The main purpose of this paper is, first, to consider the nature of psychopathic personality disorder, and then, to consider the capacity for criminal culpability of psychopaths and whether it is justified to hold them culpable. Initially, a description of the disorder of psychopathy shall be presented, highlighting those character traits deemed relevant for findings of criminal culpability. There follows a brief discussion of the main theories justifying punishment and their position on punishing persons incapable of effective participation in moral reasoning. Lastly, a discussion of the importance for moral condemnation of the capacity to feel empathy and the absence of that capacity in the psychopath, leading to the conclusion that these persons should not be regarded as blameworthy.