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Application of an antibiotic spectrum index in the neonatal intensive care unit

Published online by Cambridge University Press:  29 July 2019

Alexandra C. Lahart*
Affiliation:
Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri
Christopher C. McPherson
Affiliation:
Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri
Jeffrey S. Gerber
Affiliation:
Division of Infectious Diseases and The Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
Barbara B. Warner
Affiliation:
Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri
Brian R. Lee
Affiliation:
Health Services and Outcomes Research, Children’s Mercy Hospital, Kansas City, Missouri
Jason G. Newland
Affiliation:
Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri
*
Author for correspondence: Alexandra C. Lahart, Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, 1 Children’s Place, St Louis, MO 63110. Email: alahart@wustl.edu

Abstract

Antimicrobial stewardship programs typically use days of therapy to assess antimicrobial use. However, this metric does not account for the antimicrobial spectrum of activity. We applied an antibiotic spectrum index to a population of very-low-birth-weight infants to assess its utility to evaluate the impact of antimicrobial stewardship interventions.

Type
Concise Communication
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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References

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