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The relationship between defensin genes polymorphism and milk somatic cell score, milk production, milk composition and reproductive traits in Holstein cows

Published online by Cambridge University Press:  20 November 2017

S. Khorsand Parizad*
Affiliation:
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, P.O. Box: 91775-1163, Mashhad, Iran.
F. Eftekhari Shahroudi
Affiliation:
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, P.O. Box: 91775-1163, Mashhad, Iran.
R. Valizadh
Affiliation:
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, P.O. Box: 91775-1163, Mashhad, Iran.
M.R. Nasiri
Affiliation:
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, P.O. Box: 91775-1163, Mashhad, Iran.
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Extract

Antimicrobial peptides represent an abundant of innate immunity with over 300 different protein sequences described in species ranging from insects to mammals (Boman, 1995). One group of such peptides, due to its antibiotic and cytotoxic activity against bacteria, viruses and fungi was called defensins. Expressions of ß-defensin genes were shown in the cow’s mammary gland and in famale urogenital tract (Ryniewicz etal. 2002). Cattle defensin genes have been localized on chromosome 27. Because defensin peptides protect animals against bacterial, viral and fungal infections, the genes encoding these peptides seem to be potential markers in studies on the genetically determined resistance (or susceptibility) of the mammary gland and also on the reproductive rate. This experiment was conducted to study the presence and comparing the frequencies of various alleles of defensin genes in cows differing in udder health statuses and in some reproductive traits.

Type
Poster Presentations
Copyright
Copyright © The British Society of Animal Science 2004

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References

Boman, H.G., 1995. Peptide antibiotics and their role in innate immunity. Immunol 13: 6192.Google Scholar
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Ryniewicz, Z. L., Zwierzchowski, Bagnicka., E., Krzyzewski, J., and Strzalkowska, N., 2002. Preliminary investigation on the polymorphism of defensin genes in cattle – relation with milk somatic cell count. Animal Science Papers and Reports 20: 125131.Google Scholar