The yield stress properties and the associated slip systems of stoichiometric NiAl single crystals were investigated in terms of crystal orientation, temperature and the deformation mode. The CRSS was, in a wide range of experimental conditions, higher in the sequence of {110}<100>, {100}<100> and {hk0}<100> slips. In all the crystal orientations studied, the CRSS in compression was higher than the CRSS in tension particularly at low temperatures. The tension-compression asymmetry on the CRSS was understood qualitatively as being due to the effect of the normal stress on the core structure of a <001> dislocation.