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Topography of long- and middle-wavelength sensitive cone opsin gene expression in human and Old World monkey retina



The topographical distributions of the relative ratio of long- (L) and middle- (M) wavelength sensitive cone opsin messenger RNA (mRNA) in human and baboon retinas were mapped using real-time polymerase chain reaction. The L:M mRNA ratio increased in a central-to-peripheral gradient in both species, being quite pronounced for humans.


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Address correspondence and reprint requests to: Maureen Neitz, Department of Ophthalmology, The Eye Institute, 925 North 87th Street, Milwaukee, WI 53226. E-mail:


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Topography of long- and middle-wavelength sensitive cone opsin gene expression in human and Old World monkey retina



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