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X.—The Natural History of Yellow Fever in Africa*

Published online by Cambridge University Press:  11 June 2012

A. J. Haddow
A. J. Haddow
Affiliation:
Department of Epidemiology and Preventive Medicine, University of Glasgow, Ruchill Hospital, Glasgow.
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Synopsis

The studies on the epidemiology of yellow fever which have been carried out in Africa in the period 1925–1966 are presented in narrative form.

The original isolation of the virus is described, leading on to the survey work which showed that the infection is widespread in tropical Africa and that monkeys are very important hosts—perhaps the definitive mammalian hosts—of the virus. The discoveries of a monkey-to-man cycle in which the classical vector mosquito, Aedes aegypti, is replaced by A. simpsoni and of a monkey-to-monkey cycle, in which A. africanus is the vector, are described.

Recent epidemics are discussed, particularly that in Ethiopia, where there were about 200,000 cases, with 30,000 deaths, in the period 1960–62 and where the principal vector in the man-to-man cycle was A. simpsoni.

Work on groups of animals other than monkeys is reviewed, with particular reference to studies on the lemuroid Primates of the genus Galago, which are believed to be natural hosts of the virus. It is concluded that there are still many unknown facets in the epidemiology.

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 70 , Issue 3 , 1969 , pp. 191 - 227
Copyright
Copyright © Royal Society of Edinburgh 1969

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Footnotes

*

This paper was assisted in publication by a Grant from the Carnegie Trust for the Universities of Scotland.

References

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