The chapter first presents a general approach to HCI research. The general approach comprises addressing the topic or problem of designing human–computer interactions, performing of actions to progress that approach to designing human–computer interactions, evaluating of the success of the actions performed to progress that approach to designing human–computer interactions and cumulating of the successes as a way of establishing whether the topic or problem of designing human–computer interactions has been addressed or not. The chapter then proposes a General Framework for HCI research (including a core framework) comprising discipline, general as common, general problem, particular scope, general research, general knowledge and general practices. The General Framework is followed by a general design research exemplar as general design research cycles. The lower-level general framework comprises application, interactive system and performance.