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Socio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study

  • Jutta Joormann (a1), Samuel A. McLean (a2) (a3), Francesca L. Beaudoin (a4) (a5) (a6) (a7), Xinming An (a2), Jennifer S. Stevens (a8), Donglin Zeng (a9), Thomas C. Neylan (a10) (a11), Gari Clifford (a12), Sarah D. Linnstaedt (a2), Laura T. Germine (a13) (a14) (a15), Scott L. Rauch (a16), Paul I. Musey (a17), Phyllis L. Hendry (a18), Sophia Sheikh (a18), Christopher W. Jones (a19), Brittany E. Punches (a20) (a21), Gregory Fermann (a20), Lauren A. Hudak (a22), Kamran Mohiuddin (a23), Vishnu Murty (a24), Meghan E. McGrath (a25), John P. Haran (a26), Jose Pascual (a27), Mark Seamon (a28), David A. Peak (a29), Claire Pearson (a30), Robert M. Domeier (a31), Paulina Sergot (a32), Roland Merchant (a33), Leon D. Sanchez (a34) (a35), Niels K. Rathlev (a36), William F. Peacock (a37), Steven E. Bruce (a38), Deanna Barch (a39), Diego A. Pizzagalli (a14), Beatriz Luna (a40), Steven E. Harte (a41), Irving Hwang (a42), Sue Lee (a42), Nancy Sampson (a42), Karestan C. Koenen (a43), Kerry J. Ressler (a14) (a44) and Ronald C. Kessler (a42) (a44)...

Abstract

Background

This is the first report on the association between trauma exposure and depression from the Advancing Understanding of RecOvery afteR traumA(AURORA) multisite longitudinal study of adverse post-traumatic neuropsychiatric sequelae (APNS) among participants seeking emergency department (ED) treatment in the aftermath of a traumatic life experience.

Methods

We focus on participants presenting at EDs after a motor vehicle collision (MVC), which characterizes most AURORA participants, and examine associations of participant socio-demographics and MVC characteristics with 8-week depression as mediated through peritraumatic symptoms and 2-week depression.

Results

Eight-week depression prevalence was relatively high (27.8%) and associated with several MVC characteristics (being passenger v. driver; injuries to other people). Peritraumatic distress was associated with 2-week but not 8-week depression. Most of these associations held when controlling for peritraumatic symptoms and, to a lesser degree, depressive symptoms at 2-weeks post-trauma.

Conclusions

These observations, coupled with substantial variation in the relative strength of the mediating pathways across predictors, raises the possibility of diverse and potentially complex underlying biological and psychological processes that remain to be elucidated in more in-depth analyses of the rich and evolving AURORA database to find new targets for intervention and new tools for risk-based stratification following trauma exposure.

Copyright

Corresponding author

Author for correspondence: Jutta Joormann, E-mail: jutta.joormann@yale.edu

References

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Socio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study

  • Jutta Joormann (a1), Samuel A. McLean (a2) (a3), Francesca L. Beaudoin (a4) (a5) (a6) (a7), Xinming An (a2), Jennifer S. Stevens (a8), Donglin Zeng (a9), Thomas C. Neylan (a10) (a11), Gari Clifford (a12), Sarah D. Linnstaedt (a2), Laura T. Germine (a13) (a14) (a15), Scott L. Rauch (a16), Paul I. Musey (a17), Phyllis L. Hendry (a18), Sophia Sheikh (a18), Christopher W. Jones (a19), Brittany E. Punches (a20) (a21), Gregory Fermann (a20), Lauren A. Hudak (a22), Kamran Mohiuddin (a23), Vishnu Murty (a24), Meghan E. McGrath (a25), John P. Haran (a26), Jose Pascual (a27), Mark Seamon (a28), David A. Peak (a29), Claire Pearson (a30), Robert M. Domeier (a31), Paulina Sergot (a32), Roland Merchant (a33), Leon D. Sanchez (a34) (a35), Niels K. Rathlev (a36), William F. Peacock (a37), Steven E. Bruce (a38), Deanna Barch (a39), Diego A. Pizzagalli (a14), Beatriz Luna (a40), Steven E. Harte (a41), Irving Hwang (a42), Sue Lee (a42), Nancy Sampson (a42), Karestan C. Koenen (a43), Kerry J. Ressler (a14) (a44) and Ronald C. Kessler (a42) (a44)...

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