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Sodium butyrate improves small intestine structure regardless of zinc oxide supplementation

Published online by Cambridge University Press:  23 November 2017

H M Miller ,
R D Slade ,
F H Reynolds  and
S M Carroll
H M Miller*
Affiliation:
University of Leeds, Leeds, United Kingdom
R D Slade
Affiliation:
University of Leeds, Leeds, United Kingdom
F H Reynolds
Affiliation:
University of Leeds, Leeds, United Kingdom
S M Carroll
Affiliation:
University of Leeds, Leeds, United Kingdom
*
Email: h.m.miller@leeds.ac.uk
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Extract

Post weaning piglet performance is often associated with a growth check (LeDividich and Seve, 2000) which is a key concern to the pig industry. The ban of in-feed antimicrobial growth promoters (AGPs) has increased this concern. Sodium butyrate (NaB) has been shown to reduce intestinal inflammation and stimulate enterocyte growth in humans (Ogawa et al., 2003) and thus appears to be a possible alternative to AGPs in diets for weaned pigs. Zinc oxide (ZnO) is normally added to weaner diets to control post weaning diarrhoea. The objective of this experiment was to compare varying levels of dietary supplementation of NaB both with and without ZnO to determine whether NaB can improve piglet performance alone or in combination with ZnO.

Type
Theatre presentations
Information
Proceedings of the British Society of Animal Science , Volume 2006 , March 2006 , pp. 28
Copyright
Copyright © The American Society of International Law 2016

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References

Le Dividich, J. and Seve, B. (2000) Effects of underfeeding during the weaning period on growth, metabolism and hormonal adjustments in the piglet. Domestic Animal Endocrinology 19:63-74.CrossRefGoogle ScholarPubMed
Ogawa, H., Rafiee, P., Fisher, P., Johnson, N.A., Otterson, M. F. and Binion, D. G. (2003) Butyrate modulates gene and protein expression in human intestinal endothelial cells. Bioch. & Biophys.Res. Comm., 309, 512-519.Google Scholar