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Analysis of pulsed photoacoustic signal: theoretical study of the diffusion of chromophores in the human skin

Published online by Cambridge University Press:  28 June 2002

N. Benamar*
Affiliation:
Faculté des Sciences de Meknès, Département de Physique, BP 4010 Beni M'hamed, Meknès, Morocco
F. Lahjomri
Affiliation:
École Nationale des Sciences Appliquées de Tanger, Université Abdelmalek Essaadi, BP 416, Tanger principal, Tanger, Morocco
E. Chatri
Affiliation:
Faculté des Sciences de Meknès, Département de Physique, BP 4010 Beni M'hamed, Meknès, Morocco
E. M. Achour
Affiliation:
Faculté des Sciences de Kénitra, Université Ibn Tofail, Faculté des Sciences, BP 133, 14000 Kénitra, Morocco
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Abstract

Pulsed photoacoustic spectroscopy (PPAS) provides a convenient means for in vivo and in situ monitoring of human skin properties and surface concentrations of locally applied substances, such as drugs and cosmetics. In this article, we applied the one-dimensional theoretical model of Mandelis and Royce (J. Appl. Phys. 50, 6 (1979)) to simulate the photoacoustic response of human skin and diffusion phenomena through it, for various optical absorption coefficients and sample thicknesses. This approach is analyzed through the temperature and pressure variations in the photoacoustic cell.

Keywords

Type
Research Article
Copyright
© EDP Sciences, 2002

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