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Optical Transduction Schemes for Molecularly Imprinted Polymer Sensors

Published online by Cambridge University Press:  01 February 2011

George M. Murray  and
Glen E. Southard
George M. Murray
Affiliation:
Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723–6099
Glen E. Southard
Affiliation:
Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723–6099
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Abstract

Molecular imprinting is a useful technique for making a chemically selective binding site. [1] The method involves building a synthetic polymeric scaffold of molecular compliments containing the target molecule with subsequent removal of the target to leave a cavity with a structural “memory” of the target. Molecularly imprinted polymers can be employed as selective adsorbents of specific molecules or molecular functional groups. Sensors for specific molecules can be made using optical transduction through chromophores residing in the imprinted site. The use of metal ions as chromophores can improve selectivity due to directional bonding. The combination of molecular imprinting and spectroscopic selectivity can result in sensors that are highly sensitive and nearly immune to interferences. [2]

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 787: Symposium G – Molecularly Imprinted Materials , 2003 , G5.1
Copyright
Copyright © Materials Research Society 2004

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References

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