Impaired recall for early items (primacy) and late items (recency) on
word list recall tests are seen in Alzheimer's disease (AD). We
compared conventional scoring on the Telephone Instrument for Cognitive
Status (TICS) recall list with scorings based on retention-weighted recall
(RWR: each item weighted by its serial position) in older adults
participating in a community-based aging study. Subjects with mild AD
(N = 18) did not differ from those without dementia (N =
231) with respect to recency (46% vs. 59%, p = 0.2), but
had impaired primacy (2% vs. 39%, p < .001) on word
recall on the TICS. RWR scoring improved the effect size (1.52
SD) compared to conventional scoring (1.08 SD). With a
fixed sensitivity of 85%, specificity was lower using conventional scoring
(56%) than RWR (76%) scoring. Our findings suggest that optimized RWR
scoring of word list free recall can improve detection of mild AD compared
to conventional scoring. (JINS, 2006, 12,
436–440.)