The Disaster Medicine Centre “Zaschita” is a coordinating center with the general goal of management and medical relief delivery in response to major emergencies. The Russian Disaster Medicine Service has accumulated a national and international experiences of emergency responses to earthquakes (Columbia 1999, Neftegorsk 1995, Turkey 1999, Iran 2003, Afghanistan 2002, China 2008, etc.). The Health Ministries of the Russian Federation and of Peoples Republic of China have concluded a treaty of collaborative activities in the field of in public health services and disaster medicine. The promotion of cooperation in health sector is based on the key elements of collaboration, which is an a method coping with emergencies. All activities have been discussed during annual meetings, and are planned for participants on the basis of practical field experience and of emergency medical care technologies. These include: (1) mechanisms of trans-boundary field collaboration in management during major disasters; (2) sharing of field experiences for coping with natural disasters; (3) early warning networks and information technologies; (4) staff preparedness programs and postgraduate education; (5) new psycho-physiological technologies for staff selection, training, and conformity of medical teams; (6) coordination and management of international-scale exercises; (7) technology of medical relief provided for injured in major disasters; and (8) lessons learned from technological emergencies. The details of the consequences and issues associated with mutual management will be discussed.