IAU Symposium 336, Astrophysical Masers: Unlocking the Mysteries of the Universe, took place between 4 - 8 September, 2017 in Cagliari, on the beautiful island of Sardinia. The Symposium, the fifth focusing on masers as a tool for astrophysics, was dedicated to our friend and colleague Malcolm Walmsley, who sadly passed away shortly before the meeting. To quote Karl Menten: “Malcolm made numerous fundamental contributions to our understanding of the physics and chemistry of star formation and the interstellar medium. He was an exceptional scientist, a highly esteemed colleague and a true gentleman”. Vale Malcolm. The topics discussed at the symposium covered a huge range, from star-formation, evolved stars, galaxies and their constituents, super-massive black-holes to cosmology.