Hostname: page-component-848d4c4894-tn8tq Total loading time: 0 Render date: 2024-06-21T13:09:08.828Z Has data issue: false hasContentIssue false

Powder Diffraction Data of Three Tetrahydropyridinyl Oxime Cognition Activators of Formula C8H15N2O+Cl

Published online by Cambridge University Press:  10 January 2013

G. Bandoli
Affiliation:
Department of Pharmaceutical Sciences, Via Marzolo, 5-35131 Padua, Italy
M. Nicolini
Affiliation:
Department of Pharmaceutical Sciences, Via Marzolo, 5-35131 Padua, Italy
A. Ongaro
Affiliation:
Department of Pharmaceutical Sciences, Via Marzolo, 5-35131 Padua, Italy

Abstract

Indexed X-ray powder diffraction data are reported for three tetrahydropyridinyl oxime cognition activators. For these drugs of formula C8H15N2O+Cl powder diffraction data calculated from single crystal structure determinations are also presented and compared to the experimentally observed powder diffraction data. Comparison of experimental and calculated powder patterns assures that single crystals are good representatives of the commercial powdered samples.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Appleman, D.E. & Evans, H.T. Jr (1973). Report PB216188, U.S. Dept. of Commerce, National Technical Information Service, 5825 Port Royal Rd., Springfield, VA 22151, U.S.A.Google Scholar
Bandoli, G., Dolmella, A., Moos, W.H., Nicolini, M., & Ongaro, A. (1991a). J. Cryst. Spec. Res. 21, 419429.CrossRefGoogle Scholar
Bandoli, G., Nicolini, M., & Ongaro, A. (1991b). Pow. Diff. 6, 196199.CrossRefGoogle Scholar
Gamzu, E.R., Hoover, T.M., Gracon, S.I., & Ninteman, M.V. (1989). Drug Devel Res. 18, 177189.CrossRefGoogle Scholar
Hershenson, F.M. & Moos, W.H. (1986). J. Med. Chem. 29, 11251130.CrossRefGoogle Scholar
Lowe-Ma, C.K. (1991). Pow. Diff. 6, 3135.CrossRefGoogle Scholar
Moos, W.H., Davis, R.E., Schwarz, R.D. & Gamzu, E.R. (1988). Med. Res. Rev. 8, 353391.CrossRefGoogle Scholar
Robinson, W. & Sheldrick, G.M. (1988). In Crystallographic Computing 4, Isaacs, N.W. & Taylor, M.R. (eds.), 366377. Oxford University Press.Google Scholar
Smith, G.S. & Snyder, R.J. (1979). J. Appl. Crystallogr. 12, 6065.CrossRefGoogle Scholar