This paper examines how state and non-state actors govern through pursuing speculative conservation among resource-dependent people who must renegotiate altered livelihoods amidst extractivism in ruptured landscapes. As donor aid declines and changes form, bilaterals, state agencies, and civil society now pursue advocacy in overlapping spaces of intensifying extractivism and speculative governance in the ruptured frontiers of Southeast Asia. In these spaces, bilaterals and non-governmental organisations (NGOs) struggle to work with upland farmers who negotiate the contrasting expectations of the abstract, speculative nature of conservation initiatives and the lucrative nature of extractive labour in the face of dramatic transformations of agrarian livelihoods and landscapes. Through a case study of the Philippine uplands, we demonstrate that as speculative conservation unfolds and manifests within and beyond these landscapes, it endeavours to revalue nature monetarily in ways that help reorganise labour and capital in an effort to overcome the exhaustion of capital wrought by rupture. We propose that during moments of rupture speculative conservation coproduces value from ruin by renewing and preserving capital flows.

We question whether the increasingly popular, radical idea of turning half the Earth into a network of protected areas is either feasible or just. We argue that this Half-Earth plan would have widespread negative consequences for human populations and would not meet its conservation objectives. It offers no agenda for managing biodiversity within a human half of Earth. We call instead for alternative radical action that is both more effective and more equitable, focused directly on the main drivers of biodiversity loss by shifting the global economy from its current foundation in growth while simultaneously redressing inequality.

Subcortical hyperintensities (SH) on neuroimaging are a prominent feature of vascular dementia (VaD) and SH severity correlates with cognitive impairment in this population. Previous studies demonstrated that SH burden accounts for a degree of the cognitive burden among VaD patients, although it remains unclear if individual factors such as cognitive reserve influence cognitive status in VaD. To address this issue, we examined 36 individuals diagnosed with probable VaD (age = 77.56; education = 12). All individuals underwent MMSE evaluations and MRI brain scans. We predicted that individuals with higher educational attainment would exhibit less cognitive difficulty despite similar levels of SH volume, compared to individuals with less educational attainment. A regression analysis revealed that greater SH volume was associated with lower scores on the MMSE. Additionally, education moderated the relationship between SH volume and MMSE score, demonstrating that individuals with higher education had higher scores on the MMSE despite similar degrees of SH burden. These results suggest that educational attainment buffers the deleterious effects of SH burden on cognitive status among VaD patients. (JINS, 2011, 17, 531–536)

The science of extra-solar planets is one of the most rapidly changing areas of astrophysics and since 1995 the number of planets known has increased by almost two orders of magnitude. A combination of ground-based surveys and dedicated space missions has resulted in 560-plus planets being detected, and over 1200 that await confirmation. NASA's Kepler mission has opened up the possibility of discovering Earth-like planets in the habitable zone around some of the 100,000 stars it is surveying during its 3 to 4-year lifetime. The new ESA's Gaia mission is expected to discover thousands of new planets around stars within 200 parsecs of the Sun. The key challenge now is moving on from discovery, important though that remains, to characterisation: what are these planets actually like, and why are they as they are?

In the past ten years, we have learned how to obtain the first spectra of exoplanets using transit transmission and emission spectroscopy. With the high stability of Spitzer, Hubble, and large ground-based telescopes the spectra of bright close-in massive planets can be obtained and species like water vapour, methane, carbon monoxide and dioxide have been detected. With transit science came the first tangible remote sensing of these planetary bodies and so one can start to extrapolate from what has been learnt from Solar System probes to what one might plan to learn about their faraway siblings. As we learn more about the atmospheres, surfaces and near-surfaces of these remote bodies, we will begin to build up a clearer picture of their construction, history and suitability for life.

The Exoplanet Characterisation Observatory, EChO, will be the first dedicated mission to investigate the physics and chemistry of Exoplanetary Atmospheres. By characterising spectroscopically more bodies in different environments we will take detailed planetology out of the Solar System and into the Galaxy as a whole.

EChO has now been selected by the European Space Agency to be assessed as one of four M3 mission candidates.

