Skip to main content Accessibility help
×
Home

Comparison of -OH and -NH2 Functional Group Substitution on PTFE Surface with V-UV Photon Irradiation for Protein Adsorption

  • Yuji Sato (a1), Naoki Kobayashi (a1) and Masataka Murahara (a1)

Abstract

Poly-tetrafluoroethylene [PTFE] presents few rejections in a living body but has low tissue affinity. Then, the soft tissue implant material that has not only high biocompatibility but also superb bondability has been developed by photo-chemically substituting the hydrophilic of –OH or –NH2 groups on the PTFE surface with V-UV photon irradiation. The protein adsorption of the sample before and after treatment was also evaluated by scanning electron microscope [SEM] and attenuated total reflection Fourier-transform infrared [ATR FT-IR], using bovine serum albumin [ALB] and fibrin [FIB] solution as a protein index in biocompatibility test. From the results, it has been confirmed that the protein adsorption increased with the increase in the hydrophilic group's substitution density. The -OH incorporated sample adsorbed the ALB and FIB more than the -NH2 incorporated sample; the amount of the ALB and FIB sticking became 2.3 times larger than that of the non-treatment sample.

Copyright

References

Hide All
1. Okada, T. and Ikada, Y., J. Biomater. Sci. Polymer Edn, 7 No.2, 171180 (1999)
2. Martins, M.C.L., Wang, D., Ji, J., Feng, L., Barbosa, M.A., Biomaterials 24, 20672076 (2003)
3. Satriano, C. and Marletta, G., J. Mater. Sci., Mater. in Medicine 14, 663670 (2003)
4. Lee, J. S., Sugioka, K. and Toyoda, K., Appl. Phys. Lett. 65 No.4, 400402 (1994)
5. Sato, Y., Parel, J. M. and Murahara, M., Mater. Res. Soc. Symp. Proc. 752, 8388 (2003)
6. Sato, Y., Tanizawa, K., Manns, F., Parel, J. M. and Murahara, M., Proc. SPIE 4951, 92102 (2003)
7. Omuro, H., Hamada, K., Nakajima, T., Sinpuku, E., Nakagawa, M., Fukuda, H. and Murahara, M., Mater. Res. Soc. Symp. Proc. 711, 8590 (2002)
8. Okoshi, M., Murahara, M. and Toyoda, K., J. Mater. Res. 7, 19121916 (1992)
9. Murahara, M. and Okoshi, M., J. Adhesion Sci. Technol. 9, 15931599 (1995)
10. Murahara, M. and Toyoda, K., J. Adhesion Sci. Technol. 9, 16011609 (1995)
11. Okoshi, M. and Murahara, M., App. Phys. Lett. 72, 26162618 (1998)
12. Sato, Y., Parel, J. M. and Murahara, M., Mater. Res. Soc. Symp. Proc. 711, 277282 (2002)
13. Okabe, H., Photochemistry of Small Molecules, 62–163, a Wiley Interscience, N.Y. (1978)

Comparison of -OH and -NH2 Functional Group Substitution on PTFE Surface with V-UV Photon Irradiation for Protein Adsorption

  • Yuji Sato (a1), Naoki Kobayashi (a1) and Masataka Murahara (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed