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Chapter 57 - Cardiac Muscle

from Section 4 - Neurophysiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Summary

The primary function of the heart is ejection of blood into the vascular system. Individual cardiomyocytes are specialised in the generation of spontaneous activity (automaticity), transmission of the resulting excitable activity and contraction in response to such excitation.

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Chapter
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Basic Physiology for Anaesthetists , pp. 252 - 261
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Keynes, R. D., Aidley, D. J., Huang, C. L.-H.. Nerve and Muscle, 4th edition. Cambridge, Cambridge University Press, 2011.CrossRefGoogle Scholar
Litonius, E., Tarkkila, P., Neuvonen, P. J., et al. Effect of intravenous lipid emulsion on bupivacaine plasma concentration in humans. Anaesthesia 2012; 67(6): 600–5.CrossRefGoogle ScholarPubMed
Stone, M. E., Salter, B., Fischer, A.. Perioperative management of patients with cardiac implantable electronic devices. Br J Anaesth 2011; 107(Suppl. 1): i16–26.CrossRefGoogle ScholarPubMed
AAGBI Safety Guideline. Management of Severe Local Anaesthetic Toxicity, Association of Anaesthetists of Great Britain and Ireland, 2010; www.aagbi.org/sites/default/files/la_toxicity_2010_0.pdf.Google Scholar
Pinnell, J., Turner, S., Howell, S.. Cardiac muscle physiology. Continuing Educ Anaesth Crit Care Pain 2007; 7(3): 85–8.CrossRefGoogle Scholar
Dippenaar, J. M.. Local anaesthetic toxicity. S Afr J Anaesth Analges 2007; 13(3): 23–8.Google Scholar
Rohr, S.. Role of gap junctions in the propagation of the cardiac action potential. Cardiovasc Res 2004; 62(2): 309–22.CrossRefGoogle ScholarPubMed
Morgan-Hughes, N. J., Hood, G.. Anaesthesia for a patient with a cardiac transplant. Continuing Educ Anaesth Crit Care Pain 2002; 2(3): 74–8.CrossRefGoogle Scholar
Vaughan, E.. Williams classification of antidysrhythmic drugs. Pharmacol Ther B 1975; 1: 115–38.Google Scholar
Singh, B.. Beta-blockers and calcium channel blockers as anti-arrhythmic drugs. In: Zipes, D., Jalife, J.. Cardiac Electrophysiology from Cell to Bedside. Philadelphia: Saunders, 2004; 918–31.Google Scholar

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