We present observations of the binary Sirius A / Sirius B performed with HST-GHRS. Two interstellar clouds are detected on this sightline, one of them being identified as the Local Interstellar Cloud (LIC). Lyman α interstellar lines are also observed, but whereas the deuterium Lyman α line is well detected in the LIC with an abundance in agreement with that obtained by Linsky et al. (1995), no significant D i line is detected in the second cloud. The deuterium abundance which we measured in this cloud is 0 < (D/H)ism < 1-6 × 10−5. Despite the large error bar, this sightline appears consequently as a good candidate for a low (D/H)ism.