Hostname: page-component-77c89778f8-cnmwb Total loading time: 0 Render date: 2024-07-18T18:16:32.074Z Has data issue: false hasContentIssue false

Energy deposition in selected-mammalian cell for several-MeV single-proton beam

Published online by Cambridge University Press:  28 March 2007

K. Ding*
Affiliation:
Institute of Biological Science and Technology, Beijing Jiaotong University, Beijing, P.R. China 100044
Z. Yu
Affiliation:
The Key Laboratory of Ion-Beam Bioengineering, Chinese Academy of Science, Hefei, P.R. China 230031
Get access

Abstract

The phenomena resulting from interaction between ion beam and mammalian cell pose important problems for biological applications. Classic Bethe-Bloch theory utilizing attached V79 mammalian cell has been conducted in order to establish the stopping powers of the mammalian cell for several-MeV single-proton microbeam. Based on the biological structure of the mammalian cell, a physical model is proposed which presumes that the attached cell is simple MWM model. According to this model and Monte Carlo simulation, we studied the energy deposition and its ratio on the selected attached mammalian cell for MeV proton implantation.

Keywords

Type
Research Article
Copyright
© EDP Sciences, 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Z.L. Yu, Introduction to Ion Beam Biotechnology (Springer, New York, 2005)
Yu, Z.L., Yang, J., Wu, Y., Cheng, B., He, J., Huo, Y., Nucl. Instr. Meth. B 80–81, 1328 (1993)
Anuntalabhochai, S., Chandej, R., Phanchaisri, B., Yu, L.D., Vilaithong, T., Brown, I.G., Appl. Phys. Lett. 78, 2393 (2001) CrossRef
Vilaithong, T., Yu, L.D., Alisi, C., Phanchaisri, B., Apavatjrut, P., Anuntalabhochai, S., Surf. Coat. Technol. 128–129, 133 (2000) CrossRef
Yu, L.D., Vilaithong, T., Phanchaisri, B., Apavatjrut, P., Anuntalabhochai, S., Evans, P., Brown, I.G., Nucl. Instr. Meth. B 206, 586 (2003) CrossRef
Ding, K.J., Xu, M.L., Wu, L.J., Yu, Z.L., Plasma Sci. Technol. 8, 363 (2006)
Hill, C.K., Nelms, B.E., MacKay, J.F., Pearson, D.W., Kennan, W.S., Mackie, T.R., DeLuca Jr, P.M.., M.J. Lindstrom, M.N. Gould, Radiat. Res. 150, 513 (1998) CrossRef
Gould, K.M., Townsend, S., Stretch, A., Stevens, D.L., Goodhead, D.T., Int. J. Radiat. Biol. 58, 499 (1990)
Goodhead, D.T., Thacker, J., Int. J. Radiat. Biol. 31, 541 (1977)
Raju, M.R., Carpents, S.G., Chmielewski, J.J., Schillaci, M.E., Wilder, M.E., Freyer, J.P., Johnson, N.F., Schor, P.L., Sebring, R.J., Goodhead, D.T., Radiat. Res. 110, 396 (1987) CrossRef
Schillaci, M.E., Carpenter, S., Raju, M.R., Schring, R.J., Wilder, M.E., Goodhead, D.T., Radiat. Res. 118, 83 (1989) CrossRef
Brenner, D.J., Bird, R.P., Zaider, M., Goldhagen, P., Kliauga, P.J., Rossi, H.H., Res. 110, 413 (1987)
Bettega, D., Calzolari, P., Doglia, S.M., Dulio, B., Tallone, L., Villa, A.M., Int. J. Radiat. Biol. 74, 397 (1998) CrossRef
Goodhead, D.T., Thacker, J., Cox, R., Int. J. Radiat. Biol. 36, 101 (1979)
Hill, M.A., Vecchia, M.D.T., Townsend, K.M.S., Goodhead, D.T., Phys. Med. Biol. 43, 467 (1997)
Ding, K.J., Wu, L.J., Wu, Y.J., Yu, Z.L., Plasma Sci. Technol. 8, 751 (2006)
Hu, Z.W., Ding, K.J., Yu, L.D., Zhang, J., Wu, L.J., Yu, Z.L., Chin. Phys. 15, 0659 (2006)
J.F. Ziegler, J.P. Biersack, U. Littmark, The Stopping and Range of Ions in Solids (Pergamon, New York, 1985)
Bethe, H., Ann. Physik 5, 325 (1930) CrossRef
Bethe, H., Z. Phys. 76, 293 (1932) CrossRef
Bloch, F., Ann. Phys. 16, 285 (1933) CrossRef
Bloch, F., Z. Phys. 81, 363 (1933) CrossRef
W.H. Barkas, M.J. Berger, No. 1133 (Washington, DC, NAS-NRC, 1967)
Porter, L.E., Lin, H., J. Appl. Phys. 67, 6613 (1990) CrossRef
Ashley, J.C., Ritchie, R.H., Brandt, W., Phys. Rev. A 8, 2402 (1973) CrossRef
Ashley, J.C., Ritchie, R.H., Brandt, W., Phys. Rev. B 5, 2393 (1972) CrossRef
Ritchie, R.H., Brandt, W., Phys. Rev. A 17, 2102 (1978) CrossRef
Ashley, J.C., Phys. Rev. B 9, 334 (1974) CrossRef
A.L. Lehninger, Biochemistry, 2nd edn. (Worth Publishers Inc., 1975)
Cannell, R.J., Watt, D.E., Phys. Med. Biol. 30, 255 (1985) CrossRef
Boudaïffa, B., Cloutier, P., Hunting, D., Huels, M.A., Sanche, L., Science 287, 1658 (2000)
Brenner, D.J., Ward, J.F., Int. J. Radiat. Biol. 61, 737 (1992) CrossRef