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Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa

  • F. Ritschel (a1), J. A. King (a1), D. Geisler (a1), L. Flohr (a1), F. Neidel (a1), I. Boehm (a1), M. Seidel (a1), J. Zwipp (a1), S. Ripke (a2), M. N. Smolka (a2), V. Roessner (a1) and S. Ehrlich (a1) (a3) (a4)...

Abstract

Background.

Patients with anorexia nervosa (AN) are characterized by a very low body weight but readily give up immediate rewards (food) for long-term goals (slim figure), which might indicate an unusual level of self-control. This everyday clinical observation may be quantifiable in the framework of the anticipation-discounting dilemma.

Method.

Using a cross-sectional design, this study compared the capacity to delay reward in 34 patients suffering from acute AN (acAN), 33 weight-recovered AN patients (recAN) and 54 healthy controls. We also used a longitudinal study to reassess 21 acAN patients after short-term weight restoration. A validated intertemporal choice task and a hyperbolic model were used to estimate temporal discounting rates.

Results.

Confirming the validity of the task used, decreased delay discounting was associated with age and low self-reported impulsivity. However, no group differences in key measures of temporal discounting of monetary rewards were found.

Conclusions.

Increased cognitive control, which has been suggested as a key characteristic of AN, does not seem to extend the capacity to wait for delayed monetary rewards. Differences between our study and the only previous study reporting decreased delay discounting in adult AN patients may be explained by the different age range and chronicity of acute patients, but the fact that weight recovery was not associated with changes in discount rates suggests that discounting behavior is not a trait marker in AN. Future studies using paradigms with disorder-specific stimuli may help to clarify the role of delay discounting in AN.

Copyright

Corresponding author

* Address for correspondence: S. Ehrlich, M.D., Department of Child and Adolescent Psychiatry, Translational Developmental Neuroscience Section, Dresden University of Technology, University Hospital Carl Gustav Carus, Fetscherstraße 74, 01307 Dresden, Germany. (Email: transden.lab@gmail.com)

