Hostname: page-component-68945f75b7-wph62 Total loading time: 0 Render date: 2024-08-06T01:14:22.122Z Has data issue: false hasContentIssue false
  • English
  • Français

Serum creatine phosphokinase levels and assaultive behaviour of psychotic patients

Published online by Cambridge University Press:  09 July 2009

John S. Isaacs  and
Jerome A. Yesavage
John S. Isaacs
Affiliation:
Veterans Administration Medical Center, Palo Alto, California, and the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
Jerome A. Yesavage*
Affiliation:
Veterans Administration Medical Center, Palo Alto, California, and the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
*
1Address for correspondence: Dr Jerome A. Yesavage Psychiatric Intensive Care Unit, Veterans Administration Medical Center, Palo Alto, CA 94304, USA.
Get access Rights & Permissions [Opens in a new window]

Synopsis

Serum creatine phosphokinase (CPK) levels were compared with assaultive behaviour by 46 psychiatric patients. Significant relationships were found between CPK level and violent behaviour prior to admission and CPK level and seclusion as a danger to others while in hospital. No relationship was found between CPK level and assaultiveness while in hospital.

Type
Preliminary Communication
Information
Psychological Medicine , Volume 14 , Issue 1 , February 1984 , pp. 229 - 231
Copyright
Copyright © Cambridge University Press 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1980). Diagnostic and Statistical Manual of Mental Disorders (third edition) (DSM-III). APA: Washington, D.C.Google Scholar
Bartko, J. J. & Carpenter, W. T. (1976). On the methods and theory of reliability. Journal of Nervous and Mental Disease 163, 307–317.CrossRefGoogle ScholarPubMed
Bengzon, A., Hippius, H. & Kanig, K. (1966). Some changes in the serum during treatment with psychotropic drugs. Journal of Mental and Nervous Disease 143, 369–376.CrossRefGoogle ScholarPubMed
Coffey, J. W., Heath, R. G. & Guschwan, A. F. (1970). Serum creatine kinase, aldolase and copper in acute chronic schizophrenics. Biological Psychiatry 2, 331–339.Google ScholarPubMed
Cunningham, L. A., Rich, C. L., Woodruff, R. A. & Olney, J. W. (1974). Creatine phosphokinase and psychiatric illness. British Journal of Psychiatry 124, 87–91.CrossRefGoogle ScholarPubMed
Ebashi, S., Toyokura, Y., Momoi, H. & Sugita, H. (1959). Creatine phosphokinase activity of sera of progressive muscular dystrophy patients. Journal of Biochemistry 46, 103.Google Scholar
Gosling, K., Kerry, R. J., Orme, J. E. & Owen, G. (1972). Creatine phosphokinase activity in newly admitted psychotic patients. British Journal of Psychiatry 121, 351–355.CrossRefGoogle Scholar
Harding, T. (1974). Serum creatine kinase in acute psychosis. British Journal of Psychiatry 125, 280–285.CrossRefGoogle ScholarPubMed
Hetnarska, L., Prot, J. & Sawicka, E. (1968). Creatine phosphokinase activity in spinal muscular atrophy. Journal of Neurological Science 6, 261–267.CrossRefGoogle ScholarPubMed
Lion, J. R., Kenefich, D. P. & Albert, J. (1974). Clinical Aspects of the Violent Individual. American Psychiatric Association, Task Force Report No. 8.Google Scholar
Lion, J. R., Snyder, W. & Merrill, G. I. (1981). Underreporting of assaults on staff in a state hospital. Hospital and Community Psychiatry 32, 497–498.Google ScholarPubMed
Meltzer, H. Y. (1968). Creatine kinase and aldolase in serum; abnormality common to acute psychosis. Science 159, 1368–1370.CrossRefGoogle Scholar
Meltzer, H. Y. (1970). Increased activity of creatine phosphokinase and aldolase activity in the acute psychoses: case reports. Journal of Psychiatric Research 7, 249–262.CrossRefGoogle ScholarPubMed
Meltzer, H. Y. (1975) Neuromuscular abnormalities in the major mental illnesses. I. Serum enzyme studies. In Biology of the Major Psychoses (ed. Freedman, D. X.), pp. 165–188. Raven Press: New York.Google Scholar
Meltzer, H. Y., Elkum, L. & Moline, R. (1969). Serum enzyme changes in newly admitted psychiatric patients. Archives of General Psychiatry 21, 731–738.CrossRefGoogle ScholarPubMed
Monahan, J. (1981). The Clinical Prediction of Violent Behavior. US Department of Health and Human Services, Crime and Delinquency Series, No. (ADM) 81–921.Google Scholar
Rosalki, S. B. (1967). An improved procedure for serum creatine phosphokinase determination. Journal of Laboratory and Clinical Medicine 69, 696–705.Google ScholarPubMed
Schiavone, D. J. & Kaldor, J. (1965). Creatine phosphokinase levels and cerebral disease. Medical Journal of Australia ii, 790–792.CrossRefGoogle Scholar
Soloff, P. H. & Turner, S. M. (1981). Patterns of seclusion: a prospective study. Journal of Nervous and Mental Disease 169, 37–44.CrossRefGoogle ScholarPubMed
Student, D. & Lion, J. R. (1978). Methodological Issues in Psychopharmacological Research in Violent Individuals. International Society for Research on Aggression, National Institutes of Medicine, Washington, D.C.Google Scholar
Yesavage, J. A., Werner, P. W., Becker, J. M. T., Holman, C. & Mills, M. J. (1981). Inpatient evaluation of aggression in psychiatric patients. Journal of Nervous and Mental Disease 169, 299–302.CrossRefGoogle ScholarPubMed
Yesavage, J. A., Werner, P. W., Becker, J. M. T. & Mills, M. J. (1982). Short-term civil commitment and the violent patient. American Journal of Psychiatry 139, 1145–1149.Google ScholarPubMed