Growth chamber and field studies were conducted to investigate the possibility of an interaction between the herbicides 4-(methylsulfonyl)-2,6-dinitro-N,N-dipropylaniline (nitralin), a,a,a-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine (trifluralin), 3- (m-tri-fluromethylphenyl)-1,1-dimethylurea (fluometuron), and 2,4-bis(isopropylamino)-6-methylmercapto-s-triazine (prometryne), and the seedling disease organism Rhizoctonia solani Kuehn in cotton (Gossypium hirsutum L.). When high levels of trifluralin or prometryne were used in the growth chamber, an interaction with the pathogen that was injurious to the cotton occurred. Prometryne and fluometuron produced an antagonistic effect on R. solani.
Under field conditions, R. solani usually caused cotton injury. Interactions injurious to the cotton occurred between trifluralin and a low level of R. solani and between nitralin and a high level R. solani infestation. No interactions occurred with fluometuron or prometryne. In all instances, the effect occurred only when the herbicides were being used at high rates.