Hostname: page-component-77c89778f8-m42fx Total loading time: 0 Render date: 2024-07-24T06:36:04.989Z Has data issue: false hasContentIssue false
  • English
  • Français

Thirty-five males with double Y chromosome

Published online by Cambridge University Press:  09 July 2009

J. Nielsen  and
A.-L. Christensen
J. Nielsen*
Affiliation:
Cytogenetic Laboratory and the Department of Clinical Psychology, Århus State Hospital, Risskov, Denmark
A.-L. Christensen
Affiliation:
Cytogenetic Laboratory and the Department of Clinical Psychology, Århus State Hospital, Risskov, Denmark
*
1Address for correspondance: Cytogenetic Laboratory at above address.
Get access Rights & Permissions [Opens in a new window]

Synopsis

Thirty-five males with double Y chromosome were studied. Among the features observed in certain subgroups of these 35 were a more than average height, minor vertebral abnormalities, abnormal seminiferous epithelium, minor EEG abnormalities, and a mean intelligence level significantly below the expected. Fifteen of the 35 were found in institutions for criminals. The frequency of XYY males among 1,500 criminal males was 8·67 per 1,000 compared with 1·24 per 1,000 among 6,455 randomly selected males in the general population. Males with double Y chromosome tended to have more difficulties at school, to be more mentally immature, to be more impulsive than their siblings, and to have more difficulty in making relationships with others.

Type
Research Article
Information
Psychological Medicine , Volume 4 , Issue 1 , February 1974 , pp. 28 - 37
Copyright
Copyright © Cambridge University Press 1974

