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  • Simon Fishel (a1), Judy Timson (a1), Steven Green (a1), Jenny Hall (a1), Ken Dowell (a1) and Lucas Klentzeris (a1)...


Micromanipulation technology entered the forum of human conception in vitro in the late 1980s. It was erroneously perceived as a new technology – a purely mechanical approach to bypass failures of conception in vitro, the aetiology of which were unknown. In fact, it is the modification of technology developed since the beginning of this century, and its logical utilization for conception in vitro, preconception (polar body) biopsy and preimplantation (blastomere and trophectoderm) biopsy in the realm of human infertility and genetic disorders.


Corresponding author

Simon Fishel, NURTURE (Nottingham University Research & Treatment Unit in Reproduction), Department of Obstetrics & Gynaecology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH, UK.


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