Hostname: page-component-8448b6f56d-tj2md Total loading time: 0 Render date: 2024-04-18T06:49:37.968Z Has data issue: false hasContentIssue false

Smart Hydrogels Designed for use in Microfabricated Sensor Arrays

Published online by Cambridge University Press:  06 June 2013

Jeffrey S. Bates
Affiliation:
Department of Materials Science and Engineering, University of Utah, 122 Central Campus Drive, Room 304, Salt Lake City, UT 84112, U.S.A.
Seung Hei Cho
Affiliation:
Department of Chemical Engineering, University of Utah, 50 Central Campus Drive, Room 3290, Salt Lake City, UT 84112 U.S.A.
Prashant Tathireddy
Affiliation:
Department of Electrical and Computer Engineering, University of Utah, 50 Central Campus Drive, Room 3280, Salt Lake City, UT 84112 U.S.A.
Loren W. Rieth
Affiliation:
Department of Electrical and Computer Engineering, University of Utah, 50 Central Campus Drive, Room 3280, Salt Lake City, UT 84112 U.S.A.
Jules J. Magda
Affiliation:
Department of Chemical Engineering, University of Utah, 50 Central Campus Drive, Room 3290, Salt Lake City, UT 84112 U.S.A.
Get access

Abstract

Hydrogels are considered smart materials because they respond to environmental stimuli. Sensors that monitor the body’s pH levels would be helpful for doctors to determine the severity of a patient’s condition, especially if they exhibit signs of shock. The motivation of this project is to create a biomedical device that can be worn sublingually or implanted into the body to help doctors with diagnosing a patient’s condition. The magnitude of the swelling/deswelling behavior can be measured by placing a sample of the hydrogel in a piezoresistive sensor. The degree of swelling/deswelling is directly proportional to the change in pH of the aqueous solution it is placed in. In this study, a variety of compositions of pH responsive hydrogels were designed and tested to determine the response time and magnitude for use in both macro and micro sensor arrays. This pressure sensor has been designed for use with thinner gels than have been used in the past. The results for swelling time and magnitude were compared to determine the effect of the thickness of the hydrogel samples on the swelling/deswelling kinetics of the material in order to find the appropriate composition, thickness and device that will yield the desired response rate and sensitivity.

Type
Articles
Copyright
Copyright © Materials Research Society 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

De, S. K., Aluru, N. R., Johnson, B., Crone, W. C., Beebe, D. J., Moore, J., Journal of Microelectromechanical Systems 11, 544 (2002).10.1109/JMEMS.2002.803281CrossRefGoogle Scholar
Liu, M., Guo, T., Journal of Applied Polymer Science 82, 1515 (2001).10.1002/app.1990CrossRefGoogle Scholar
Kuckling, D., Hoffman, J., Plotner, M., Ferse, D., Kretschmer, K., Adler, H. P., Arndt, K., Reichelt, R., Polymer 44, 4455 (2003).10.1016/S0032-3861(03)00413-0CrossRefGoogle Scholar
Shin, J., Braun, P. V., Lee, W., Sensors and Actuators B: Chemical 150, 183 (2010).10.1016/j.snb.2010.07.018CrossRefGoogle Scholar
Iwata, T., Suzuki, K., Amaya, N., Higuchi, H., Masunaga, H., Sasaki, S., Kikuchi, H., Macromolecules 42, 2002 (2009).10.1021/ma802464wCrossRefGoogle Scholar
Galeav, I. Y., Mattiason, B., Trends in Biotechnology 17, 335 (1999).10.1016/S0167-7799(99)01345-1CrossRefGoogle Scholar
Kurdikar, D. L., Peppas, N. A., Macromolecules 27, 733 (1994).10.1021/ma00081a017CrossRefGoogle Scholar
Herber, S., Olthius, W., Bergeveld, P., van den Berg, A., Sensors and Actuators B 103, 284 (2004).10.1016/j.snb.2004.04.113CrossRefGoogle Scholar
Herber, S., Bomer, J., Olthius, W., Bergeveld, P., van den Berg, A., Biomedical Microdevices 7, 197 (2005).10.1007/s10544-005-3026-5CrossRefGoogle Scholar
ter Steege, R. W. F., Herber, S., Olthius, W., Bergeveld, P., van den Berg, A., Kolkman, J. J., Journal of Clinical Monitoring and Computing 21, 83 (2007).10.1007/s10877-006-9060-xCrossRefGoogle Scholar
Lin, G., Chang, S., Kuo, C.-H., Magda, J., Solzbacher, F., Sensors and Actuators B: Chemical 136, 186 (2009).10.1016/j.snb.2008.11.001CrossRefGoogle Scholar
Schulz, V., Guenther, M., Gerlach, G., Magda, J. J., Tathireddy, P., Rieth, L., Solzbacher, F., Smart Struct Mater Nondestruct Eval Health Monitor Diagn 7827, 1 (2009).Google Scholar
Gerlach, G., Guenther, M., Sorber, J., Suchanek, G., Sensors and Actuators B 111, 555 (2005).10.1016/j.snb.2005.03.040CrossRefGoogle Scholar