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Arthurs, R. G. S., and Cahoon, E. B. (1964). A clinical and electroencephalographic survey of psychopatic personality. American Journal of Psychiatry, 120, 875–877.Google Scholar
Brown, W. M. Court (1968). Males with an XYY sex chromosome complement. Journal of Medical Genetics, 5, 341–359.Google Scholar
Butomo, I. V., Godinova, A. M., and Ponomarenko, A. M. (1969). Features of cerebral bioelectrical activity in Klinefelter's disease. Zhurnal Nevropatologil i Psikhiatril imeni S. S. Korsakova, 69, 53–58.Google Scholar
Christensen, A.-L., and Nielsen, J. (1973). Psychological studies of ten patients with the XYY syndrome. British Journal of Psychiatry, 123, 219–221.CrossRefGoogle ScholarPubMed
Christensen, K. R., and Nielsen, J. (1974). Incidence of chromosome aberrations in a child psychiatric hospital. Clinical Genetics (In press.)CrossRefGoogle Scholar
Fenton, G. W., Tennent, T. G., Comish, K. A., and Rattray, N. (1971). The EEG and sex chromosome abnormalities. British Journal of Psychiatry, 119, 185–190.CrossRefGoogle ScholarPubMed
Fox, R. G. (1971). The XYY offender: a modern myth? The Journal of Criminal Law, Criminology and Police Science, 62, 59–73.Google Scholar
Friedrich, U., Erling, E. B., and Nielsen, J. (1971). Chromosomenuntersuchung bei rechtspsychiatrischen Patienten. Zeitschrift für Rechtsmedizin, 68, 138–148.Google Scholar
Friedrich, U., and Nielsen, J. (1973). Chromosome studies in 5,049 consecutive newborn children. Clinical Genetics, 4, 333–343.CrossRefGoogle Scholar
Gerald, P. S., and Walzer, S. (1970). Chromosome studies of normal newborn infants. In Human Population Cytogenetics, pp. 143–151. Edited by Jacobs, P. A., Price, W. H., and Law, P.. Pfizer Medical Monographs 5. University Press: Edinburgh.Google Scholar
Hamerton, J. L. (ed.) (1971). Human Cytogenetics. Vol. 2. Academic Press, New York.Google Scholar
Hamerton, J. L., Ray, M., Abbott, J., Williamson, C., and Ducasse, G. C. (1972). Chromosome studies in a neonatal population. Canadian Medical Association Journal, 106, 776–779.Google Scholar
Høncke, P., Strömgren, E., and Zahle, V. (1949). Elektrencephalographische Untersuchungen an Psychopathen. Archiv für Psychiatrie und Nervenkrankheiten, 183, 55–63.Google Scholar
Jacobs, P. A., Brunton, M., Melville, M. M., Brittain, R. P., and McClemont, W. F. (1965). Aggressive behaviour, mental sub-normality and the XYY male. Nature, 208, 1351–1352.Google Scholar
Jacobs, P. A., Price, W. H., Richmond, S., and Ratcliffe, R. A. W. (1971). Chromosome surveys in penal institutions and approved schools. Journal of Medical Genetics, 8, 49–58.CrossRefGoogle ScholarPubMed
Jacobs, P. A. (1972). Personal communication.Google Scholar
Kessler, S., and Moos, R. H. (1970). The XYY karyotype and criminality: a review. Journal of Psychiatric Research, 7, 153–170.CrossRefGoogle ScholarPubMed
Lubs, H. A., and Ruddle, F. H. (1970a). Chromosomal abnormalities in the human population: estimation of rates based on New Haven newborn study. Science, 169, 495–497.Google Scholar
Lubs, H. A., and Ruddle, F. H. (1970b). Applications of quantitative karyotypy to chromosome variation in 4400 consecutive newborns. In Human Population Cytogenetics, pp. 119–142. Edited by Jacobs, P. A., Price, W. H., and Law, P.. Pfizer Medical Monographs 5. University Press: Edinburgh.Google Scholar
Money, J. (1970). Impulse, aggression and sexuality in the XYY syndrome. St. John's Law Review, 44, 220–235.Google Scholar
Moor, L. (1967). Aberrations chromosomiques portant sur les gonosomes et comportement antisocial. Etat actuel de nos connaissances (I). Annales Internationales de Criminologie, 6, 459–478.Google Scholar
Nielsen, J. (1969). Klinefelter's syndrome and the XYY syndrome. Acta Psychiatrica Scandinavica, Suppl. 209.Google Scholar
Nielsen, J. (1970). Criminality among patients with Klinefelter's syndrome and the XYY syndrome. British Journal of Psychiatry, 117, 365–369.Google Scholar
Nielsen, J. (1971). Prevalence and a 2½ years incidence of chromosome abnormalities among all males in a forensic psychiatric clinic. British Journal of Psychiatry, 119, 503–512.Google Scholar
Nielsen, J., Christensen, A.-L., Johnsen, S. G., and Frøland, A. (1966). Psychopathology and testis histology in a patient with the XYY syndrome. Acta Medica Scandinavica, 180, 747–757.Google Scholar
Nielsen, J., Christensen, A.-L., Schultz-Larsen, J., and Yde, H. (1973). A psychiatric-psychological study of patients with the XYY syndrome found outside institutions. Acta Psychiatrica Scandinavica, 49, 159–168.Google Scholar
