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The acute phase protein response during sub-clinical post weaning colibacillosis in pigs depends on the level of dietary protein

Published online by Cambridge University Press:  23 November 2017

J G M Houdijk ,
F M Campbell ,
P D Fortomaris ,
P D Eckersall  and
I Kyriazakis
J G M Houdijk*
Affiliation:
Animal Nutrition and Health Department, Scottish Agricultural College, Edinburgh, UK
F M Campbell
Affiliation:
Faculty of Veterinary Medicine, University of Glasgow, Glasgow, UK
P D Fortomaris
Affiliation:
Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
P D Eckersall
Affiliation:
Faculty of Veterinary Medicine, University of Glasgow, Glasgow, UK
I Kyriazakis
Affiliation:
Veterinary Faculty, University of Thessaly, Karditsa, Greece
*
Email: jos.houdijk@sac.ac.uk
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Extract

The concentration of most plasma acute phase proteins (APP) increases at times of clinical infection in pigs (Murata et al., 2004) and may be used as a marker to describe objectively pig health status. However, whether sub-clinical gastrointestinal infections also induce APP responses is less well known. Here, we have assessed whether experimentally induced sub-clinical post-weaning colibacillosis (PWC) affects the concentration of the two APP, i.e. haptoglobin (Hp) and C-reactive protein (CRP), which are two major acute phase proteins in pigs (Murata et al., 2004). Current research aims to reduce sub-clinical PWC through the development of pig feeding strategies that do not rely on in-feed anti-microbial growth promoters (AGP). One such strategy explores the possibility of temporarily lowering dietary protein content (Wellock et al., 2006). Therefore, an additional objective was to assess whether the APP response observed was sensitive to the level of dietary protein.

Type
Theatre presentations
Information
Proceedings of the British Society of Animal Science , Volume 2006 , March 2006 , pp. 71
Copyright
Copyright © The American Society of International Law 2016

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References

Murata, H., Shimada, N. and Yoshioka, M. (2004). Current research on acute phase proteins in veterinary diagnosis: an overview. The Veterinary Journal 168: 28-40.Google Scholar
Wellock, I., Fortomaris, P. D., Houdijk, J.G.M. and Kyriazakis, I. (2006). The effect of dietary protein supply on the health and performance of newly weaned pigs experimentally challenged with enterotoxigenic Escherichia coli . Proceedings of the British Society of Animal Science: 114 Google Scholar