Recent clinical trials have successfully slowed Alzheimer's disease dementia progression, but only in early-stage patients. Society must therefore shift to early diagnosis. By framing this is as an engineering design challenge, we argue that a systems approach will identify solutions by providing the means to validate dementia medical technologies from multiple levels and perspectives: society, government, public health, healthcare, and patient ecosystems. We show that new data-enabled design methods can facilitate these different granularities of thinking and outline the need for designers.