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Plasma immunoreactive beta-endorphin in bulimics

Published online by Cambridge University Press:  09 July 2009

Donald T. Fullerton*
Affiliation:
Departments of Psychiatry and Pathology and Laboratory Medicine, University of Wisconsin Medical School, Madison, Wisconsin, USA
William J. Swift
Affiliation:
Departments of Psychiatry and Pathology and Laboratory Medicine, University of Wisconsin Medical School, Madison, Wisconsin, USA
Carl J. Getto
Affiliation:
Departments of Psychiatry and Pathology and Laboratory Medicine, University of Wisconsin Medical School, Madison, Wisconsin, USA
Ian H. Carlson
Affiliation:
Departments of Psychiatry and Pathology and Laboratory Medicine, University of Wisconsin Medical School, Madison, Wisconsin, USA
*
1Address for correspondence: Professor D. T. Fullerton, Department of Psychiatry, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA.

Synopsis

The plasma beta-endorphin response to glucose ingestion was compared in 8 bulimics and 8 controls. The bulimics demonstrated a sustained elevation of plasma beta-endorphin unrelated to glucose ingestion throughout the 5-hour study period. It is hypothesized that such an elevation of beta-endorphin is the result of stress and that it may play an important role in the perpetuation of the binge-vomiting cycle.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1986

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