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Succinylcholine and halothane as a field test for the heterozygote at the halothane locus in pigs

Published online by Cambridge University Press:  22 November 2017

A.J. Webb
Affiliation:
AFRC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
P. Imlah
Affiliation:
Royal (Dick) School of Veterinary Studies, Roslin, Midlothian EH25 9RG
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Extract

The halothane gene (HALn) has beneficial effects on lean yield, and adverse effects on stress susceptibility, meat quality and litter size. The gene appears additive for lean content, but largely recessive for halothane sensitivity and other traits. Manipulating the frequency of the gene can lead to a worthwhile improvement in performance. At present, complete elimination of the gene requires expensive test matings, and a cheap and accurate method is needed for detecting heterozygotes. Reaction to the muscle relaxant succinylcholine was therefore investigated as a possible method of distinguishing the heterozygote (Nn) from the normal homozygote (NN).

Type
Genetics
Copyright
Copyright © The British Society of Animal Production 1984

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