References

Hide All
Ballard, K, Knutson, B (2009). Dissociable neural representations of future reward magnitude and delay during temporal discounting. NeuroImage 45, 143150.
Butler, GKL, Montgomery, AMJ (2005). Subjective self-control and behavioural impulsivity coexist in anorexia nervosa. Eating Behaviors 6, 221227.
Butow, P, Beumont, P, Touyz, S (1993). Cognitive processes in dieting disorders. International Journal of Eating Disorders 14, 319329.
Casper, RC (1990). Personality features of women with good outcome from restricting anorexia nervosa. Psychosomatic Medicine 52, 156170.
Casper, RC, Hedeker, D, McClough, JF (1992). Personality dimensions in eating disorders and their relevance for subtyping. Journal of the American Academy of Child and Adolescent Psychiatry 31, 830840.
Claes, L, Vandereycken, W, Vertommen, H (2005). Impulsivity-related traits in eating disorder patients. Personality and Individual Differences 39, 739749.
Cloninger, CR (1994). Temperament and personality. Current Opinion in Neurobiology 4, 266273.
Coller, M, Williams, MB (1999). Eliciting individual discount rates. Experimental Economics 2, 107127.
Crean, JP, de Wit, H, Richards, JB (2000). Reward discounting as a measure of impulsive behavior in a psychiatric outpatient population. Experimental and Clinical Psychopharmacology 8, 155162.
Critchfield, TS, Kollins, SH (2001). Temporal discounting: basic research and the analysis of socially important behavior. Journal of Applied Behavior Analysis 34, 101122.
Demurie, E, Roeyers, H, Baeyens, D, Sonuga-Barke, E (2012). Temporal discounting of monetary rewards in children and adolescents with ADHD and autism spectrum disorders. Developmental Science 15, 791800.
Evenden, J (1999). Impulsivity: a discussion of clinical and experimental findings. Journal of Psychopharmacology 13, 180192.
Fichter, MM, Quadflieg, N (1999). Strukturiertes Inventar für Anorektische und Bulimische Essstörungen (SIAB). Fragebogen (SIAB-S) und Interview (SIAB-EX) nach DSM-IV und ICD-10. Hogrefe: Göttingen.
Goth, K, Schmeck, K (2009). Das Junior Temperament und Charakter Inventar (JTCI) . Hogrefe: Göttingen.
Green, L, Myerson, J (2004). A discounting framework for choice with delayed and probabilistic rewards. Psychological Bulletin 130, 769792.
Green, L, Myerson, J, Ostaszewski, P (1999). Discounting of delayed rewards across the life span: age differences in individual discounting functions. Behavioural Processes 46, 8996.
Harris, PA, Taylor, R, Thielke, R, Payne, J, Gonzalez, N, Conde, JG (2009). Research electronic data capture (REDCap) – a metadata-driven methodology and workflow process for providing translational research informatics support. Journal of Biomedical Informatics 42, 377381.
Hautzinger, M, Keller, F, Kühner, C (2009). BDI-II. Beck-Depressions-Inventar. Pearson Assessment: Frankfurt.
Heerey, EA, Robinson, BM, McMahon, RP, Gold, JM (2007). Delay discounting in schizophrenia. Cognitive Neuropsychiatry 12, 213221.
Hemmelmann, C, Brose, S, Vens, M, Hebebrand, J, Ziegler, A (2010). Percentiles of body mass index of 18-80-year-old German adults based on data from the Second National Nutrition Survey [in German]. Deutsche Medizinische Wochenschrift 135, 848852.
Holt, DD, Green, L, Myerson, J (2003). Is discounting impulsive? Evidence from temporal and probability discounting in gambling and non-gambling college students. Behavioural Processes 64, 355367.
IBM Corp. (2012). IBM SPSS Statistics for Windows, Version 21.0. IBM Corp.: Armonk, NY.
Jarmolowicz, DP, Cherry, JBC, Reed, DD, Bruce, JM, Crespi, JM, Lusk, JL, Bruce, AS (2014). Robust relation between temporal discounting rates and body mass. Appetite 78, 6367.
Johnson, MW, Bickel, WK (2002). Within-subject comparison of real and hypothetical money rewards in delay discounting. Journal of the Experimental Analysis of Behavior 77, 129146.
Juckel, G, Friedel, E, Koslowski, M, Witthaus, H, Özgürdal, S, Gudlowski, Y, Knutson, B, Wrase, J, Brüne, M, Heinz, A, Schlagenhauf, F (2012). Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia. Neuropsychobiology 66, 5056.
Kirby, KN (2009). One-year temporal stability of delay-discount rates. Psychonomic Bulletin and Review 16, 457462.
Kirby, KN, Maraković, NN (1995). Modeling myopic decisions: evidence for hyperbolic delay-discounting within subjects and amounts. Organizational Behavior and Human Decision Processes 64, 2230.