Nielsen, J., Friedrich, U., and Zeuthen, E. (1971). Stature and weight in boys with the XYY syndrome. Humangenetik, 14, 66–68.Google Scholar
Nielsen, J., and Henriksen, F. (1972). Incidence of chromosome aberrations among males in a Danish youth prison. Acta Psychiatrica Scandinavica, 48, 87–102.Google Scholar
Nielsen, J., Sørensen, A., Theilgård, A., Frøland, A., and Johnsen, S. G. (1969c). A psychiatric-psychological study of 50 severely hypogonadal male patients, including 34 with Klinefelter's syndrome, 47, XXY. Acta Jutlandica, 41, No. 3. Munksgård: Copenhagen.Google Scholar
Nielsen, J., Stürup, G., Tsuboi, T., and Romano, D. (1969a). Prevalence of the XYY syndrome in an institution for psychologically abnormal criminals. Acta Psychiatrica Scandinavica, 45, 383–401.Google Scholar
Nielsen, J., Tsuboi, T., Tuver, B., Jensen, J. T., and Sachs, J. (1969b). Prevalence and incidence of the XYY syndrome and Klinefelter's syndrome in an institution for criminal psychopaths. Acta Psychiatrica Scandinavica, 45, 402–424.CrossRefGoogle Scholar
Noel, B., Quack, B., Durand, Y., and Rethore, M.-O. (1969). Les hommes 47, XYY. Annales de Génétique, 12, 223–236.Google Scholar
Noel, B., Mollet, J., and Quack, B. (1973). Personal communicalion.Google Scholar
Owen, D. R. (1972). The 47, XYY male: a review. Psychological Bulletin, 78, 209–233.Google Scholar
Pitcher, D. R. (1971). The XYY syndrome. British Journal of Hospital Medicine, 5, 379–393.Google Scholar
Price, W. H., and Jacobs, P. A. (1970). The 47, XYY male with special reference to behavior. Seminars in Psychiatry, 2, 30–39.Google Scholar
Raffaelli, M. (1972). Approche psychiatrique de hommes porteurs d'une dysgonosomie du type XYY. Memoire présenté á la Faculté Mixte de Médecine et de Pharmacie de Grenoble pour obtenir le Diplôme de Psychiatrie.Google Scholar
Rapaport, D., Gill, M. M., and Schafer, R. (1968). Diagnostic Psychological Testing. 2nd edn.International Universities Press: New York.Google Scholar
Ratcliffe, S. G., Stewart, A. L., Melville, M. M., Jacobs, P. A., and Keay, A. J. (1970). Chromosome studies on 3,500 newborn male infants. Lancet, 1, 121–122.Google Scholar
Sergovich, F., Valentine, G. H., Chen, A. T. L., Kinch, R. A. H., and Smout, M. S. (1969). Chromosome aberrations in 2159 consecutive newborn babies. New England Journal of Medicine, 280, 851–855.Google Scholar
Shapiro, L. R. (1970). Hormones and the XYY male. Lancet, 1, 1347.CrossRefGoogle Scholar
Skakkebaek, N. E., Philip, J., Mikkelsen, M., Hammen, R., Nielsen, J., Perbøll, O., and Yde, H. (1970). Studies on spermatogenesis, meiotic chromosomes, and sperm morphology in two males with a 47.XYY chromosome complement. Fertility and Sterility, 21, 645–656.Google Scholar
Skakkebaek, N. E., Hulten, M., Jacobsen, P., and Mikkelsen, M. (1973a). Quantification of human seminiferous epithelium. II. Histological studies in eight 47, XYY men. Journal of Reproduction and Fertility, 32, 391–401.Google Scholar
Skakkebaek, N. E., Zeuthen, E., Nielsen, J., and Yde, H. (1973b). Abnormal spermatogenesis in XYY males: a report on 4 cases ascertained through a population study. Fertility and Sterility, 24, 390–395.Google Scholar
Stewart, A. L., Keay, A. J., Jacobs, P. A., and Melville, M. M. (1969). A chromosome survey of unselected liveborn children with congenital abnormalities. Journal of Pediatrics, 74, 449–458.Google Scholar
Theilgård, A., Nielsen, J., Sørensen, A., Frøland, A., and Johnsen, S. G. (1971). A psychological-psychiatric study of patients with Klinefelter's syndrome, 47, XXY. Acta Jutlandica, 43: 1. Munksgård: Copenhagen.Google Scholar
Walzer, S., Breau, G., and Gerald, P. S. (1969). A chromosome survey of 2,400 normal newborn infants. Journal of Pediatrics, 74, 438–448.Google Scholar
Widmer, H. A. (1962). Nogle oplysninger om forvaringsklientellet i Horsens. Juristen, 44, 94–104.Google Scholar
Williams, D. (1941). The significance of an abnormal electroencephalogram. Journal of Neurology and Psychiatry, 4, 257–268.Google Scholar
Zeuthen, E., Hansen, M., Christensen, A.-L., and Nielsen, J. (1974). XYY males found in a general male population. Psychiatric-psychological examination. Acta Psychiatrica Scandinavica. (In press.)Google Scholar
Zeuthen, E., and Nielsen, J. (1973). Prevalence of chromosome abnormalities among males examined for military service. Clinical Genetics, 7, 722–728.Google Scholar