Book contents
- Non-Motor Parkinson’s Disease
- Non-Motor Parkinson’s Disease
- Copyright page
- Contents
- Contributors
- Introduction
- Chapter 1 Parkinson’s Disease: An Overview of the Non-Motor Symptomatology
- Chapter 2 Evaluation of the Patient with Parkinson’s Disease in the Early Stages: Non-Motor Phase
- Chapter 3 Non-Motor Symptoms in Late-Stage Parkinson’s Disease
- Chapter 4 Neuropathology of Non-Motor Parkinson’s Disease Symptoms
- Chapter 5 Neuroimaging Studies in Non-Motor Parkinson’s Disease Symptoms
- Chapter 6 Mild Cognitive Impairment
- Chapter 7 Cognitive Dysfunction in Parkinson’s Disease
- Chapter 8 Neuropsychiatric (Behavioral) Symptoms in Parkinson’s Disease
- Chapter 9 Mood Disorders in Parkinson’s Disease
- Chapter 10 Olfactory Dysfunction in Parkinson’s Disease and Related Disorders
- Chapter 11 Oculomotor and Visual-Vestibular Disturbances in Parkinson’s Disease
- Chapter 12 Autonomic Dysfunction and Failure in Parkinson’s Disease
- Chapter 13 Gastrointestinal Disturbances in Parkinson’s Disease Including the Management of Sialorrhea
- Chapter 14 Sexual Dysfunction in Parkinson’s Disease
- Chapter 15 Sleep Disturbances in Parkinson’s Disease
- Chapter 16 Musculoskeletal Disorders and Pain in Parkinson’s Disease
- Chapter 17 Cutaneous Manifestations of Parkinson’s Disease
- Chapter 18 Genetics of Non-Motor Symptoms of Parkinson’s Disease
- Chapter 19 Drug-Induced Non-Motor Symptoms in Parkinson’s Disease
- Chapter 20 Impulse Control Disorders and the Dopamine Dysregulation Syndrome
- Chapter 21 Serotonin Syndrome and Drug Interactions, Hypertensive Complications, and, Adverse Effects of Monoamine Oxidase Inhibitors in Patients with Parkinson’s Disease
- Chapter 22 Parkinson’s Disease and Pregnancy
- Index
- Plate Section (PDF Only)
- References
Chapter 3 - Non-Motor Symptoms in Late-Stage Parkinson’s Disease
Published online by Cambridge University Press: 05 March 2022
- Non-Motor Parkinson’s Disease
- Non-Motor Parkinson’s Disease
- Copyright page
- Contents
- Contributors
- Introduction
- Chapter 1 Parkinson’s Disease: An Overview of the Non-Motor Symptomatology
- Chapter 2 Evaluation of the Patient with Parkinson’s Disease in the Early Stages: Non-Motor Phase
- Chapter 3 Non-Motor Symptoms in Late-Stage Parkinson’s Disease
- Chapter 4 Neuropathology of Non-Motor Parkinson’s Disease Symptoms
- Chapter 5 Neuroimaging Studies in Non-Motor Parkinson’s Disease Symptoms
- Chapter 6 Mild Cognitive Impairment
- Chapter 7 Cognitive Dysfunction in Parkinson’s Disease
- Chapter 8 Neuropsychiatric (Behavioral) Symptoms in Parkinson’s Disease
- Chapter 9 Mood Disorders in Parkinson’s Disease
- Chapter 10 Olfactory Dysfunction in Parkinson’s Disease and Related Disorders
- Chapter 11 Oculomotor and Visual-Vestibular Disturbances in Parkinson’s Disease
- Chapter 12 Autonomic Dysfunction and Failure in Parkinson’s Disease
- Chapter 13 Gastrointestinal Disturbances in Parkinson’s Disease Including the Management of Sialorrhea
- Chapter 14 Sexual Dysfunction in Parkinson’s Disease
- Chapter 15 Sleep Disturbances in Parkinson’s Disease
- Chapter 16 Musculoskeletal Disorders and Pain in Parkinson’s Disease
- Chapter 17 Cutaneous Manifestations of Parkinson’s Disease
- Chapter 18 Genetics of Non-Motor Symptoms of Parkinson’s Disease
- Chapter 19 Drug-Induced Non-Motor Symptoms in Parkinson’s Disease
- Chapter 20 Impulse Control Disorders and the Dopamine Dysregulation Syndrome
- Chapter 21 Serotonin Syndrome and Drug Interactions, Hypertensive Complications, and, Adverse Effects of Monoamine Oxidase Inhibitors in Patients with Parkinson’s Disease
- Chapter 22 Parkinson’s Disease and Pregnancy
- Index
- Plate Section (PDF Only)
- References
Summary
Late-stage Parkinson’s disease (PD) poses a significant challenge to clinicians. In addition to this, there is a lack of clarity in even its terminology and definition. It has been termed as advanced, late-stage, end-stage, and even palliative PD [1–3]. As the term late-stage PD has become the most widespread, it will be used henceforth. The criteria for diagnosing late-stage PD too has varied, with initial literature using varying cut-offs of the Hoehn and Yahr (H&Y) staging to determine the degree of advancement [1–3]. There has been significant criticism to this approach; it was asserted that while H & Y is heavily weighted towards postural instability and lower limb problems, it may overlook other motor symptoms that contribute to the advancing state, and it excludes non-motor symptoms (NMS). It was also written with the assumption that severity of PD is most related to motor symptoms [4].
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- Non-motor Parkinson's Disease , pp. 27 - 34Publisher: Cambridge University PressPrint publication year: 2022