Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-19T22:25:55.739Z Has data issue: false hasContentIssue false

Carbon/Nafion® Nanocomposite Thin Films as Potential Matrix-free Laser Desorption-Ionization Mass Spectroscopy Substrates

Published online by Cambridge University Press:  01 February 2011

A. Kaan Kalkan
Affiliation:
Penn State Nanofabrication Facility, The Pennsylvania State University, University Park, PA 16802 NanoHorizons Inc., State College, PA 16803
Stephen J. Fonash
Affiliation:
Penn State Nanofabrication Facility, The Pennsylvania State University, University Park, PA 16802 NanoHorizons Inc., State College, PA 16803
Get access

Abstract

Carbon/Nafion® nanocomposite thin films developed through a low-cost procedure were shown to function as high-sensitivity, low-noise, high-throughput laser desorption-ionization mass spectroscopy substrates for small molecule detection without the need of organic matrices. Our nanocomposite approach combines the strong light absorption feature of amorphous carbon with Nafion®'s efficient protonating capability to yield superior laser desorption-ionization.

Type
Research Article
Copyright
Copyright © Materials Research Society 2004

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Wei, J., Buriak, J. M., and Suizdak, G., Nature 399, p. 243, (1999).Google Scholar
2. Cuiffi, J. D., Hayes, D. J., Fonash, S. J., Brown, K. N., and Jones, A. D., Anal. Chem. 73, 1292, (2001).Google Scholar
3. Shen, Z., Thomas, J. J., Averbuj, C., Broo, K. M., Engelhard, M., Crowell, J. E., Finn, M. G., and Siuzdak, G., Anal. Chem. 73,. 612, (2001).Google Scholar
4. Kruse, R. A., Li, X., Bohn, P. W., and Sweedler, J. V., Anal. Chem. 73, 3639, (2001).Google Scholar