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Evaluation of speech misattribution bias in schizophrenia

Published online by Cambridge University Press:  01 September 2009

M. Stephane ,
M. Kuskowski ,
K. McClannahan ,
C. Surerus  and
K. Nelson
M. Stephane*
Affiliation:
Psychiatry Service line, VA Medical Center, Minneapolis, MN, USA The Domenici Research Center for Mental Illness, VA Medical Center, Minneapolis, MN, USA Brain Sciences Center, VA Medical Center, Minneapolis, MN, USA Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
M. Kuskowski
Affiliation:
Psychiatry Service line, VA Medical Center, Minneapolis, MN, USA Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
K. McClannahan
Affiliation:
Psychiatry Service line, VA Medical Center, Minneapolis, MN, USA The Domenici Research Center for Mental Illness, VA Medical Center, Minneapolis, MN, USA
C. Surerus
Affiliation:
Psychiatry Service line, VA Medical Center, Minneapolis, MN, USA
K. Nelson
Affiliation:
Psychiatry Service line, VA Medical Center, Minneapolis, MN, USA
*
*Address for correspondence: M. Stephane, M.D., VA Medical Center, One Veterans Drive, 116A, Minneapolis, MN55417, USA. (Email: mstephan@umn.edu)
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Abstract

Background

The attribution of self-generated speech to others could explain the experience of verbal hallucinations. To test this hypothesis, we developed a task to simultaneously evaluate (A) operations of self-other distinction and (B) operations that have the same cognitive demands as in A apart from self-other distinction. By adjusting A to B, operations of self-other distinction were specifically evaluated.

Method

Thirty-nine schizophrenia patients and 26 matched healthy controls were required to distinguish between self-generated, other-generated and non-generated (self or other) sentences. The sentences were in the first, second or third person and were read in a male or female voice in equal proportions. Mixed multi-level logistic regression models were used to investigate the effect of group, sentence source, pronoun and gender of the heard sentences on response accuracy.

Results

Patients differed from controls in the recognition of self-generated and other-generated sentences but not in general recognition ability. Pronoun was a significant predictor of response accuracy but without any significant interaction with group. Differences in the gender of heard sentences were not significant. Misattribution bias differentiated groups only in the self-other direction.

Conclusions

These data support the theory that misattribution of self-generated speech to others could result in verbal hallucinations. The syntactic (pronoun) factor could impact self-other distinction in subtypes of verbal hallucinations that are phenomenologically defined whereas the acoustic factor (gender of heard speech) is unlikely to affect self-other distinction.

Keywords

Auditory verbal hallucinationsschizophreniaselfself-other distinctionsource memory
Type
Original Articles
Information
Psychological Medicine , Volume 40 , Issue 5 , May 2010 , pp. 741 - 748
Copyright
Copyright © Cambridge University Press 2009