Kirby, KN, Petry, NM, Bickel, WK (1999). Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls. Journal of Experimental Psychology: General 128, 7887.
Kobiella, A, Ripke, S, Kroemer, NB, Vollmert, C, Vollstädt-Klein, S, Ulshöfer, DE, Smolka, MN (2014). Acute and chronic nicotine effects on behaviour and brain activation during intertemporal decision making. Addiction Biology 19, 918930.
Kromeyer-Hauschild, K, Wabitsch, M, Kunze, D, Geller, F, Geiß, HC, Hesse, V, von Hippel, A, Jaeger, U, Johnsen, D, Korte, W, Menner, K, Müller, G, Müller, JM, Niemann-Pilatus, A, Remer, T, Schaefer, F, Wittchen, H-U, Zabransky, S, Zellner, K, Ziegler, A, Hebebrand, J (2001). Percentiles of body mass index in children and adolescents evaluated from different regional German studies [in German]. Monatsschrift Kinderheilkunde 149, 807818.
Kullmann, S, Giel, KE, Hu, X, Bischoff, SC, Teufel, M, Thiel, A, Zipfel, S, Preissl, H (2014). Impaired inhibitory control in anorexia nervosa elicited by physical activity stimuli. Social Cognitive and Affective Neuroscience 9, 917923.
Lawrence, KA, Allen, JS, Chanen, AM (2010). Impulsivity in borderline personality disorder: reward-based decision-making and its relationship to emotional distress. Journal of Personality Disorders 24, 786799.
Lawyer, SR, Schoepflin, F, Green, R, Jenks, C (2011). Discounting of hypothetical and potentially real outcomes in nicotine-dependent and nondependent samples. Experimental and Clinical Psychopharmacology 19, 263274.
Ledgerwood, DM, Alessi, SM, Phoenix, N, Petry, NM (2009). Behavioral assessment of impulsivity in pathological gamblers with and without substance use disorder histories versus healthy controls. Drug and Alcohol Dependence 105, 8996.
Lilienthal, KR, Weatherly, JN (2013). Decision-making impulsivity in disordered eating: outcomes from a discounting task. Advances in Eating Disorders 1, 148160.
Loewenstein, GF (1988). Frames of mind in intertemporal choice. Management Science 34, 200214.
Logue, AW (1988). Research on self-control: an integrating framework. Behavioral and Brain Sciences 11, 665679.
Madden, GJ, Raiff, BR, Lagorio, CH, Begotka, AM, Mueller, AM, Hehli, DJ, Wegener, AA (2004). Delay discounting of potentially real and hypothetical rewards: II. Between- and within-subject comparisons. Experimental and Clinical Psychopharmacology 12, 251261.
Mazur, JE (1987). An adjusting procedure for studying delayed reinforcement. In The Effect of Delay and of Intervening Events on Reinforcement Value: Quantitative Analyses of Behavior, Volume V (ed. Commons, M. L., Mazur, J. E., Nevin, J. A. and Rachlin, H.), pp. 5573. Erlbaum: Hillsdale, NJ.
Neurobehavioral Systems (2012). Presentation, Version 16.1. Neurobehavioral Systems Inc.: Albany, CA.
Patrick, K, Norman, GJ, Calfas, KJ, Sallis, JF, Zabinski, MF, Rupp, J, Cella, J (2004). Diet, physical activity, and sedentary behaviors as risk factors for overweight in adolescence. Archives of Pediatrics and Adolescent Medicine 158, 385390.
Paul, T, Thiel, A (2005). Eating Disorder Inventory-2 (EDI-2): German Version. Hogrefe: Göttingen.
Petermann, F, Daseking, M (2009). Fallbuch HAWIK-IV. Hogrefe: Göttingen.
Pinto, A, Steinglass, JE, Greene, AL, Weber, EU, Simpson, HB (2014). Capacity to delay reward differentiates obsessive-compulsive disorder and obsessive-compulsive personality disorder. Biological Psychiatry 75, 653659.
Pulcu, E, Trotter, PD, Thomas, EJ, McFarquhar, M, Juhasz, G, Sahakian, BJ, Deakin, JF, Zahn, R, Anderson, IM, Elliott, R (2013). Temporal discounting in major depressive disorder. Psychological Medicine. Published online: 1 November 2013. doi:10.1017/S0033291713002584.
R Core Team (2012). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing: Vienna, Austria.
Reynolds, B (2006). A review of delay-discounting research with humans: relations to drug use and gambling. Behavioural Pharmacology 17, 651667.
Ripke, S, Hübner, T, Mennigen, E, Müller, KU, Rodehacke, S, Schmidt, D, Jacob, MJ, Smolka, MN (2012). Reward processing and intertemporal decision making in adults and adolescents: the role of impulsivity and decision consistency. Brain Research 1478, 3647.
Robbins T, W, Cardinal R, N, DiCiano, P, Halligan, PW, Hellemans, KGC, Lee, JLC, Everitt, BJ (2005). Neuroscience and Drugs of Addiction V.1.0. Foresight: Brain Science, Addiction and Drugs Project (http://egret.psychol.cam.ac.uk/publications/2005/27_Robbins_2005_Foresight_19567_Neuroscience.pdf). Accessed 28 August 2014.
