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Chapter 13 - Animal Models in Anxiety Research

Published online by Cambridge University Press:  08 March 2021

By
Madhusoothanan Bhagavathi Perumal  and
Pankaj Sah
Edited by
Gerard J. Byrne  and
Nancy A. Pachana
Gerard J. Byrne
Affiliation:
University of Queensland
Nancy A. Pachana
Affiliation:
University of Queensland
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Summary

Fear and anxious apprehension are highly evolutionarily conserved responses triggered by a real or perceived imminent threat. These are adaptive responses, classically described as fight or flight responses, which comprise emotional, autonomic, and motor arousal. They are rapidly initiated and diminish as the danger abates. Anxiety states display physiological features that are similar to those evoked by fear, but as defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM) of the American Psychiatric Association, these behavioural disturbances persist beyond the appropriate period. Anxiety disorders are prevalent in all societies, and in 2014 they were the sixth leading cause of disability worldwide in terms of years lived with disability.

Type
Chapter
Information
Anxiety in Older People
Clinical and Research Perspectives
 , pp. 205 - 225
Publisher: Cambridge University Press
Print publication year: 2021

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