Background: It is well known that the global population is aging and that those over the age of 80 are the fastest growing part of this expansion. Also known is that prevalence of hypertension and cognitive decline both increase with increasing age.

Method: The Hypertension in the Very Elderly Trial (HYVET) was a double blind placebo-controlled trial of antihypertensive treatment (indapamide SR 1.5 mg ± perindopril 2–4 mg) and recruited only those hypertensives who were aged 80 or over and were without a diagnosis of dementia at baseline. Systolic blood pressure had to be in the range 160–199 mmHg and diastolic pressure <110 mmHg. Cognitive function was assessed at baseline using the Mini-mental State Examination prior to randomization into the trial. Also collected at baseline was information relating to sociodemographic, clinical, cardiovascular and biochemical factors which may impact upon cognitive function. This paper reports on the baseline cognitive function data from the HYVET trial and its relationship to these factors.

Results: The mean age of the 3763 HYVET participants who had full cognitive function data at baseline was 83.6 years; 60 percent were female. The median MMSE score at baseline was 26 and, in multivariate analyses, higher at younger age, with male gender, higher educational level, having higher creatinine, higher total cholesterol and lower high-density lipoprotein cholesterol.

Conclusions: This is the first such study to examine a large number of very elderly hypertensives and it shows some similar patterns to those seen in younger elderly groups.

Large food portions may be facilitating excess energy intake (EI) and adiposity among adults. The present study aimed to assess the extent to which EI and amounts of foods consumed are influenced by the availability of different-sized food portions. A randomised within-subject cross-over, fully residential design was used, where forty-three (twenty-one men and twenty-two women) normal-weight and overweight adults were randomly allocated to two separate 4 d periods where they were presented with either ‘standard’ or ‘large’ food portions of the same foods and beverages. The main outcome measures were the amount of food (g) and EI (MJ) consumed throughout each study period. Mean EI over 4 d was significantly higher on the large portion condition compared with the standard condition in the total group (59·1 (sd 6·6) v. 52·2 (sd 14·3) MJ; P = 0·020); men and women increased their EI by 17 % (10 (sd 6·5) MJ; P < 0·001) and 10 % (4 (sd 6·5) MJ; P = 0·005) respectively when served the large food portions relative to the standard food portions. The increased intakes were sustained over the 4 d in the large portion condition with little evidence of down-regulation of EI and food intake being made by subjects. Increased food portion size resulted in significant and sustained increases in EI in men and women over 4 d under fully residential conditions. The availability and consumption of larger portions of food may be a significant factor contributing to excess EI and adiposity.

This study evaluates the influence of man-made activities on the benthic environment at two different marinas: Southsea Marina on the south coast of England, and Minimes Marina on the Atlantic coast of France. We assessed the differences in: (1) sediment percentage organic matter, particle size and heavy metal concentration, using copper (Cu), cadmium (Cd), zinc (Zn) and lead (Pb) as contamination indicators; (2) sediment elutriate toxicity (LC50) using algal (Fucus serratus) bioassay; and (3) benthic community characteristics (number of species, abundance, most contributing species (SIMPER) and biotic index (AMBI)). Canonical correspondence analysis (CCA) was performed to relate the abundance of species to the environmental variables. At both marinas, we observed an increasing gradient of contamination from outside to the innermost sites. At both marinas, the lowest macrofaunal abundance was recorded at the innermost sites and differences in benthic community structure were observed between sites. At Southsea Marina, the cirratulids Tharyx marioni and T. killariensis and the cossurid Cossura pygodactylata dominated sites outside, while the opportunistic species Capitellides girardi dominated the innermost sites. At Minimes Marina, the cirratulid Streblospio shrubsolii was abundant outside and at the middle sites but was almost absent at the innermost sites. The biotic index—AMBI—indicated that sediments in the innermost sites were heavily disturbed at Southsea Marina and slightly to moderately disturbed at Minimes Marina. In Southsea, the AMBI was positively correlated to the sediment metal concentrations (Cu, Zn and Cd) and elutriate toxicity (LC50), while in Minimes the AMBI was positively correlated to the % of sediment fine particle and elutriate toxicity (LC50).

