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4 results

  • Chapter 8 - Neonatal Seizures Due to Acute Causes
  • from Part II - Practice of Neuromonitoring: Neonatal Intensive Care Unit
  • Edited by Cecil D. Hahn, Courtney J. Wusthoff
  • Book: Neuromonitoring in Neonatal and Pediatric Critical Care
  • Published online: 08 September 2022
  • Print publication: 15 September 2022, pp 116-125
  • View extract

    Summary

    In the neonatal period, the majority of seizures are acute reactive events provoked by injury. Some etiologies require immediate diagnosis and treatment. Many of these acute, symptomatic seizures resolve once the underlying etiology is corrected or the acute neurological disruption of the causal event subsides. The electroencephalogram (EEG), amplitude-integrated EEG (aEEG), or quantitative electroencephalography (QEEG) may aid in rapid diagnosis and treatment of clinical and subclinical seizures. The new ILAE classification for neonatal seizures emphasizes the need for EEG for accurate diagnosis. Most EEG patterns in the neonate are non-specific to the etiology of seizures. However, even while non-specific, certain patterns can help direct the diagnostic evaluation. In many cases neuromonitoring may have specific characteristics that are helpful to direct further workup. This chapter discusses neuromonitoring in neonatal seizures due to acute causes, including vascular injury (stroke or hemorrhage), infection, acute metabolic disturbance, brain injury of prematurity, and neonatal abstinence syndrome.