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Sugar Coated Semiconductors: Model Surfaces to Study Biological Adhesion

Published online by Cambridge University Press:  21 February 2011

Mark Mastandrea  and
Mark D. Bednarski
Mark Mastandrea
Affiliation:
The Department of Chemistry, University of California, Berkeley, CA 94720 The Center for Advanced Materials, Lawrence Berkeley Laboratory, Berkeley, CA 94720
Mark D. Bednarski
Affiliation:
The Department of Chemistry, University of California, Berkeley, CA 94720 The Center for Advanced Materials, Lawrence Berkeley Laboratory, Berkeley, CA 94720
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Abstract

Certain molecules when placed in contact with a surface can bind to form well-ordered two dimensional arrays. This process is called molecular selfassembly (MSA), and it is emerging as an important method to control the interactions between a surface and its environment (interfacial properties). Molecular self-assembly uses the fundamental forces between molecules (Van der Waals interactions, hydrophobic effects and hydrogen bonding) to form highly ordered macromolecular systems. This process has been used to synthesize molecular films on a variety of surfaces including glass, gold, alumina, platinum, and silicon. The objective of this paper is to describe the application of molecular self-assembled films to the study of biological systems. Specifically, we will describe methods to synthesize and characterize surfaces that contain molecules that bind to bacteria and viruses. We will also evaluate the use of surface science techniques to characterize the physical and chemical properties of these surfaces, and we will attempt to correlate these properties with the adhesion of biological molecules.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 174: Symposium R – Materials Synthesis Utilizing Biological Processes , 1989 , 277
Copyright
Copyright © Materials Research Society 1990

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