The objective of the present study was to examine the associations between the portion sizes of food groups consumed with measures of adiposity using data from the National Diet and Nutrition Survey of British adults. Seven-day weighed dietary records, physical activity diaries and anthropometric measurements were used. Foods eaten were assigned to thirty different food groups and analyses were undertaken separately for men and women. The median daily portion size of each food group consumed was calculated. The potential misreporting of dietary energy intake (EI) was identified using the following equation: EI − estimated energy requirements × 100 = percentage of under-reporting (UR) of energy needs. Multinomial logistic regression (adjusted for age, social class, physical activity level and UR) was used to determine the portion sizes of food groups most strongly associated with obesity status. Few positive associations between the portion sizes of food groups consumed and obesity status were found. However, UR was prevalent, with a median UR of predicted energy needs of 34 and 33 % in men and women, respectively. After the adjustment was made for UR, more associations between the food groups and obesity status became apparent in both sexes. The present study suggests that the true effect of increased portion size of foods on obesity status may be masked by high levels of UR. Alternatively, these data may indicate that an increased risk of obesity is not associated with specific foods/food groups but rather with an overall increase in the range of foods and food groups being consumed.

IN AN ESSAY SHE ORIGINALLY published in the Examiner and later reissued in the collection A Housewife's Opinions, the Victorian feminist poet Augusta Webster imaginatively fuses two female figures: the medieval cloistered saint and the saintly, cloistered wife of her own age. Her “Saint Opportune” is a parody, the life of a most “unobtrusive saint,” whose name (taken from a street in Poitiers) is “the epitome of her virtues, her charter of beatification” (“Opportune” 203). “In all things always acceptable,” Saint Opportune “was, of course, not a martyr,” because “in her day anybody could have been that, and her grace was an exceptional one” (203–04). Rather, she led “an existence of honourable safety” (204), being a child so trouble-free that her clothes always fitted just right, and “she neither lagged behind her teachers' hopes nor prematurely outshot their skill” (206), “a girl about whom it was remarkable that she never was remarked” (208), eventually becoming medieval version of the Victorian domestic saint: St. Opportune's career as a wife was the perfect accomplishment of the highest auguries of her youth. No matter at what moment of unpunctuality her husband came in bent upon his dinner, whether a quarter of an hour before time or three-quarters of an hour behind, the soup was steaming ready in the tureen, the boiled fish firm and flaky or the fried fish at the evanescent perfect phase of crispness, the joint done to a turn as he liked it, the entrees at their harmonious prime, nothing soddened, nothing hurried, all ready and right with no too much and no too little, according to the variable standard of the tastes of the master of the house. (210) Capping her career of “inspired unobtrusiveness” (208), Saint Opportune withdraws to a convent when her first wrinkle appears (so her husband can be remarried to “a damsel of pleasing aspect who reminded him of her in her fairer days” [211]), only to die soon afterwards so as to oblige her order: She did not live long in the cloister. A neighbouring convent lost a nun of great sanctity, who on her burial began working miracles. St. Opportune's convent, till then the leading one in those parts, was much mortified but saw no remedy. St. Opportune at once died and instantly worked a miracle. What that miracle was this investigator has failed to discover; but it restored the convent to its former supremacy and proved to all after ages the right of St. Opportune to beatification. (212)

This essay argues that Thackeray's unillustrated three-volume novel The History of Henry Esmond is shaped by modes of perception and representation nascent in the visual culture of nineteenth-century England and epitomized in the comic strip. Through one of Thackeray's own picture stories, it first describes the ekphrastic basis of his narrative imagination and then contextualizes his visual thinking by relating his journalistic reflections on images in society to recent cultural histories of visual experience. Subsequently, the essay demonstrates that Henry Esmond, a seemingly monumental historical novel, is structured by the fractured syntax of the comic picture story and that the picture story's revisionist impulse decenters the autobiographical subject, Henry Esmond, and highlights the heuristic function of his narrative. The argument concludes by revisiting Thackeray's meditations on the picture story, the railroad, and modernity, suggesting that his texts—both picture stories and this bildungsroman—foreground a transformative vision and thus reveal the contingency of subjectivity.