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Synthetic biology with nanomaterials

Published online by Cambridge University Press:  19 March 2018

Sanhita Ray ,
Ahana Mukherjee ,
Pritha Chatterjee ,
Kaushik Chakraborty  and
Anjan Kr Dasgupta Open the ORCID record for Anjan Kr Dasgupta [Opens in a new window]
Sanhita Ray
Affiliation:
Department of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata-700019, West Bengal, India
Ahana Mukherjee
Affiliation:
Department of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata-700019, West Bengal, India
Pritha Chatterjee
Affiliation:
Department of Biochemistry and Molecular Biology, University of California at Riverside, Riverside, CA 92521, USA
Kaushik Chakraborty
Affiliation:
Centre for Research in Nanoscience and Nanotechnology, JD 2, Sector III, Salt Lake, Kolkata-700 098, West Bengal, India
Anjan Kr Dasgupta*
Affiliation:
Department of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata-700019, West Bengal, India
*
Address all correspondence to Anjan Kr Dasgupta at adgcal@gmail.com; adbioc@caluniv.ac.in
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Abstract

Magnetic field has been used to trigger biofilm formation. Iron oxide nanoparticles were attached to bacterial cells and cells were aggregated by application of magnetic field. Artificial cellular crowding triggered quorum sensing and led to the formation of biofilm at the sub-threshold population. Aggregation process was monitored by studying temporal dynamics of capacitance and conductance profiles. Capacitive profile exhibited a plateau upon introduction of magnetic field which was retained even after field was removed. This hysteresis property signified biofilm initiation in response to artificial crowding. This work demonstrates how synthetic biology is enabled by including nanoparticles in the interactome.

Type
Research Letters
Information
MRS Communications , Volume 8 , Issue 1 , March 2018 , pp. 100 - 106
Copyright
Copyright © Materials Research Society 2018 

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