“Medical science,” says Dr. Donkin, “is indebted to Professor Simpson for having first directed attention to the coexistence of albuminuria and puerperal mania, in a contribution to the Obstetric Society of Edinburgh, in 1856. In this paper Dr. Simpson contented himself with demonstrating merely the frequent coexistence of the two morbid conditions, without attempting to explain the exact pathological relation between the renal and mental affections, leaving that to be accomplished by future clinical investigation. Dr. Simpson's communication is, I believe, up to the present time, the only contribution we possess on the subject, either in our own or any other language.”