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γ-Ray Irradiation Practical Conditions for Low Molecular Weight Chitosan Material Production

Published online by Cambridge University Press:  01 February 2011

Rangrong Yoksan
Affiliation:
The Petroleum and Petrochemical College, Chulalongkorn University, Phya Thai, Bangkok 10330, THAILAND
Mitsuru Akashi
Affiliation:
Graduate School of Engineering, Osaka University, Yamada, Suita, Osaka 565–0871, JAPAN
Mikiji Miyata
Affiliation:
Graduate School of Engineering, Osaka University, Yamada, Suita, Osaka 565–0871, JAPAN
Siriratana Biramontri
Affiliation:
Office of Atomic Energy for Peace, Ministry of Science and Technology, Bangkok 10900, THAILAND
Suwabun Chirachanchai
Affiliation:
The Petroleum and Petrochemical College, Chulalongkorn University, Phya Thai, Bangkok 10330, THAILAND
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Abstract

The present work focuses on the γ-ray irradiation doses and conditions (dry solid state, solid state dispersing in 0.5–2 % aqueous H2O2 solution, solid state dispersing in 1% aqueous acetic acid, and 2% aqueous K2S2O8) to determine the level that the molecular weight of chitosan is lowered significantly without changing its primary structure. Molecular weight of chitosan (105-106 Dalton) is reduced approximately 50% under the γ-ray dose of 20 kGy in the dry solid state. The decrease in molecular weight is enhanced up to 80% when chitosan is suspended in 0.5–2 % aqueous H2O2 solution during γ-ray irradiation. In either condition, the backbone structure of the irradiated product is maintained with little change in the terminal chain. In the cases of (i) chitosan suspended in 2% aqueous K2S2O8 and (ii) chitosan in 1% aqueous acetic acid, chitosans lose their primary structures and physical properties.

Type
Research Article
Copyright
Copyright © Materials Research Society 2004

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References

REFERENCES

1. Kurita, K., Yoshino, H., Yokota, K., Ando, M., Inoue, S., Ishii, S., and Nishimura, S.I., Macromolecules 25, 37863790 (1992).Google Scholar
2. Lim, L.Y., Khor, E., and Koo, O., J. Biomed. Mater. Res. 43(3), 282290 (1998).Google Scholar
b) Wenwei, Z., Xiaoguang, Z., Li, Y., Yuefang, Z., and Jiaazhen, S. Polym. Deg. Stab. 41, 8384 (1993).Google Scholar
3. Ulanski, P. and Rosiak, J., Radiat. Phys. Chem. 39(1), 5357 (1992).Google Scholar
4. Wang, W., Bo, S., Li, S., and Qin, W., Int. J. Biol. Macromol. 13, 281285 (1991).Google Scholar