Stone Disease)
- VIII.155 Varicella Zoster
- VIII.156 Whooping Cough
- VIII.157 Yaws
- VIII.158 Yellow Fever
- Indexes
- References
Summary
Anemia, an insufficiency of red blood cells (RBC) and hemoglobin for oxygen-carrying needs, results from a variety of disease processes, some of which must have existed since ancient times. It was defined in quantitative terms in the mid-nineteenth century, but before that the evidence of anemia is found in the descriptions of pallor or in the occurrence of diseases that we now know cause anemia. For example, lead poisoning decreases RBC production and was apparently widespread in Rome. Intestinal parasites cause iron deficiency anemia and were known to exist in ancient times. Parasites found in paleopathological specimens include Ascaris lumbricoides, Trichiuris trichiuria, and various species of Taenia (ovis, globosa, solium, and saginata), all of which can cause intestinal blood loss and anemia. Diphyllobothrium latum, which leads to malabsorption of vitamin B12 and a megaloblastic anemia, has been found in mummies in Prussia and Peru.
Congenital abnormalities in RBC metabolism, including glucose 6-phosphate dehydrogenase (G6PD) deficiency and various forms of thalassemia and sickle-cell disease, were probably present also in ancient times. Thalassemia protects against malaria, and the incidence of the relatively mild, heterozygotic form of thalassemia (thalassemia minor) probably increased in the Mediterranean region after the appearance of falciparum malaria, the most fatal form of the disease.
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- The Cambridge World History of Human Disease , pp. 571 - 577Publisher: Cambridge University PressPrint publication year: 1993