At doses of 75 mg./kg. given per os, Neguvon was ineffective against Sarcoples scabiei var. Auchenidae. Benzene hexachloride (BHC) per os was ineffective at doses of 20 mg./kg. and killed alpacas when the dose was increased. Spraying the lesions with BHC killed the acari and lesions quickly disappeared. Psoroptes communis, the cause of otitis in alpacas, was equally susceptible to spraying. Lesions and their location are described and attention is drawn to the possible role of acari in nostrils and perinea in the epidemiology of the disease. Dipping is, at present, the only method of cure worth using, but the search for systemic acaricides should be continued.