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Milnacipran et trouble obsessionnel-compulsif: étude d'un cas

Published online by Cambridge University Press:  28 April 2020

P Papart  and
M Ansseau
P Papart
Affiliation:
Unité de psychiatrie, centre hospitalier universitaire du Sart-Tilman, B-4000 Liège 1, Belgique
M Ansseau
Affiliation:
Unité de psychiatrie, centre hospitalier universitaire du Sart-Tilman, B-4000 Liège 1, Belgique
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Résumé

Le trouble obsessionnel-compulsif est une affection grave et difficile à traiter. Plusieurs études récentes ont montré une efficacité de certains antidépresseurs, particulièrement sérotoninergiques. Cependant, certains travaux plaident également pour un rôle des voies noradrénergiques. Nous discutons ici l'essai d'un nouvel antidépresseur, le milnacipran, à action noradrénergique et sérotoninergique, chez une patiente atteinte d'un trouble obsessionnel-compulsif rebelle. Le rôle possible de la médication dans la très nette amélioration de la symptomatologie obsessionnelle et dépressive est discuté.

Summary

Summary

Obsessive-compulsive disorder is a severe pathology which is difficult to treat. Several recent studies have shown the efficacy of some antidepressants, particularly of the serotonergic type. Other findings, however, suggest a role for the noradrenergic neurotransmission. We present a trial using a new antidepressant, milnacipran, with both noradrenergic and serotonergic activity, in a patient presenting treatment-resistant obsessive compulsive disorders. The role of the drug in the marked improvement of the patient's symptomatology is discussed.

Keywords

milnaciprantrouble obsessionnel-compulsifmilnacipranobsessive compulsive disorder
Type
Fait clinique
Information
Psychiatry and Psychobiology , Volume 5 , Issue 5 , 1990 , pp. 325 - 327
Copyright
Copyright © European Psychiatric Association 1990

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Footnotes

*

Travail réalisé dans le cadre du programme «Erasmus» European Certificate in Anxiety Disorders (Maastricht, Caen et Oxford, 1989).

References

Références

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