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References

Allen, P, Amaro, E, Fu, CH, Williams, SC, Brammer, MJ, Johns, LC, McGuire, PK (2007). Neural correlates of the misattribution of speech in schizophrenia. British Journal of Psychiatry 190, 162–169.CrossRefGoogle ScholarPubMed
Allen, PP, Johns, LC, Fu, CH, Broome, MR, Vythelingum, GN, McGuire, PK (2004). Misattribution of external speech in patients with hallucinations and delusions. Schizophrenia Research 69, 277–287.CrossRefGoogle ScholarPubMed
Andreasen, NC (1983). Scale for the Assessment of Negative Symptoms (SANS). University of Iowa Press: Iowa City.Google Scholar
Andreasen, NC (1984). Scale for the Assessment of Positive Symptoms (SAPS). University of Iowa Press: Iowa City.Google Scholar
Blair, JR, Spreen, O (1989). Predicting premorbid IQ: a revision of the National Adult Reading Test. The Clinical Neuropsychologist 3, 129–136.CrossRefGoogle Scholar
Cahill, C, Silbersweig, D, Frith, C (1996). Psychotic experiences induced in deluded patients using distorted auditory feedback. Cognitive Neuropsychiatry 1, 201–211.CrossRefGoogle ScholarPubMed
Caplan, D (1992). Language Structure, Processing and Disorders. MIT Press: Cambridge, MA.Google Scholar
Costafreda, SG, Brébion, G, Allen, P, McGuire, PK, Fu, CH (2008). Affective modulation of external misattribution bias in source monitoring in schizophrenia. Psychological Medicine 1, 1–4.Google Scholar
David, AS (2004). The cognitive neuropsychology of auditory verbal hallucinations: an overview. Cognitive Neuropsychiatry 9, 107–124.Google Scholar
First, MB, Spitzer, RL, Gibbon, M, Williams, JBW (1995). Structured Clinical Interview for Axis I DSM-IV Disorders – Patient Edition (SCID-I/P), Version 2.0. Biometrics Research Department, New York State Psychiatric Institute: New York.Google Scholar
Ford, JM, Mathalon, DH, Heinks, T, Kalba, S, Faustman, WO, Roth, WT (2001). Neurophysiological evidence of corollary discharge dysfunction in schizophrenia. American Journal of Psychiatry 158, 2069–2071.CrossRefGoogle ScholarPubMed
Frith, CD, Done, DJ (1988). Toward a neuropsychology of schizophrenia. British Journal of Psychiatry 153, 437–443.CrossRefGoogle Scholar
Frith, CD, Done, DJ (1989). Experiences of alien control of schizophrenia reflect a disorder of central monitoring of action. Psychological Medicine 19, 359–364.CrossRefGoogle ScholarPubMed
Johns, LC, Gregg, L, Allen, P, McGuire, PK (2006). Impaired verbal self-monitoring in psychosis: effects of state, trait and diagnosis. Psychological Medicine 36, 465–474.CrossRefGoogle ScholarPubMed
Johns, LC, Rossell, S, Frith, C, Ahmad, F, Hemsley, D, Kuipers, E, McGuire, PK (2001). Verbal self-monitoring and auditory verbal hallucinations in patients with schizophrenia. Psychological Medicine 31, 705–715.CrossRefGoogle ScholarPubMed
Levelt, WJM (1989). Speaking from Intention to Articulation. MIT Press: Cambridge, MA.Google Scholar
Linn, EL (1977). Verbal auditory hallucinations: mind, self, and society. Journal of Nervous and Mental Disease 164, 8–17.CrossRefGoogle ScholarPubMed
Mechelli, A, Allen, P, Amaro, E Jr., Fu, CH, Williams, SC, Brammer, MJ, Johns, LC, McGuire, PK (2007). Misattribution of speech and impaired connectivity in patients with auditory verbal hallucinations. Human Brain Mapping 28, 1213–1222.CrossRefGoogle ScholarPubMed
Overall, JE, Gorham, DR (1962). The Brief Psychiatric Rating Scale (BPRS). Psychological Reports 10, 799–812.CrossRefGoogle Scholar
Singer, JD, Willett, JB (2003). Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence. Oxford University Press: New York.CrossRefGoogle Scholar
Sokhi, DS, Hunter, MD, Wilkinson, ID, Woodruff, PW (2005). Male and female voices activate distinct regions in the male brain. Neuroimage 27, 572–578.CrossRefGoogle ScholarPubMed
Sprong, M, Schothorst, P, Vos, E, Hox, J, van Engeland, H (2007). Theory of mind in schizophrenia: meta-analysis. British Journal of Psychiatry 191, 5–13.CrossRefGoogle ScholarPubMed
Stephane, M, Barton, SN, Boutros, NN (2001). Auditory verbal hallucinations and dysfunction of the neural substrates of speech. Schizophrenia Research 50, 63–80.CrossRefGoogle ScholarPubMed
Stephane, M, Hagen, MC, Lee, JT, Uecker, J, Pardo, PJ, Kuskowski, M, Pardo, JV (2006). About the mechanisms of auditory verbal hallucinations: a positron emission tomographic study. Journal of Psychiatry and Neuroscience 31, 396–405.Google ScholarPubMed
Stephane, M, Thuras, P, Nassrallah, H, Georgopoulos, AP (2003). The internal structure of the phenomenology of auditory verbal hallucinations. Schizophrenia Research 61, 185–193.CrossRefGoogle ScholarPubMed
Sumner, P, Husain, M (2008). At the edge of consciousness: automatic motor activation and voluntary control. Neuroscientist 14, 474–486.CrossRefGoogle ScholarPubMed
Tiwari, D, Amar, K (2008). A case of corticobasal degeneration presenting with alien limb syndrome. Age and Ageing 37, 600–601.CrossRefGoogle ScholarPubMed
Versmissen, D, Janssen, I, Johns, L, McGuire, P, Drukker, M, Campo, J, Myin-Germeys, I, Van Os, J, Krabbendam, L (2007). Verbal self-monitoring in psychosis: a non-replication. Psychological Medicine 37, 569–576.CrossRefGoogle ScholarPubMed
Woods, SW (2003). Chlorpromazine equivalent doses for the newer atypical antipsychotics. Journal of Clinical Psychiatry 64, 663–667.CrossRefGoogle ScholarPubMed
Woodward, TS, Menon, M, Whitman, JC (2007). Source monitoring biases and auditory hallucinations. Cognitive Neuropsychiatry 12, 477–494.CrossRefGoogle ScholarPubMed