Rounds, JS, Beck, JG, Grant, DM (2007). Is the delay discounting paradigm useful in understanding social anxiety? Behaviour Research and Therapy 45, 729735.
Saelens, B, Epstein, LH (1996). Reinforcing value of food in obese and non-obese women. Appetite 27, 4150.
Scheres, A, de Water, E, Mies, GW (2013). The neural correlates of temporal reward discounting. Wiley Interdisciplinary Reviews: Cognitive Science 4, 523545.
Scherr, J, Ferraro, FR, Weatherly, JN (2010). Associations between impulsivity and body dissatisfaction in females at risk for developing eating disorders. Current Psychology 29, 297306.
Schweighofer, N, Bertin, M, Shishida, K, Okamoto, Y, Tanaka, SC, Yamawaki, S, Doya, K (2008). Low-serotonin levels increase delayed reward discounting in humans. Journal of Neuroscience 28, 45284532.
Shamosh, NA, DeYoung, CG, Green, AE, Reis, DL, Johnson, MR, Conway, ARA, Engle, RW, Braver, TS, Gray, JR (2008). Individual differences in delay discounting relation to intelligence, working memory, and anterior prefrontal cortex. Psychological Science 19, 904911.
Simpson, CA, Vuchinich, RE (2000). Reliability of a measure of temporal discounting. Psychological Record 50, 316.
Steinberg, L, Graham, S, O'Brien, L, Woolard, J, Cauffman, E, Banich, M (2009). Age differences in future orientation and delay discounting. Child Development 80, 2844.
Steinglass, JE, Figner, B, Berkowitz, S, Simpson, HB, Weber, EU, Walsh, BT (2012). Increased capacity to delay reward in anorexia nervosa. Journal of the International Neuropsychological Society: JINS 18, 773780.
Swanson, SA, Crow, SJ, Le Grange, D, Swendsen, J, Merikangas, KR (2011). Prevalence and correlates of eating disorders in adolescents. Results from the National Comorbidity Survey Replication Adolescent Supplement. Archives of General Psychiatry 68, 714723.
Takahashi, T, Oono, H, Inoue, T, Boku, S, Kako, Y, Kitaichi, Y, Kusumi, I, Masui, T, Nakagawa, S, Suzuki, K, Tanaka, T, Koyama, T, Radford, MHB (2008). Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects – an analysis based on Tsallis’ statistics. Neuro Endocrinology Letters 29, 351358.
Von Aster, M, Neubauer, AC, Horn, R (2006). WIE. Wechsler Intelligenztest für Erwachsene. Deutschsprachige Bearbeitung und Adaptation des WAIS-III von David Wechsler. Harcourt Test Services: Frankfurt/Main.
Wagner, A, Aizenstein, H, Venkatraman, VK, Fudge, J, May, JC, Mazurkewicz, L, Frank, GK, Bailer, UF, Fischer, L, Nguyen, V, Carter, C, Putnam, K, Kaye, WH (2007). Altered reward processing in women recovered from anorexia nervosa. American Journal of Psychiatry 164, 18421849.
Watson, KK, Werling, DM, Zucker, NL, Platt, ML (2010). Altered social reward and attention in anorexia nervosa. Frontiers in Psychology 1, 36.
Weber, EU, Johnson, EJ, Milch, KF, Chang, H, Brodscholl, JC, Goldstein, DG (2007). Asymmetric discounting in intertemporal choice: a query-theory account. Psychological Science 18, 516523.
Weller, RE, Avsar, KB, Cox, JE, Reid, MA, White, DM, Lahti, AC (2014). Delay discounting and task performance consistency in patients with schizophrenia. Psychiatry Research 215, 286293.
Weller, RE, Cook, EW 3rd, Avsar, KB, Cox, JE (2008). Obese women show greater delay discounting than healthy-weight women. Appetite 51, 563569.
Wolff, G, Serpell, J (1998). A cognitive model and treatment strategies for anorexia nervosa. In Neurobiology in the Treatment of Eating Disorders (ed. Hoek, H., Treasure, J. and Katzman, M.), pp. 400421. John Wiley & Sons: Chichester.
Zastrow, A, Kaiser, S, Stippich, C, Walther, S, Herzog, W, Tchanturia, K, Belger, A, Weisbrod, M, Treasure, J, Friederich, H-C (2009). Neural correlates of impaired cognitive-behavioral flexibility in anorexia nervosa. American Journal of Psychiatry 166, 608616.
Zhang, L, Rashad, I (2008). Obesity and time preference: the health consequences of discounting the future. Journal of Biosocial Science 40, 97113.

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Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa

  • F. Ritschel (a1), J. A. King (a1), D. Geisler (a1), L. Flohr (a1), F. Neidel (a1), I. Boehm (a1), M. Seidel (a1), J. Zwipp (a1), S. Ripke (a2), M. N. Smolka (a2), V. Roessner (a1) and S. Ehrlich (a1) (a3) (a4)...

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